research Repurposing Steroidogenesis Inhibitors for the Therapy of Neuropsychiatric Disorders: Promises and Caveats
Drugs for hormone-related conditions might help treat mental disorders but could have serious side effects.
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research On the Correlation Between the Curvature of the Human Eyelash and Its Geometrical Features
Eyelash curvature is linked to the thickness of the cuticle layer at the root.
research Evidence of the Moderating Role of Hair Cortisol and Hair Cortisone in the Relationship Between Work Stress and Depression Symptoms Among Chinese Fishermen
Hair cortisol and cortisone levels may affect how work stress influences depression in Chinese fishermen.
research Study of Quality of Life in Patients with Premature Graying of Hair in Western Indian Population
Premature graying of hair significantly harms psychological and social wellbeing.
research Definition of Hyperandrogenism
The document suggests new ways to assess and diagnose hyperandrogenism to improve accuracy.
research Seasonality, Climatic Unpredictability, Food Deprivation, and Polycystic Ovary Syndrome
PCOS may have evolved as an advantage in past environments with food scarcity.
research Evaluation of Dry Eye and Meibomian Gland Dysfunction in Female Androgenetic Alopecia Patients
Female hair loss patients more likely to have dry eye and gland issues.
research The Effect of Herbal Extract on Hair Growth in Female Androgenetic Alopecia
Herbal extract improves hair growth in female pattern baldness.
research Criteria for Defining Polycystic Ovary Syndrome as a Predominantly Hyperandrogenic Syndrome: An Androgen Excess Society Guideline
Polycystic Ovary Syndrome should be seen mainly as a condition of excess male hormones, with a focus on this in its definition.
research American Association of Clinical Endocrinologists, American College of Endocrinology, and Androgen Excess and PCOS Society Disease State Clinical Review: Guide to the Best Practices in the Evaluation and Treatment of Polycystic Ovary Syndrome - Part 1
The guide recommends specific methods for diagnosing PCOS and various treatments for its symptoms, while considering the health impacts on adolescents.
research Evidence-Based and Potential Benefits of Metformin in Polycystic Ovary Syndrome: A Comprehensive Review
Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.
research Diagnostic and Predictive Value of Horizontal Sections of Scalp Biopsy Specimens in Male Pattern Androgenetic Alopecia
Horizontal scalp biopsy sections effectively diagnose and predict MPAA, with follicular density and inflammation impacting hair regrowth.
research The Rotterdam Study: 2014 Objectives and Design Update
The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.
research Antiandrogens for the Treatment of Hirsutism: A Systematic Review and Meta-Analyses of Randomized Controlled Trials
Antiandrogens are somewhat effective in reducing excessive hair growth in women.
research Morpho-Regulation of Ectodermal Organs
Modulating BMP activity changes the number, size, shape, and type of ectodermal organs.
research Insulin Sensitizers for the Treatment of Hirsutism: A Systematic Review and Meta-Analyses of Randomized Controlled Trials
Insulin sensitizers may slightly reduce hirsutism but are less effective than other treatments.
research Testosterone, Dihydrotestosterone, and Incident Cardiovascular Disease and Mortality in the Cardiovascular Health Study
DHT may increase the risk of heart disease and death in elderly men.
research Minoxidil: A Review of Its Pharmacological Properties and Therapeutic Use
Minoxidil effectively treats severe hypertension but may cause side effects, so careful monitoring is needed.
research Global Burden of Skin Disease as Reflected in Cochrane Database of Systematic Reviews
The representation of skin conditions in medical reviews partly matches their real-world impact.
research Sulfation of Minoxidil by Liver Sulfotransferase
Liver enzyme helps minoxidil work better for blood vessel relaxation.
research Pharmacological Interventions for Treating Chronic Prostatitis/Chronic Pelvic Pain Syndrome
Some drugs may reduce prostatitis symptoms short-term with few side effects.
research Prostate Cancer Incidence Among Finasteride and Alpha-Blocker Users in the Finnish Prostate Cancer Screening Trial
Finasteride might lower the risk of low-grade prostate cancer but not high-grade cancer, while alpha-blockers might reduce high-grade cancer risk.
research Putative Role for Insulin Resistance in Depression Risk in Polycystic Ovary Syndrome
Insulin resistance is significantly linked to a higher risk of depression in women with PCOS.
research Dutasteride
Dutasteride effectively treats enlarged prostate, reduces prostate cancer risk, and promotes hair regrowth with few side effects.
research Review of Fluconazole Properties and Analytical Methods for Its Determination
Fluconazole is an effective antifungal medication with potential side effects and lacks official analytical methods for its determination.
research Dutasteride Improves Male Pattern Hair Loss in a Randomized Study in Identical Twins
Dutasteride helps slow hair loss and boosts hair growth.
research Surrogate End-Points or Primary Outcomes in Clinical Trials in Women with Polycystic Ovary Syndrome?
The document suggests that clinical trials for PCOS should focus on meaningful primary outcomes like live birth rates, rather than less reliable surrogate markers.
research Systematic Review and Meta-Analysis of the Efficacy and Safety of Leflunomide and Methotrexate in the Treatment of Rheumatoid Arthritis
Leflunomide and methotrexate are equally effective for rheumatoid arthritis but have different side effects.
research Systemic Lupus Erythematosus: Definitions, Contexts, Conflicts, Enigmas
The document concludes that anti-dsDNA antibodies are not unique to SLE and their use as indicators is doubtful, highlighting the need for better understanding and classification of the disease.
research Emotional Consequences of Finasteride: Fool’s Gold
Finasteride can cause serious emotional side effects; doctors should check patients' mental health history before prescribing.