Systemic Lupus Erythematosus and Vitamin D Deficiency in an Adult Sudanese Patient with Sickle Cell Trait

January 2021 in “ International journal of medical science and health research ”

Monzer Hassan Balla Mustafa

hair loss skin rash antibodies vitamin D deficiency systemic lupus erythematous autoimmune diseases SLE ANA

TLDR A patient with sickle cell trait and low vitamin D might have lupus, a rare combination that needs more attention.

The document discusses a case of a patient with sickle cell trait who presented with various symptoms including skin rash, palpitations, constipation, recurrent headaches, joint pain, fatigue, hair loss, and a sensation of heat despite normal body temperature. The patient was found to have a positive antinuclear antibody (ANA) test and a low level of vitamin D, which led to the suspicion of systemic lupus erythematous (SLE). The case highlights the rarity of SLE in patients with sickle cell trait and suggests that more attention should be given to the potential association between autoimmune diseases and sickle cell trait, not just sickle cell disease.

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