37 citations
,
June 2011 in “Journal of Cellular Biochemistry” In this study, transgenic male mice over-expressing the androgen receptor in mesenchymal stem cells showed reduced fat mass and improved glucose clearance, suggesting enhanced androgen sensitivity may alter body composition.
36 citations
,
June 2014 in “International Journal of Dermatology” This study suggests that dutasteride may be a viable alternative for Korean men with androgenetic alopecia who do not respond to finasteride, as it improved hair density and thickness in most participants.
36 citations
,
December 2002 in “Experimental dermatology” This study found that procyanidin B-3, a compound isolated from barley extract, may promote hair growth by enhancing hair epithelial cell growth and counteracting TGF-β1's growth-inhibiting effects in vitro and in vivo.
35 citations
,
October 2017 in “Signal Transduction and Targeted Therapy” This study found that fibromodulin significantly reduces scar formation and boosts scar strength in rodent and porcine models, suggesting potential for FMOD-based therapies in cutaneous wound repair.
35 citations
,
April 2014 in “Journal of proteomics” In this study, experimentally induced weight loss in merino sheep led to a decrease in wool fiber diameter and increased expression of certain high sulfur and glycine-tyrosine proteins, potentially impacting wool quality and industry preferences.
34 citations
,
January 2012 in “Journal of Dermatological Science” In this mouse study, researchers found that hydrogen peroxide and monoethanolamine in hair dyes may be key contributors to dermatitis and hair loss due to oxidative stress.
31 citations
,
September 2012 in “Human Brain Mapping” In this study, patients with seasonal affective disorder were found to have increased functional connectivity in certain brain networks and higher low-frequency fluctuations compared to healthy controls, which aligns with their attentional and psychomotor symptoms.
30 citations
,
March 2019 in “Archives animal breeding/Archiv für Tierzucht” In this study, variation in the KRTAP15-1 gene in goats was linked to changes in cashmere fibre diameter, with specific variants showing dominant or recessive effects.
30 citations
,
December 2014 in “Toxicological Research” This study found that 3% peppermint oil significantly enhanced hair growth in C57BL/6 mice, showing increased dermal thickness, follicle number, and follicle depth compared to other treatments.
30 citations
,
May 1999 in “Food and chemical toxicology” This study suggests that topical procyanidin B-2 is safe for use as a hair growth agent, as it showed no mutagenic effects or significant irritation in a series of toxicological tests.
29 citations
,
December 2003 in “Teratology” This case report describes fetal malformations and placental abnormalities in a pregnant woman who applied minoxidil topically, suggesting potential risks of its use during pregnancy.
29 citations
,
September 1990 in “Biochemical Journal” This study reports the purification of a specific sulphotransferase from rat liver that catalyzes the sulphation of minoxidil, potentially implicating it in minoxidil's bioactivation.
28 citations
,
January 2007 in “Journal of dermatology” This case report describes instances of lipedematous scalp and lipedematous alopecia in white adults, indicating these rare conditions may be more widespread and frequent in this population than previously thought.
27 citations
,
March 2022 in “Forensic Toxicology” This review discusses micro-segmental hair analysis for forensic toxicology, emphasizing its potential to provide detailed drug distribution profiles and its application in investigations, while noting the method's limitations and future perspectives.
25 citations
,
May 2020 in “Progress in Organic Coatings” This study found that bio-based waterborne polyurethanes derived from castor oil may offer effective hair-styling performance without skin irritation and appear to be safer for the environment compared to traditional hair sprays.
25 citations
,
November 2015 in “Journal of Ethnopharmacology” This study found that Cacumen platycladi extract significantly promoted hair growth and reduced dihydrotestosterone levels by inhibiting 5α-reductase activity in an androgen-sensitive mouse model.
25 citations
,
May 2014 in “Facial Plastic Surgery” In this study, intradermal injections of autologous platelet-rich fibrin matrix significantly increased hair density in patients with androgenetic alopecia at 2 and 3 months after initial treatment.
25 citations
,
January 2009 in “Oral and Maxillofacial Surgery Clinics of North America” This article reviews complications associated with modern hair transplant surgery and discusses their treatment and prevention but reports no new clinical results.
25 citations
,
June 2003 in “Journal of Investigative Dermatology Symposium Proceedings” This study found that among Japanese women with diffuse hair loss, decreased hair density without changes in vellus hair was the most common and distinct pattern observed, highlighting differences from previous observations in other populations.
23 citations
,
June 2018 in “Facial Plastic Surgery” This review suggests that platelet-rich plasma is a low-risk treatment for androgenic alopecia with good patient satisfaction and positive objective outcomes, but further research is needed to refine methods and standardize outcome measurements.
23 citations
,
January 2016 in “Theranostics” In this animal study, ultrasound combined with a new microbubble formulation of minoxidil increased hair growth rates and improved follicle characteristics more effectively than minoxidil alone.
22 citations
,
August 2011 in “Journal of Supercritical Fluids” In this study, fraction No. 3 of Oryza sativa bran extract demonstrated high unsaturated fatty acid content and significant 5α-reductase inhibition, suggesting potential for developing anti-androgenic alopecia products.
22 citations
,
November 2008 in “International Journal of Dermatology” This study suggests that a mixture of 5‐ALA and iron ion significantly improved hair growth in mice, comparable to minoxidil, without promoting keratinocyte or fibroblast proliferation in vitro.
21 citations
,
January 2003 in “Skin pharmacology and physiology” This study found that dutasteride completely suppressed the formation of 5alpha-dihydro metabolites in cultured human skin cells, suggesting its potential use in acne and androgenetic alopecia.
20 citations
,
November 2019 in “Biomolecules” This study found that finasteride impaired stress reactivity and reduced exploratory and impulsive behaviors in rats, potentially by altering the hypothalamus-pituitary-adrenal axis function.
19 citations
,
March 2018 in “Journal of Investigative Dermatology” This study indicates that transient Msx2 expression is critical for wound-induced hair follicle neogenesis, with distinct phases in the healing process essential for epidermal competence and hair regeneration.
19 citations
,
July 2017 in “PLoS ONE” This study suggests that passage number significantly affects in silico scratch assay results, highlighting the importance of reporting passage number for reproducibility in cell culture experiments.
19 citations
,
February 2017 in “Journal of radiation research” This study found that high-dose radiation can induce accelerated cellular senescence, inflammation, and loss of epithelial stem cells in mouse and human skin, contributing to radiation dermatitis.
19 citations
,
October 2014 in “Veterinary Dermatology” Dermoscopy is a good, noninvasive way to see normal cat skin structures and could be useful for check-ups.
19 citations
,
February 2012 in “International Journal of Urology” This review discusses gender identity disorder in Japan, highlighting the high prevalence and challenges in accessing appropriate treatment, and calls for wider understanding among medical professionals.