January 2009 in “Indian Journal of Plastic Surgery” Surgical methods for hair loss due to scarring should be chosen based on the size, location, and shape of the area, with most patients seeing good results.
Dense-packing hair grafting is a simple, safe, and effective way to restore hair in people with cicatricial alopecia.
April 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” Targeting cholesterol, fatty acids, fibrosis, and mast cells may help treat CCCA.
June 2020 in “Journal of Investigative Dermatology” Leukocyte-rich platelet-rich plasma is safe and can potentially help treat scarring hair loss.
September 2009 in “Hair transplant forum international” A committee was formed to improve hair restoration for certain hair diseases by collecting and analyzing data.
June 2007 in “Journal of Investigative Dermatology” Title change to "Central Centrifugal Cicatricial Alopecia (CCCA)"; common in African American women; hair-grooming methods may contribute; no effective therapy found; trials needed.
44 citations,
November 2011 in “The Journal of Dermatology” New understanding of the causes of primary cicatricial alopecia has led to better diagnosis and potential new treatments.
42 citations,
January 2008 in “SKINmed/Skinmed” The article explains how to diagnose and manage certain types of scarring hair loss.
30 citations,
November 2013 in “Journal of The American Academy of Dermatology” Elastin staining helps assess late-stage scarring alopecia but is not definitive, and clinical diagnosis is still crucial.
20 citations,
July 2008 in “Dermatologic Therapy” The document says that treating the root cause of hair follicle damage is crucial to prevent permanent hair loss, and treatment options vary.
15 citations,
February 2003 in “British Journal of Dermatology” The study suggests computer-assisted analysis of scalp biopsies could improve hair loss diagnosis but needs more validation.
14 citations,
October 2018 in “PloS one” Deleting the Far2 gene in mice causes sebaceous gland issues and patchy hair loss.
12 citations,
January 2016 in “Skin appendage disorders” Hair restoration surgery can potentially treat primary scarring alopecias, but it's important to start early medication, ensure patient remission before transplant, and monitor after surgery.
12 citations,
June 2015 in “Dermatology Reports” Middle-aged women in Iran are most affected by primary cicatricial alopecia, especially discoid lupus erythematous.
2 citations,
January 2021 in “Przegląd Dermatologiczny (1959)” The article discusses various treatments for different types of non-scarring hair loss.
March 2024 in “Journal of Investigative Dermatology” People with Primary Cicatricial Alopecia have a higher risk of heart disease.
September 2023 in “Medicina-lithuania” The study suggests that analyzing DNA can help treat hair loss, but more research is needed.
August 2021 in “Al-Azhar International Medical Journal (Print)” Hair transplantation is effective for treating cicatricial alopecia with fewer anesthesia risks, scars, and recovery time.
March 2021 in “CRC Press eBooks” The document concludes that different patterns of hair thickness and scalp changes can help diagnose types of non-scarring hair loss.
January 2020 in “JAAD case reports” Systemic mastocytosis may cause a type of hair loss called cicatricial alopecia.
December 2012 in “Drugs & Therapy Perspectives” Doctors use their experience to choose treatments for scarring hair loss because it's hard to diagnose and treat.
June 2008 in “Springer eBooks” The document concludes that permanent hair loss conditions are complex, require early specific treatments, and "secondary permanent alopecias" might be a more accurate term than "secondary cicatricial alopecia."
November 2022 in “Frontiers in Medicine” PRP shows promise for treating mild alopecia areata but needs more research for cicatricial alopecias.
December 2020 in “Journal of Endocrinology and Reproduction” Certain inflammatory molecules and leptin may contribute to hair loss in cicatricial alopecia.
150 citations,
October 2010 in “The American Journal of Pathology” The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.
95 citations,
February 2019 in “The New England Journal of Medicine” Mutations in the PADI3 gene are linked to a higher risk of scarring hair loss in women of African descent.
95 citations,
November 2016 in “Journal of The American Academy of Dermatology” Treatments for permanent hair loss from scarring aim to stop further loss, not regrow hair, and vary by condition, with partial success common.
88 citations,
April 2011 in “Archives of Dermatology” Type 2 diabetes, bacterial scalp infections, and tight hairstyles like braids and weaves are linked to a higher risk of a scarring hair loss condition in African American women.
75 citations,
March 2009 in “Journal of The American Academy of Dermatology” CCCA is a hair loss type affecting African women, possibly caused by grooming and chemicals, with various treatments and needing more research.
65 citations,
November 2016 in “Journal of The American Academy of Dermatology” The document concludes that early recognition and treatment of primary cicatricial alopecia is crucial to prevent permanent hair loss.