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Prdm1 is necessary for early whisker development in mice but not for other hair, and its absence changes nerve and brain patterns related to whiskers.

Edar signaling is crucial for controlling hair growth and regression.

Lack of Crif1 in hair follicle stem cells slows down hair growth in mice.

Sox2 controls hair color by affecting pigment production in hair follicles.

Mice can correct hair follicle orientation without certain genes, but proper overall alignment needs those genes.

Runx genes are important for stem cell regulation and their roles in aging and disease need more research.

Disrupting Acvr1b in mice causes severe hair loss and thicker skin.

Basal cell carcinoma mostly starts from cells in the upper skin layers, not hair follicle stem cells.

Super-enhancers controlled by pioneer factors like SOX9 are crucial for stem cell adaptability and identity.

Stem cell niches are crucial for regulating stem cell renewal and differentiation, and understanding them can help in developing regenerative therapies.

Lactate production is important for activating hair growth stem cells.

TGF-β is crucial for controlling stem cell behavior and changes in its signaling can lead to diseases like cancer.

New research suggests that skin cell renewal may not require a special type of cell previously thought to be essential.

Stem cells in the hair follicle are regulated by their surrounding environment, which is important for hair growth.

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

The document concludes that for hair and feather growth, it's better to target the environment around stem cells than the cells themselves.

Inactive hair follicle stem cells help prevent skin cancer.

Compartmentalized organization might be crucial for stem cells to effectively respond to growth or injury.

The extracellular matrix is crucial for controlling skin stem cell behavior and health.

Glutamine metabolism affects hair stem cell maintenance and their ability to change back to stem cells.

Fat cells are important for tissue repair and stem cell support in various body parts.

Hormones during pregnancy and lactation keep skin stem cells inactive, preventing hair growth.

Peptide hydrogel scaffolds help grow new hair follicles using stem cells.

New treatments targeting skin stem cells show promise for skin repair, anti-aging, and cancer therapy.

Stem cells and their surrounding environment in hair follicles work closely together, affecting hair growth and having implications for cancer and tissue regeneration.

Proper control of β-catenin activity is crucial for development and preventing diseases like cancer.

Ca_v1.2 affects hair growth and could be a target for hair loss treatments.

The environment around melanocyte stem cells is key for hair regeneration and color, with certain injuries affecting hair color and potential treatments for pigmentation disorders.

Gene network oscillations inside hair stem cells are key for hair growth regulation and could help treat hair loss.

Understanding hair follicle biology and stem cell control could lead to new hair loss treatments.