research Patchy Hair Loss, Hyperpigmented Plaques, and Hyperkeratotic Papules in a Middle-Aged Woman
The patient responded well to treatment with no disease progression.
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540-570 / 1000+ results research Lichen Planopilaris Is Characterized By Immune Privilege Collapse Of The Hair Follicle's Epithelial Stem Cell Niche
The study investigated the pathogenesis of lichen planopilaris (LPP), a chronic inflammatory disease causing permanent hair loss, by analyzing scalp biopsies from 42 adult patients. It found that LPP is characterized by the collapse of immune privilege in the hair follicle's epithelial stem cell niche, known as the bulge. This collapse was evidenced by increased expression of MHC class I and II and a Th1-biased cytotoxic T cell response, alongside increased proliferation and apoptosis of epithelial hair follicle stem cells (eHFSCs). The findings suggested that interferon-γ (IFNγ) plays a significant role in this process, indicating that LPP may be an autoimmune disease. The study proposed that protecting or restoring immune privilege in the bulge could be a therapeutic strategy for managing this treatment-resistant form of cicatricial alopecia.
research Effects of Chemical Straighteners on the Hair Shaft and Scalp
Chemical hair straighteners can cause scalp and hair damage, but long-term effects are unclear.
research The Role of PPARγ-Mediated Signalling in Skin Biology and Pathology: New Targets and Opportunities for Clinical Dermatology
PPARγ is crucial for skin health but can have both beneficial and harmful effects.
research Dissecting Cellulitis of the Scalp in a Pediatric Male
A 13-year-old boy with a rare scalp condition improved significantly with isotretinoin, minoxidil, oral steroids, and antiseptic shampoo.
research A Systematic Approach to Afro-Textured Hair Disorders
Dermatoscopy helps diagnose hair and scalp disorders in people with Afro-textured hair, but more research is needed for better understanding and treatment.
research Updates in the Understanding and Treatments of Skin and Hair Disorders in Women of Color
New treatments for skin and hair disorders in women of color address unique biological differences and include specific acne medications, sunscreens, skin lighteners, and hair care adjustments.
research Advances and Challenges in Hair Restoration of Curly Afrocentric Hair
Specialized techniques are needed for hair restoration in individuals with curly Afrocentric hair due to unique challenges.
research Case Report: Rowell Syndrome-Like Flare of Cutaneous Lupus Erythematosus Following COVID-19 Infection
COVID-19 may trigger severe skin flare-ups in people with autoimmune conditions like lupus.
research Acne Necrotica (Varioliformis) – Case Report
A rare skin condition causing scarring was successfully treated with topical erythromycin and benzoyl peroxide.
research Skin and Hair Cosmetic Issues in Women of Color
A scarring hair loss condition mainly affects middle-aged women of African descent, impacting their quality of life, with treatments more effective when started early.
research Psoriatic Scarring Alopecia: A Case Report
A woman with long-term scalp psoriasis developed rare scarring hair loss that didn't fully respond to treatments.
research Discoid Lupus Alopecia Complicated by Frontal Fibrosing Alopecia on a Background of Androgenetic Alopecia
Woman has discoid lupus, frontal fibrosing, and androgenetic alopecia.
research Clinical Study of Fibrosing Alopecia in a Pattern Distribution in a Latin American Population
The study found that treatment improved hair condition in patients with Fibrosing Alopecia in a Pattern Distribution in Chile.
research Differential Expression of mTOR Signaling Pathway Proteins in Lichen Planopilaris and Frontal Fibrosing Alopecia
The mTOR pathway proteins are altered in the hair follicles of patients with Lichen Planopilaris and Frontal Fibrosing Alopecia.
research Case of Alopecia Universalis Accompanied by Minimal Change Nephrotic Syndrome
A possible link exists between minimal change nephrotic syndrome and complete hair loss.
research Frontal Fibrosing Alopecia: Clinical Features, Diagnosis, and Treatment Challenges
Frontal Fibrosing Alopecia is a type of hair loss affecting mostly older women, with no agreed best treatment.
research Scalp Alopecias in Richly Pigmented Patients
Hair care practices like using relaxers and tight braiding can lead to permanent hair loss in black women.
research A Case of Folliculitis Decalvans With Concomitant Acne Keloidalis Nuchae, Androgenic Alopecia, and Profound Postinflammatory Hyperpigmentation
A 37-year-old man with hair loss and skin issues was successfully treated with oral antibiotics, highlighting the need for early treatment. Long-term care includes low-dose antibiotics and avoiding caps and wigs.
research Frontal Fibrosing Alopecia in Postmenopausal Women
Some postmenopausal women with frontal fibrosing alopecia stopped losing hair with finasteride treatment, hinting at a possible hormonal cause.
research Trichoscopy in Alopecias: Diagnosis Simplified
Trichoscopy is a useful, non-invasive way to diagnose different types of hair loss.
research The Histopathology of Noncicatricial Alopecia
Different types of hair loss have unique features under a microscope, but a doctor's exam is important for accurate diagnosis.
research Acquired Scalp Alopecia: A Review
Early diagnosis and treatment are crucial for preventing permanent hair loss in various scalp conditions, and while new treatments are promising, more research is needed to evaluate their effectiveness.
research Tinea Capitis Mimicking Dissecting Cellulitis of the Scalp: A Histopathologic Pitfall When Evaluating Alopecia in the Post-Pubertal Patient
A fungal infection can look like a different scalp condition in teens, leading to wrong treatment until proper tests are done.
research Stem Cells and Alopecia: A Review of Pathogenesis
Damaged hair follicle stem cells can cause permanent hair loss, but understanding their role could lead to new treatments.
research Follicular Streamers (Stelae) in Scarring and Non-Scarring Alopecia
Hair root sheaths are more common in non-scarring hair loss and help diagnose the type of hair loss.
research Frontal Fibrosing Alopecia: A Case Series of 65 Patients Seen in a Single Italian Centre
The study concluded that severity of Frontal fibrosing alopecia is not linked to how long someone has it, can start before menopause, and eyebrow loss may be an early sign.
research Alopecia Areata Incognita: True or False?
The authors suggest that a new type of hair loss exists, which is different from alopecia areata.
research Frontal Fibrosing Alopecia: Update and Review of Challenges and Successes
No treatment has been proven to effectively stop hair loss or regrow hair in Frontal Fibrosing Alopecia, and more research is needed.
research Lichen Planopilaris in the Androgenetic Alopecia Area: A Pitfall for Hair Transplantation
Misdiagnosis of LPP in AGA patients can cause hair transplant issues.