120 citations
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April 2009 in “Food Chemistry” This review examines the pharmacological evidence and bioactive compounds in Hibiscus plants, supporting their potential importance for developing treatments for chronic and degenerative diseases, though more research is needed.
34 citations
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December 2015 in “Neuroscience & Biobehavioral Reviews” In this study, several compounds, including estrogen and Dutasteride, showed neuroprotective effects on dopaminergic neurons in an MPTP mouse model of Parkinson's disease.
34 citations
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October 1994 in “Journal of Pharmaceutical Sciences” This study found that increasing the proportion of ethanol in minoxidil formulations improved skin penetration in both in vitro and in vivo tests on mice.
19 citations
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October 2017 in “European Journal of Pharmaceutics and Biopharmaceutics” This study found that the MXD/HP-β-CD GEL formulation promoted greater hair growth and improved gene expression related to hair growth in male rats compared to MXD solution or control groups.
6 citations
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December 2011 in “Drug Research” This study concluded that Flaxin tablets and the reference formulation are bioequivalent in terms of absorption rate and extent when administered as a single 5 mg dose to healthy male volunteers.
4 citations
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February 2017 in “Journal of Cutaneous Medicine and Surgery” This study assessed the dermatologic potential of western red cedar, white spruce, birch, balsam poplar, and black spruce used in First Nations medicine, highlighting several active compounds relevant to dermatology, but noted a lack of high-quality evidence in existing research.
4 citations
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January 2002 in “Indian Journal of Pharmaceutical Sciences” This study developed a precise and reproducible method for estimating finasteride in tablet formulations using a colorimetric reaction with specific reagents.
1 citations
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May 2025 in “The Journal of Phytopharmacology” This review identifies natural plants that possess androgen-related compounds, highlighting the potential of phytoandrogens as alternatives to allopathic treatments for conditions like hypogonadism, impotence, infertility, and erectile dysfunction.
1 citations
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September 2016 in “Acta Chromatographica” This study validated a new RP-HPLC method for accurately determining doxazosin mesylate and finasteride in bulk powders and capsule formulations.
July 2026 in “Clinical Cosmetic and Investigational Dermatology” In this study, a liposomal-encapsulated Sesbania grandiflora formulation significantly improved hair and scalp health in adults with hair loss over 180 days, showing enhanced hair density, thickness, growth rate, and tensile strength compared to placebo, with no related adverse events reported.
January 2024 in “Wiadomości Lekarskie” This study reports a successful combination treatment for phospho-organic compound poisoning, using standard therapy with atropine and toxogonin along with exogenous cholinesterases via blood transfusion, showing positive outcomes in patients whose endogenous cholinesterase levels dropped to 20%.
July 2022 in “Forte Journal” In this study, researchers tested hair tonic formulations with varying concentrations of bitter melon extract and found that higher concentrations enhanced hair growth in rabbits, with the 15% extract showing the greatest effect without causing skin irritation.
November 2021 in “International journal of life science and pharma research” This study reported that a solid lipid nanoparticle-based gel formulation, specifically optimized for psoriasis, improved drug loading capacity and release properties using high-pressure homogenization, suggesting its potential efficacy as a topical treatment.
This study found that a combination of photoprotector and nighttime formulations with essential oils improved skin barrier function and structural characteristics in young men's oily, acne-prone, and photoaged skin.
In this study, researchers found that cosmetic formulations containing guaraná extract effectively controlled oiliness in oily skin and hair by reducing sebaceous gland activity and lipid content without compromising skin barrier function, making them promising for managing excessive sebum production.
January 2020 in “International Journal of Research in Pharmacy and Chemistry” This study developed a validated HPLC method for accurately estimating dutasteride and its related compounds in capsules, suitable for routine and stability sample analysis.
December 2019 in “International journal of scientific research in science and technology” This study developed and validated a simple and cost-effective spectrophotometric method to accurately determine Aminexil in cosmetic formulations containing niacinamide and pyridoxine.
27 citations
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March 2024 in “Frontiers in Pharmacology” This review highlights the potential of natural product-derived compounds, such as flavonoids and alkaloids, to reverse multidrug resistance in tumors, emphasizing their role in regulating signaling pathways, proteins, and genes related to MDR, and aims to guide future research efforts in this area.
17 citations
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August 2007 in “Bioorganic & Medicinal Chemistry Letters” This study found that a specific amino-pyridine compound showed potent androgen receptor antagonist activity, stimulating hair growth in mice and reducing sebum production in a hamster model.
1 citations
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June 2023 in “International Journal of Pharmaceutical Sciences and Medicine” This review found that Sansevieria trifasciata contains numerous chemical compounds and has been traditionally used to treat various ailments, with prior studies confirming its pharmacological activities such as anti-ulcer, antibacterial, antioxidant, antidiabetic, and anticancer effects, among others.
March 2012 in “Daehan hwajangpum hakoeji/Daehan hwa'jangpum haghoeji” This study observed that a cream containing functional compounds from medicinal plants increased collagen production in human skin, while a hair tonic enhanced hair growth in mice.
43 citations
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October 2008 in “Indian Journal of Plastic Surgery” This narrative review explores the historical use and significance of cosmetics in ancient India, detailing various formulations and botanical ingredients documented in Ayurvedic texts, but it reports no new research findings.
68 citations
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March 2002 in “Journal of pharmaceutical sciences” This study found that nonionic liposomes were the most effective vehicle for delivering reporter genes into the skin of rat pups, compared to other liposome and nonliposome formulations.
32 citations
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November 2004 in “Journal of pharmaceutical sciences” This study quantifies the follicular uptake of tea tree oil in bovine udder skin, with microemulsion showing the highest concentration among different formulations tested.
18 citations
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January 2016 in “Elsevier eBooks” This chapter reviews nanotechnology in cosmetics, detailing various formulations, performance assessment methods, and evolving regulations, while discussing safety, stability, and effectiveness concerns; it reports no new experimental results.
12 citations
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August 2017 in “Archives of Pharmacal Research” In this study, lecithin-based microparticle formulations of minoxidil showed enhanced skin penetration and comparable hair growth effectiveness to commercial products in mice, while minimizing skin irritation often seen with standard minoxidil solutions.
August 2025 in “Fabad Journal of Pharmaceutical Sciences” This review highlights the potential medicinal benefits of Cuscuta reflexa, a parasitic plant known for its bioactive compounds, while emphasizing the need for further research to fully understand its therapeutic mechanisms and integrate its use into mainstream medicine.
November 2023 in “Borneo Journal of Pharmacy” In this study, researchers used scanning electron microscopy to analyze hair damage from 3% hydrogen peroxide and UVB radiation, observing that Caesalpinia sappan hair tonic formulations coated and interacted with the hair cuticle, potentially modifying hair fiber damage.
This research elucidates the molecular mechanisms underlying carbamazepine and griseofulvin's inclusion complex channel formations with polymers, revealing why carbamazepine forms stable channels independently, while griseofulvin requires polymeric support due to weaker interactions.
11 citations
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August 2007 in “Bioorganic & Medicinal Chemistry Letters” This study found that among the tested analogs, compound 4e was the most effective in inhibiting wax esters in vivo in the Golden Syrian hamster ear model.