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This study identified PTEN as a key regulator in non-healing venous leg ulcers, suppressing immune responses and lymphangiogenesis, suggesting its potential as a therapeutic target for promoting VLU healing.

Non-classical 21 hydroxylase deficiency is an underdiagnosed cause of female hair loss and polycystic ovarian syndrome.

This study identified 21 novel circular RNAs in cashmere goats, with nine significantly more expressed during the anagen phase of hair follicle growth, suggesting roles in hair regeneration and cashmere yield enhancement.

In this study involving a mouse model, researchers reported that intranasal delivery of protein-based CRISPR/dCas9 nanoparticles targeting the gene *Sirt1* reduced cerebral edema and increased survival following ischemic stroke, with no significant toxicity observed.

This article discusses the aesthetic impact and primary treatment options for cutis verticis gyrata, but it reports no new clinical results.

This study found that skin organoids derived from iPSCs with an HS-associated NCSTN mutation showed defects in hair follicle stem cell differentiation and increased expression of inflammatory proteins related to hidradenitis suppurativa.

This study found that in vivo confocal scanning laser microscopy accurately quantifies neogenic hair follicles in mice, producing results similar to histology while avoiding fixation artifacts.

In this study, researchers developed an AI-powered platform called VitaDetect, which screens for vitamin deficiencies using image analysis of nails, tongue, and skin, aiming to provide an accessible and early-stage detection tool in resource-limited settings.

This review examines the epidemiology, pathophysiology, diagnosis, and management strategies for non-classic congenital hyperplasia due to 21-hydroxylase deficiency, and provides evidence-based recommendations for its treatment and genetic counseling.

This study developed a deep learning-based method that identified 3,620,516 potential drug-disease associations, suggesting a promising tool for large-scale virtual screening in drug research.

This special issue contains abstracts from the ASA 40th Annual Meeting, providing an overview of various studies without reporting new primary results.

This report presents a case of a seven-year-old girl with porokeratotic adnexal ostial nevus manifesting as hyperkeratotic verrucous papules on her left foot.

In this case study, a girl with hereditary vitamin D resistant rickets had a novel mutation in the VDR gene that affected hair cycling without causing total alopecia, suggesting ligand-independent VDR function in hair cycling.

This study investigated the effects of GFC with FGF5s and NMN at a depth of 0.8 mm using a microneedle for treating hair loss, but the abstract provides no measurable results.

This study suggests that the NGF/TrkA/CREB system plays a crucial role in promoting outer root sheath cell proliferation in cashmere goats, which may aid in marker-assisted breeding.

This study observed that the small molecules KY19382 and KY19334 inhibited cancerous traits in human cutaneous squamous cell carcinoma cells by suppressing the Wnt/β-catenin pathway, indicating their potential as treatments for cancers involving CDK1 overexpression and diseases related to CXXC5 accumulation.

In this case series, researchers reported an unexpectedly rapid and positive response to a topical, hydrogel-based botanical treatment for androgenetic alopecia in both male and female volunteers, achieving significant improvement in hair loss within 90 days instead of the planned 270 days.

A young woman's Cronkhite-Canada syndrome improved on its own after she gave birth.

This study suggests that finasteride may be a promising treatment for chronic central serous chorioretinopathy, but larger controlled trials are needed to confirm its efficacy.

In this study, researchers developed a custom-designed 3D-printed microscope stage insert for inverted confocal microscopes, enhancing the accessibility of long-term intravital imaging of live cell dynamics in live transgenic mice, particularly in the skin.

In this study of 20 female patients with Covid-19-induced persistent Telogen Effluvium, intra-dermal QR678 Neo® treatments led to significant reductions in hair fall and increases in hair growth and density, sustained even post-therapy.

This study found that cetirizine-loaded niosomal gels demonstrated superior skin deposition and retention compared to plain cetirizine gel, suggesting potential for improved topical management of alopecia.

In this study, 3D planned resection and reconstruction for skull defects after resection of cSCC with bony invasion led to accurate procedures, though patient-specific factors should guide treatment decisions.

The lotion CG428 did not show effectiveness in treating permanent hair loss in breast cancer survivors.

This article reports on a patient case of Cronkhite-Canada syndrome, detailing symptoms and diagnostic findings, and reviews the syndrome's characteristics without presenting new clinical data.

This study reported that immunotherapy in cancer patients can lead to skin-related immune adverse events, such as rashes, pruritus, and vitiligo, affecting a substantial proportion of patients.

This case report details a rare instance of a giant cellular blue nevus on the scalp, highlighting its potential to damage underlying bone and hair follicles, alongside a separate alopecia areata lesion successfully treated with topical corticosteroid.

This pilot study found that the Virtual Magic Wand program successfully educated dermatologists in problem-driven innovation, enhancing their ability to engage in innovative dermatologic practices.

This article describes a case of localized trichorrhexis nodosa in a patient with otherwise normal hair, highlighting the condition's response to trauma and diagnostic process but reporting no new clinical findings.

Carbon dioxide laser treatment effectively removed facial hair cysts without scarring or them coming back.