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120-150 / 1000+ resultsresearch Fabricating the multibranch carboxyl-modified cellulose for hemorrhage control
This study found that modified microcrystalline cellulose with citric and ascorbic acid demonstrated enhanced hemostatic properties and biocompatibility in vitro and in animal hemorrhage models.
research ยาฉดไซโปรเทอโรนอะซเตทปลดปลอยนาน ชนดใชนำมนมะพราวผสมตวทำละลายเปนนำกระสายยา Cyproterone Acetate Sustained-Release Injection Using Mixed Coconut Oil/Solvent as Vehicle
The study found that cyproterone acetate could be released over 15 days using coconut oil mixed with certain wax inhibitors, though further safety studies are needed.
research Crystal Structure of Minoxidil
This structural study reports on the crystal properties of a compound used for treating alopecia, revealing different conformations and nitrogen hybridization in its piperidine rings.
research Use of Metformin versus Chromium Picolinate in the Management of Polycystic Ovarian Syndrome: A Randomized Controlled Clinical Trial
This study found that while there were no significant differences in ovulation and pregnancy rates, chromium picolinate was better tolerated than metformin in women with polycystic ovarian syndrome.
research Benzo[c]quinolizin-3-ones Theoretical Investigation: SAR Analysis and Application to Nontested Compounds
This study found that certain molecular quantum descriptors can be directly correlated with the biological activity of benzo[c]quinolizin-3-ones, potentially aiding in the identification and design of active compounds.
research Finasteride 98319‐26‐7
research Scientific Opinion on the safety of “coriander seed oil” as a Novel Food ingredient
The EFSA panel concluded that coriander seed oil is safe for use as a novel food ingredient at the proposed intake levels for healthy adults.
research A Simple Non-Invasive Approach toward Efficient Transdermal Drug Delivery Based on Biodegradable Particulate System
In this study, researchers introduced calcium carbonate-based carriers for transdermal drug delivery, observing efficient transport of substances and systemic absorption in rats, suggesting potential applications in regenerative medicine and dermatology beyond conventional topical treatments.
research Expression Pattern of Cyclooxygenase-2 in Normal Rat Epidermis and Pilosebaceous Unit during Hair Cycle
This study found that COX-2 expression in normal rat skin is linked to the hair cycle, with varying levels observed in different skin structures during anagen, catagen, and telogen phases.
research Hair cortisol/cortisone in combined oral contraceptive users: An exploratory analysis
This study suggests that using combined oral contraceptives does not increase hair glucocorticoid levels, but hair treatments should be considered as a confounder in stress biomarker assessments.
research Deoxycorticosterone’s anticonvulsant effects in infant rats are blocked by finasteride, but not by indomethacin
Finasteride blocks deoxycorticosterone's anticonvulsant effects in infant rats, but indomethacin doesn't.
research Pharmacological investigation of vitamin E with combined oral contraceptives on INHBA gene against PCOS that intricate through melatonin PKC pathway
This study assessed vitamin E and a combined oral contraceptive's impact on continuous light-induced PCOS in female rats, finding they reduced testosterone levels and modified oxidative stress, suggesting benefits via melatonin-related pathways.
research Three isostructural solvates of finasteride and their solid-state characterization
This study found that drying finasteride solvates at 85 °C for one day produced a metastable anhydrous form.
research Functionalization of Alkenes with Difluoromethyl Nitrile Oxide to Access the Difluoromethylated Derivatives
This study reports that difluoromethyl nitrile oxide can rapidly functionalize various alkenes at room temperature, leading to products that can transform into valuable medicinal chemistry building blocks like CF2H-isoxazolines for bioactive molecule modification.
research Polyphenolization:Hair Browning by Phenolic Adhesion,Ambient Oxygen, and Transition Metals
This study found that a synthetic polyphenol, dimeric 1,2,4-benzenetriol (diBTO), can coat gray hair and gradually oxidize, creating a resistant brown layer similar to apple browning, which offers a practical hair dyeing solution that withstands washing and reduces the need for long dyeing sessions.
research Three strands ironed closely together
In this study, researchers used iron ion coordination to successfully create a molecular knot with three organic ligand strands and eight crossings.
research Improved 2α-Hydroxylation Efficiency of Steroids by CYP154C2 Using Structure-Guided Rational Design
This study reported that structure-guided engineering of CYP154C2 mutants significantly improved the 2α-hydroxylation of androstenedione and testosterone, with enhanced conversion efficiency and substrate selectivity compared to the wild-type enzyme.
research Citrullus colocynthis (L.) Schrad. (Cucurbitaceae)
research Physicochemical Characterization and Evaluation of Castor Oil (R. communis) for Hair Biocosmetics
Castor oil is suitable for use in hair care products.
research Coconut oil works as a gonadal feedback testosterone booster and increases pituitary aromatase (cyp19a1b) expression levels in fugu (Takifugu rubripes)
Coconut oil boosts testosterone but doesn't fully trigger reproductive maturity in pufferfish.
research Accidental Poisoning with Autumn Crocus
This case report details a 43-year-old woman who survived severe multiorgan injury from accidental Colchicum autumnale poisoning, resulting in ongoing muscle weakness and intermittent hair loss three years after the incident.
research A comparative study of Fractional co2 laser combined with topical methotrexate versus Fractional co2 laser combined with topical [Calcipotriol + Betamethasone] in the treatment of nail psoriasis
This study found that both CO2 laser combined with topical methotrexate and calcipotriol plus betamethasone treatments improved nail psoriasis similarly, but some symptoms showed no improvement.
research The effect of Cotinus coggygria L. ethanol extract in the treatment of burn wounds
In this experimental study on Wistar albino rats, Cotinus coggygria leaf extract demonstrated potential as a treatment for burn-induced skin damage by reducing cytokine levels and promoting tissue healing.
research ROS Balance Autoregulating Core–Shell CeO2@ZIF-8/Au Nanoplatform for Wound Repair
In this study, researchers created a core-shell nanozyme, CeO2@ZIF-8/Au, which autonomously regulates ROS levels to efficiently eliminate bacteria, reduce inflammation, and promote wound healing by balancing ROS generation and scavenging in response to environmental conditions.
research Finasteride/spironolactone
research Molecular insights into the formation of drug-polymer inclusion complex
This study reports that carbamazepine can self-assemble into stable channel structures without guest polymers, while griseofulvin relies on guest molecules for structural stability in drug-polymer inclusion complexes.
research Coats' Plus: A Progressive Familial Syndrome of Bilateral Coats' Disease, Characteristic Cerebral Calcification, Leukoencephalopathy, Slow Pre- and Post-Natal Linear Growth and Defects of Bone Marrow and Integument
This article presents an update on a family with Coats' plus disorder, documenting additional symptoms and two new similar cases, and reviews literature suggesting a link to dyskeratosis congenita for potential molecular insights.
research Structural characterization of polymorphs and molecular complexes of finasteride
This study determined the molecular structure of finasteride and its related crystalline forms, highlighting different hydrogen-bond interactions and structural configurations in various crystalline complexes.
research Folate-cyclodextrin Conjugate for Targeted Chemotherapy
This study tested a folate-conjugate drug delivery system and found its cytotoxicity depends on whether the treated cells overexpress folate receptors, suggesting potential for targeted chemotherapy.