research The Impact of AP Collagen Peptides on Hair Shaft Elasticity and Gloss: A Comprehensive Analysis
AP collagen peptides improve hair elasticity and gloss.
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research Identification of a Human Type XVII Collagen Fragment with High Capacity for Maintaining Skin Health
A fragment of human type XVII collagen shows great potential for skin health and wound healing.
research Revealing Novel Insights on How Oral Supplementation With Collagen Peptides May Prevent Hair Loss: Lessons From the Human Hair Follicle Organ Culture
Collagen peptides from marine and bovine sources may help prevent hair loss by affecting hair follicle stem cells differently.
research An Androgenetic Alopecia Remedy Based on Marine Collagen Peptide-Incorporated Dissolving Microneedles
New hair loss treatment using marine collagen and dissolvable needles improves hair growth.
research Alopecia in Patients with Collagen VI-Related Myopathies: A Novel Unrecognized Scalp Phenotype
People with Collagen VI-related myopathies may often have hair loss and scalp issues.
research Identification of Fetuin A as a Potential Modulator of Scar Formation
Fetuin A may increase collagen production and promote scarring.
research Editors' Picks
Collagen VII helps skin heal and stay strong, sirolimus may lower skin cancer risk in kidney transplant patients, high-molecular-mass hyaluronan helps naked mole rats resist cancer, dermal γδ T cells aid in hair growth in rodents, and overexpression of IL-33 in mouse skin causes itchiness, offering a model for studying allergic inflammation treatments.
research Synergistic Effect of Carbodiimide and Dehydrothermal Crosslinking on Acellular Dermal Matrix
Combining DHT and EDC improves the strength and stability of PADM scaffolds for tissue engineering.
research Hair Matrix Germinative Epidermal Cells Confer Follicle-Inducing Capabilities on Dermal Sheath and High Passage Papilla Cells
Hair growth can be stimulated by combining certain skin cells, which can rejuvenate old cells and cause them to specialize in hair follicle creation.
research The Effect of Menopause on the Skin and Other Connective Tissues
Menopause significantly reduces skin collagen, leading to thinner, less elastic skin, and hormone replacement may help but requires careful consideration.
research Expression of Matrix Metalloproteinases and Tissue Inhibitor of Matrix Metalloproteinases in the Hair Cycle
MMP-2 and MMP-9 help hair grow, while their inhibitors peak when hair growth slows.
research Matrix Metalloproteinase-9 Is Involved in the Regulation of Hair Canal Formation
MMP-9 is essential for proper hair canal formation.
research A Polymorphism in the Matrix Metalloproteinase-1 Gene Promoter Is Associated with the Presence of Polycystic Ovary Syndrome in Caucasian Women
A specific gene variation is linked to a higher risk of polycystic ovary syndrome in Caucasian women.
research Knockout of Integrin Beta1 in Induced Pluripotent Stem Cells Accelerates Skin-Wound Healing by Promoting Cell Migration in Extracellular Matrix
Turning off a specific gene in stem cells speeds up skin healing by helping cells move better.
research IGF1 and BM-MSC Incorporating Collagen-Chitosan Scaffolds Promote Wound Healing and Hair Follicle Regeneration
Adding insulin-like growth factor 1 and bone marrow-derived stem cells to a collagen-chitosan scaffold helps wounds heal faster and regrows hair follicles.
research Safety and Efficacy of CO2 Dot Matrix Laser Combined With Platelet-Rich Plasma on Depressed Scar After Acne Vulgaris and Influencing Factors of Its Repair Effect: A Retrospective Analysis
Combining CO2 laser with platelet-rich plasma is more effective for treating acne scars than laser alone.
research Keratin Promotes Differentiation of Keratinocytes Seeded on Collagen/Keratin Hydrogels
Keratin helps skin cells mature when added to a collagen mix, which could be important for skin and hair health.
research Collagen Involvement in Health, Disease, and Medicine
Collagen is crucial for health and treating certain diseases, and supplements can improve skin, nails, and hair conditions.
research AP Collagen Peptides (APCPs) Promote Hair Growth by Activating the GSK-3β/β-Catenin Pathway and Improve Hair Condition
AP collagen peptides help hair grow and improve hair health.
research AP Collagen Peptides Improve Hair Growth and Quality by Promoting Human Hair Cell Proliferation and Keratin Synthesis
AP collagen peptides may help hair grow better and become stronger.
research Low-Level Pulsed Wave Red Light Induces Type I Procollagen Protein and ATP Production at Shorter Treatment Times Compared to Continuous Wave Red Light
Pulsed red light boosts collagen and energy in cells faster than continuous red light.
research Effect of Ginsenoside Rd on Dermal-Epidermal Junction in Fibroblast
Ginsenoside Rd may help improve skin aging by increasing collagen in the skin.
research Abstract 82
Fetal scalp cells have more regenerative genes than adult cells, and decellularized muscle matrix is better for muscle repair than commercial alternatives.
research Hair-Growth-Promoting Effects of the Fish Collagen Peptide in Human Dermal Papilla Cells and C57BL/6 Mice Modulating Wnt/Beta-Catenin and BMP Signaling Pathways
Fish collagen peptides can significantly promote hair growth.
research Smart Bio-Polymeric Matrix for Accelerated Wound Healing and Tissue Regeneration
The material combining eggshell protein and scaffold helps wounds heal faster and regenerates tissue effectively.
research Type XVII collagen coordinates proliferation in the interfollicular epidermis
The study identified Type XVII collagen (COL17) as a crucial regulator of epidermal cell proliferation in the interfollicular epidermis (IFE) of both neonatal and aged mice. In neonatal mice, the absence of COL17 led to transient hyperproliferation due to disrupted Wnt signaling, which was reversible by replenishing COL17. In aged skin, loss of COL17 caused by inactive atypical protein kinase C signaling resulted in hyperproliferation, which could be suppressed by overexpressing human COL17. The research highlighted COL17's role in maintaining skin homeostasis and suggested its potential as a target for anti-aging treatments. However, the study faced limitations, including discrepancies between in vitro and in vivo results and a small sample size of patients with COL17A1 mutations, indicating a need for further investigation.
research Read-Through for Nonsense Mutations in Type XVII Collagen-Deficient Junctional Epidermolysis Bullosa
A new therapy for a skin blistering condition has not been developed yet.
research Author response: Type XVII collagen coordinates proliferation in the interfollicular epidermis
The study investigated the role of Type XVII collagen (COL17) in the interfollicular epidermis (IFE), focusing on its potential as an anti-aging molecule and its regulation of proliferation through Wnt signaling. It was found that loss of COL17 led to hyperproliferation and altered Wnt signaling, with aging also reducing COL17 levels and causing similar effects. However, reviewers noted concerns about the strength of the link between Wnt signaling and the observed phenotype, the transient nature of hyperproliferation in mice compared to humans, and speculative discussions on COL17's role in oncogenesis. Discrepancies between in vivo and in vitro findings were highlighted, and further validation was suggested to clarify these observations before publication.
research Decision letter: Type XVII collagen coordinates proliferation in the interfollicular epidermis
The study examined the role of Type XVII collagen (COL17) in the regulation of interfollicular epidermis (IFE) homeostasis and its connection to Wnt signaling, with implications for skin aging. It found that COL17 deficiency led to transient hyperproliferation in neonatal mice, which decreased over time, and suggested a potential anti-aging role for COL17. However, the study faced criticism for the weak link between Wnt signaling and the observed phenotype, the transient nature of hyperproliferation, and discrepancies between in vivo and in vitro findings. Despite its high quality, the study required further validation and additional experiments to strengthen its conclusions and clarify the role of COL17 in preventing oncogenesis.