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Stress activates a special function of the Vitamin D receptor with the help of c-Jun, which can also prevent cell death.

The vitamin D receptor can act without its usual activating molecule, affecting hair growth and skin cancer, but its full range of actions is not well understood.

Vitamin D is important for bones, hair, blood pressure, and breast development.

The vitamin D receptor is involved in multiple body functions beyond calcium regulation, including immune response and rapid reactions not related to gene activity.

Removing part of the vitamin D receptor stops vitamin D from working properly.

The vitamin D receptor has many roles in the body beyond managing calcium, affecting the immune system, hair growth, muscles, fat, bone marrow, and cancer cells.

Most Hairless gene mutations reduce its ability to work with the Vitamin D Receptor, which might explain a certain type of hair loss.

ΔNp63α helps control a protein that stops cancer cells from spreading.

Vitamin D boosts a specific gene activity in kidney cells that could improve heart and kidney function.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

The vitamin D receptor helps maintain hair and bone health even without binding vitamin D.

Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.

NcoA4 may have roles beyond helping control gene activity, possibly affecting cell behavior and stability.

Hormones and their receptors, especially androgens, play a key role in hair growth and disorders like baldness.

A Chinese family had a child with a specific gene mutation causing vitamin D-resistant rickets, but the child improved with calcium and low-dose calcitriol.

Some vitamin D analogs can thicken skin and reduce pore size like a common acne treatment, with one analog also affecting skin growth factors.

SOX9 helps determine stem cell roles by interacting with DNA and proteins that control gene activity.

Vitamin D receptor interacts with certain dietary components to help prevent diseases and regulate hair growth.

LEF1 interacts with Vitamin D Receptor, affecting hair follicle regeneration and this could be linked to hair loss conditions.

Oral tofacitinib significantly improves lichen planopilaris symptoms without adverse effects.

Genetic research has advanced our understanding of skin diseases, but complex conditions require an integrative approach for deeper insight.

Topical patidegib gel effectively treats basal cell carcinoma in Gorlin syndrome patients without causing the side effects seen with oral treatments.

Modulating Cytochrome P450 activity could help develop new skin disease treatments.

Two rare genetic diseases cause severe rickets in children due to defects in vitamin D metabolism.

Mutations in the vitamin D receptor cause hereditary vitamin D-resistant rickets, leading to poor bone health and requiring high calcium doses for treatment.

RXRα is crucial for proper immune response and links diet to immune function.

The enzyme sEH is important for hair growth and its inhibition could help treat hair loss.

Hair growth and health are influenced by factors like age, environment, and nutrition, and are controlled by various molecular pathways. Red light can promote hair growth, and understanding these processes can help treat hair-related diseases.

Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.

Hair follicles are complex, dynamic mini-organs that help us understand cell growth, death, migration, and differentiation, as well as tissue regeneration and tumor biology.