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New treatments targeting T-cell pathways are needed for better alopecia areata management.

A postmenopausal woman's excess male hormone symptoms improved after her ovaries were removed.

Alopecia areata and vitiligo share immune system dysfunction but differ in specific immune responses and affected areas.

Skin fat helps with body temperature control and has other active roles in health.

Human hair keratin might be good for filtering out harmful substances from water.

Mesenchymal stromal cells may help treat severe COVID-19, but more research is needed to confirm their effectiveness.

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

Regulatory T cells are essential for normal and improved wound healing in mice.

Leptin-deficient mice, used as a model for Type 2 Diabetes, have delayed wound healing due to impaired contraction and other dysfunctional cellular responses.

Mushroom-based scaffolds help heal skin wounds and regrow hair.

Keratinocytes help heal skin wounds by interacting with immune cells and producing substances that kill pathogens.

Human hair keratins can self-assemble and support cell growth, useful for biomedical applications.

Long COVID causes a wide range of long-lasting symptoms that change over time and are hard to diagnose and treat.

Liposomes show promise for delivering CRISPR for gene editing but face challenges like delivery efficiency and safety concerns.

Injectable platelet-rich fibrin may stop hair loss from Discoid lupus erythematosus.

Rare ULBP3 gene changes may raise the risk of Alopecia areata, a certain FAS gene deletion could cause a dysfunctional protein in an immune disorder, and having one copy of a specific genetic deletion is okay, but two copies cause sickle cell disease.

Keratinocytes and adipose-derived stem cells can effectively heal difficult skin wounds.

Stress may contribute to hair loss in alopecia areata by affecting immune responses and cell death in hair follicles.

New treatments for vitiligo may focus on protecting melanocyte stem cells from stress and targeting specific pathways involved in the condition.

Changes in keratin affect skin health and can lead to skin disorders like blistering diseases and psoriasis.

Histone modification is key in treating chronic inflammatory skin diseases.

Type 3 Innate Lymphoid Cells help maintain skin health and balance, and are involved in skin diseases and healing.

Skin stem cells are crucial for maintaining and repairing the skin and hair, using a complex mix of signals to do so.

The document concluded that more research is needed to find the best treatment for Frontal fibrosing alopecia.

Early treatment and regular check-ups are crucial for lupus patients to prevent progression and improve outcomes.

Using fat-derived stem cells with the drug meglumine antimoniate can help control skin disease and reduce parasites in mice with leishmaniasis.

Cellular and immunotherapies show promise for healing chronic wounds but need more research.

Natural products and phytochemicals may help with hair regrowth, but more research is needed.

Araliadiol may promote hair growth like minoxidil without being toxic.

The document explains how to create detailed biological pathways using genomic data and tools, with examples of hair and breast development.