February 2020 in “VSNU Open Access deal” This study established age-adjusted reference intervals for hair cortisol in children from birth to 18 years, finding higher cortisol levels in infants possibly linked to slower hair growth.
23 citations
,
February 1979 in “Veterinary Clinics of North America: Small Animal Practice” This review discusses the physicochemical properties, binding mechanisms, and factors affecting corticosteroid-binding globulin (CBG) functions, but reports no new clinical results.
13 citations
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July 2018 in “General and comparative endocrinology” This study observed that direct exposure to androgens in Western clawed frogs differentially affects thyroid receptor and deiodinase gene expression in male and female tissues, offering insight into sex-specific metabolic pathway activation.
August 2022 in “IntechOpen eBooks” This article reviews congenital adrenal hyperplasia, a group of rare genetic disorders affecting steroid synthesis, and highlights the need for specific therapy and ongoing monitoring, but reports no new clinical findings.
This study found low concordance between distal and proximal hair cortisol concentrations during early pregnancy, particularly when measured with different assay methods.
3 citations
,
January 1996 in “Journal of Dermatological Treatment” In this study, twice daily application of 3 μg/g calcitriol ointment was reported to be safe, effective, and well tolerated for treating moderate to severe chronic plaque psoriasis on the face and surrounding areas.
November 2015 in “Journal of the Korea Academia-Industrial cooperation Society” This study established a stable cell line for CRF1 receptor screening, which can be used to develop functional cosmetics and modulators potentially affecting hair re-growth.
This abstract reviews the use of spironolactone as a treatment for hormonal acne, female pattern hair loss, and hirsutism due to its antiandrogenic properties and favorable side effect profile, highlighting its value in dermatological therapies.
April 2019 in “Journal of Investigative Dermatology” In this study, engineered mice with a mutation similar to that in Olmsted syndrome showed progressive hair loss due to impaired inner root sheath keratinocyte differentiation and stem cell exhaustion.
May 2026 in “The Knowledge Bank (The Ohio State University)” This study observed significantly higher hair cortisol concentrations in foals compared to mares, with a strong positive correlation between the two, suggesting that hair cortisol can reflect maternal and fetal cortisol exposure during the last trimester of gestation in horses.
248 citations
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December 2011 in “Journal of Neuroscience” This study demonstrated that stress-derived neurosteroid THDOC shifts from inhibiting to activating the HPA axis under stress, presenting potential therapeutic targets for stress-related disorders.
1 citations
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September 2021 in “Dermatologic Therapy” In this observational study, AC5 reduced hair loss in 89% of subjects with mild androgenic alopecia, and was well tolerated and appreciated by most participants.
87 citations
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April 1973 in “Endocrinology” This study found that in hamster flank organs, 17βC inhibited enlargement caused by topical testosterone but not by DHT, suggesting potential use in androgen-related skin disorders like acne.
32 citations
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October 2003 This review reports that 100 mg/day spironolactone improved hair growth more than placebo and was more effective in reducing hair growth than finasteride and low-dose cyproterone acetate, but its effectiveness for acne remains unclear due to small sample sizes.
13 citations
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November 2010 in “Experimental Dermatology” This study found that L-ascorbic acid 2-phosphate could reduce DHT-induced DKK-1 expression in balding scalp cells, suggesting potential for treating androgen-driven hair loss.
9 citations
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November 1980 in “Geburtshilfe und Frauenheilkunde” In this study, prolonged intravenous Fenoterol infusion was associated with intensive hair growth in most patients, although hormonal changes typically linked to such effects were not observed.
This study undertook a retrospective chart review to examine the link between the severity of female pattern hair loss and abnormal cholesterol levels in patients from a specialty alopecia clinic, but results are not reported.
April 2023 in “Journal of Investigative Dermatology” This study found that recombinant type III collagen may aid skin aging management by promoting fibroblast proliferation and migration, with a modest impact on inflammatory marker IL-6, though it did not significantly affect TNF-a secretion in vitro.
3 citations
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June 2020 in “Journal of Dermatological Treatment” In this study, researchers found that triamcinolone acetonide provided earlier visual improvement in alopecia areata treatment, but by 12 weeks, both triamcinolone acetonide and betamethasone 1.75 mg/ml showed similar effectiveness compared to lower-dose betamethasone and placebo.
June 2025 in “International Journal of Applied Pharmaceutics” This study developed a testosterone-induced androgenetic alopecia model in BALB/c mice, finding that a 0.075 ml testosterone injection best replicated the dermal and hair follicle conditions of AGA patients, providing a promising tool for future drug testing and research into AGA therapies.
9 citations
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June 2020 in “BMC Molecular and Cell Biology” This study found that stress hormones, particularly CRF, can inhibit hair growth and induce hair loss by affecting human dermal papilla cells and hair follicles, suggesting a functional HPA axis in these cells.
August 1993 in “Journal of Dermatological Science” Testosterone metabolism in balding scalp cells may not be the main cause of hair loss.
62 citations
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December 1994 in “Journal of Endocrinology/Journal of endocrinology” In this study, administrating ovine prolactin accelerated secondary hair follicle reactivation and moulting in cashmere goats, while bromocriptine delayed these processes.
11 citations
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September 2015 in “Theriogenology” Testosterone boosts fluid and electrolyte secretion in seminal vesicles, aiding sperm function.
88 citations
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September 2003 in “Clinical endocrinology” This review discusses the diagnosis, management, and hormone treatment of transsexual individuals, and examines the risks and effects of cross-sex hormone therapy without presenting new clinical results.
65 citations
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December 1986 in “The Journal of Clinical Endocrinology & Metabolism” This study concluded that a 26-year-old woman had autosomal dominantly inherited hereditary cortisol insensitivity, leading to increased adrenocortical cortisol and androgen secretion, which caused clinical symptoms unlike in her male relatives.
January 2017 in “Elsevier eBooks” Congenital Adrenal Hyperplasia is mainly caused by enzyme deficiencies, leading to varying symptoms like hormone imbalances and physical changes.
April 2020 in “Journal of the Endocrine Society” This case report emphasizes the importance of recognizing non-classic congenital adrenal hyperplasia as a cause of hyperandrogenism and the need for genetic counseling given potential familial implications.
17 citations
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August 1967 in “JAMA” In this study, a plasma-fluorescent corticoid test effectively differentiated patients with adrenal insufficiency from those with normal adrenal function based on their response to corticotropin.