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This study found that K15 is variably expressed in sheep and mouse hair follicles, with specific patterns suggesting a role in the early stages of keratinocyte differentiation.

This study suggests that Keratin 15 expression in stratified epithelia may be regulated by two distinct mechanisms involving PKC/AP-1 pathway for differentiation and FOXM1 for basal cells, challenging its reliability as a sole stem cell marker.

This review evaluates existing research on Keratin 15 to assess its validity as a marker for epidermal stem cells, reporting no new results.

This study found that knock-down of keratin 15 in various cell lines affected cell spreading, morphology, migration, differentiation, and proliferation, suggesting its role in maintaining the stem cell nature of keratinocytes.

This study proposes a model suggesting that the ratio of keratin 15 to keratin 14 in epidermal keratinocytes promotes a progenitor state and opposes differentiation, based on insights from both cell culture and transgenic mouse models.

This study found that keratin 15 lacks the ability to sequester YAP1 in keratinocytes effectively, unlike keratin 14, and suggests that a higher K15:K14 ratio may promote a progenitor state and inhibit differentiation in epidermal keratinocytes.

This study found that keratin 15 expression is downregulated in hyperproliferative conditions like psoriasis and hypertrophic scars, suggesting it is not compatible with keratinocyte activation.

This study measured the lengths and depths of different portions of occipital scalp hair follicles and suggested cutting below 1 mm for hair regeneration procedures to avoid damaging the bulge zone.

The K15 promoter effectively targets stem cells in the hair follicle bulge.

This study demonstrated that HOXC13 directly influences hair keratin gene expression by binding to specific DNA motifs, suggesting its role in early hair follicle differentiation.

This study identified a radio-resistant population of Krt15+ stem cells in the mouse small intestine that can initiate tumors, suggesting potential targets for colon cancer therapy.

This study characterized the intron-exon organization of human keratin 15 and keratin 19 genes to aid future mutation detection analyses related to potential genetic disorders of keratinization.

This study found that the unique functions of keratin 16 are likely determined by its tail domain, challenging the previous hypothesis about the role of the helix 1B subdomain.

This study found that as few as 90 base pairs of the K5 promoter directed keratinocyte-preferred expression in stratified epithelia, especially in epidermis, hair follicles, and tongue, showing cell type specificity.

This review discusses the role of stem cells in alopecia pathogenesis, highlighting the differences between scarring and nonscarring types, and reports no new clinical results.

This study identified a specific subpopulation of hair follicle stem cells in mice and humans that are essential for long-term hair regeneration, highlighting the potential for regenerative therapy.

This study suggests that cultured human hair follicle cells can potentially recreate epidermis and produce bioengineered hair follicles in a GMP cell factory for regenerative therapy in alopecia.

In this study, growing human hair follicles in a defined glycosaminoglycan hydrogel ex vivo promoted cell survival, proliferation, and activation of hair growth-related signaling pathways, suggesting GAG-based hydrogels could modulate the hair follicle growth cycle.

This review outlines the clinical and histopathological features that aid in classifying tumors arising from the folliculosebaceous apparatus and reports no new research results.

This article discusses the complex biological functions and social significance of hair follicles and reports no new research findings, emphasizing their role in health, disease, and a substantial beauty industry.

This study observed similar D2-40 expression in scarring and nonscarring alopecia, with some increase in scarring cases, suggesting possible Fos-dependent mechanisms, though more research is needed for definitive conclusions.

In this study, one type of commercial culture medium supported expression of stem cell markers in hair follicle epithelial stem cells, but their differentiation potential and hair follicle-inducing ability declined over time.

This study found that topical application of metformin significantly enhanced skin regeneration in mechanically stretched skin in rats, likely by boosting the proliferation of skin-derived stem cells.

This study identified a small population of PAX3+/CD34+ cells in human foreskin tissue that may serve as transition cells between melanocyte stem cells and hair follicle stem cells, characterized by specific marker expressions.

This study found that a novel 15% topical minoxidil solution achieved a clinically significant hair regrowth response in 60% of women with female pattern hair loss who did not respond to 5% minoxidil, without increasing adverse events.

This case report describes a hybrid cyst in a Sprague-Dawley rat, showing both infundibular and matrical differentiation similar to different parts of normal hair follicles.

This study found that water extract of olive leaf may enhance markers linked to epidermal and dermal stem cell activity and potentially improve skin aging, especially in individuals who do not exercise regularly.

This study found that SesZen-Bio TM, a proprietary extract from Sesbania grandiflora leaves, increased proliferation of hair cells and hair shaft length in vitro and ex vivo, potentially due to activation of the Wnt/β-catenin signaling and stem cell differentiation pathways.

This study reports a new optimized protocol for isolating and labeling single cells from neonatal mouse skin, enabling high-quality single cell RNA sequencing for lineage-specific cell analysis.