research Cyclosporine A Increases Hair Follicle Growth by Suppressing Apoptosis-Inducing Factor Nuclear Translocation: A New Mechanism
Cyclosporine A helps hair grow by blocking a process that would otherwise cause hair cells to die.
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research Drug News and Therapeutic News
JAK inhibitors help treat some diseases but may increase risks of blood clots and cancer in certain patients.
research Development of a Non-Parametric Population Pharmacokinetics Model and Bayesian Estimator for Tacrolimus in Tunisian Renal Transplant Patients
The model and estimator can predict drug exposure in kidney transplant patients well.
research Hair Dermal Papilla Cell Metabolism Is Influenced by Minoxidil
research The Role of Hair Follicles in the Percutaneous Absorption of Caffeine
Hair follicles significantly increase the speed and amount of caffeine absorbed through the skin.
research Hair Follicles Contribute Significantly to Penetration Through Human Skin Only Shortly After Application as a Solvent Deposited Solid in Humans
Hair follicles greatly increase caffeine absorption through the skin shortly after it's applied.
research Risk of Meningioma Among Users of High Doses of Cyproterone Acetate Compared With the General Population: Evidence From a Population-Based Cohort Study
High doses of cyproterone acetate are linked to an increased risk of developing meningioma.
research Permeation of Topically Applied Caffeine Through Human Skin – A Comparison of In Vivo and In Vitro Data
Caffeine penetrates human skin in lab tests similarly to real-life conditions, but actual skin use is still essential for accurate results.
research A Novel Finasteride 0.25% Topical Solution for Androgenetic Alopecia: Pharmacokinetics and Effects on Plasma Androgen Levels in Healthy Male Volunteers
New finasteride solution effectively reduces baldness-causing hormone, potentially with fewer side effects.
research Topical Minoxidil: Cardiac Effects in Bald Men
Using topical minoxidil for baldness can cause heart problems, especially in those with heart disease.
research Effects of a Novel Finasteride 0.25% Topical Solution on Scalp and Serum Dihydrotestosterone in Healthy Men with Androgenetic Alopecia
The 0.25% finasteride solution, when applied once a day, effectively reduces scalp DHT, potentially minimizing sexual side-effects linked to a systemic DHT reduction.
research Using a Capture–Recapture Method to Assess the Frequency of Adverse Drug Reactions in a French University Hospital
The study found that combining different databases gives a better estimate of drug side effects in hospitals.
research Treatment of Severe Hypertension with Minoxidil: Advantages and Limitations
Minoxidil effectively controls blood pressure but side effects may limit its use.
research Valproic Acid Reduces Hair Loss and Improves Survival in Patients Receiving Temozolomide-Based Radiation Therapy for High-Grade Glioma
Valproic acid helps delay hair loss and increases survival time for high-grade glioma patients undergoing radiation therapy.
research The Pharmacokinetics of 2.5- to 10-mg Oral Doses of Minoxidil in Healthy Volunteers
This document studied minoxidil in healthy volunteers. Minoxidil is quickly absorbed and eliminated from the body.
research Safety Profile of Human Papilloma Virus Vaccines: An Analysis of the US Vaccine Adverse Event Reporting System from 2007 to 2017
HPV vaccines are generally safe but need further investigation for rare side effects.
research Finasteride Use and Acute Pancreatitis in Taiwan
No clear link between finasteride use and acute pancreatitis risk.
research Finasteride, A Steroid 5α-Reductase Inhibitor, Does Not Affect the Oxidative Metabolism of Antipyrine
Finasteride doesn't affect antipyrine metabolism, so interactions with cytochrome P-450 enzyme drugs are unlikely.
research Rivaroxaban-Induced Hair Loss
Rivaroxaban may cause hair loss.
research Minoxidil Sulphation in Human Liver and Platelets
Minoxidil is processed in the body by an enzyme found in the liver and platelets.
research Finasteride 1 mg Has No Inhibitory Effect on Omeprazole Metabolism in Extensive and Poor Metabolizers for CYP2C19 in Japanese
Finasteride doesn't affect omeprazole metabolism in Japanese people.
research Contraindicated Use of 5-Alpha-Reductase Inhibitors in Women
The document concludes that women should not use 5-alpha-reductase inhibitors due to the risk of birth defects and limited effectiveness.
research Unlocking the Potential of the Secretome in Hair Growth Enhancement
Secretome-based therapies could improve hair growth better than current treatments.
research Formulation and Evaluation of Herbal Hair Serum: A Review
Herbal hair serum promotes natural hair growth and maintains healthy hair.
research Therapeutic Effects of Topical Cetirizine in the Treatment of Female Pattern Hair Loss: A Randomized Controlled Noninferiority Trial
Cetirizine lotion can effectively treat female pattern hair loss.
research Are All Adverse Effects Undesirable? A Case of Chemotherapy-Induced Adverse Effect - An Exception!
Excessive eyelash growth from erlotinib may indicate positive tumor response and help treat madarosis.
research A Randomized, Open Label Comparative Study of Hydroxychloroquine with Betamethasone Oral Mini Pulse in the Management of Patients with Alopecia Areata
Hydroxychloroquine is less effective than betamethasone oral mini pulse therapy for treating alopecia areata.
research The Effect of Testosterone and Fleece-Flower Root on Mouse Hair
Testosterone and fleece-flower root affect mouse hair growth.
research Impaired Cardiometabolic Effects of Bromocriptine in Men With Early-Onset Androgenic Alopecia
Men with early-onset hair loss have less cardiometabolic benefit from bromocriptine.
research Pituitary Effects of Metformin in Men With Early-Onset Androgenic Alopecia
Metformin reduces certain hormone levels in men with early-onset hair loss.