Psoriatic Scarring Alopecia: A Case Report

    December 2013 in “ Anais Brasileiros De Dermatologia
    Maiana Carneiro Almeida, Ricardo Romiti, Isabella Doche, Neusa Yuriko Sakai Valente, Aline Donati
    Image of study
    TLDR A woman with long-term scalp psoriasis developed rare scarring hair loss that didn't fully respond to treatments.
    In the case report from 2013, a 42-year-old Caucasian woman with a 22-year history of severe scalp psoriasis developed scarring alopecia after experiencing increased hair shedding associated with episodes of greater inflammation and pruritus. Despite various treatments, including topical clobetasol, oral cyclosporine, methotrexate, UVB-NB phototherapy, and antibiotics, only temporary relief was achieved. Physical examination and dermoscopy revealed erythema, infiltration, scales, crusts, and a lack of follicular openings, with the right parietal side being the most severely affected. Biopsy analysis showed follicular drop-out, absence of sebaceous glands, and fibrosis, with no signs of androgenic alopecia. The findings were consistent with scarring alopecia associated with psoriatic epidermal changes. The report highlights that while hair loss in scalp psoriasis is common, scarring alopecia is a rare complication, and controlling psoriasis inflammation is crucial to prevent progression to scarring alopecia.
    Discuss this study in the Community →

    Research cited in this study

    1 / 1 results

    Related Community Posts Join

    6 / 402 results

      community I am a dermatologist with a clinical interest in alopecia. AMA

      in Will treatment work for me? 2 years ago
      In this conversation, 4990 discussed various treatments for hair loss, including oral minoxidil, PRP, transplan, Jak inhibitors, Dutasteride, Finasteride, Olumiant, Ketoconazole, RU58841, microneedling, baricitinib, and CCCA. They recommended scalp biopsies in unclear cases of DUPA, twice weekly to twice daily shampooing for topical minoxidil users, and two sessions spaced one month apart with follow up at month three to determine the effectiveness of PRP treatment.

      community HT / Meds results are reverting, thinning, crazy shedding..

      in Progress Pictures  161 upvotes 1 month ago
      A user experienced significant hair shedding and thinning 10 months post-hair transplant despite using minoxidil and topical finasteride. They are considering switching to oral finasteride or dutasteride and are also dealing with scalp conditions like seborrheic dermatitis.
      Diffuse hair loss and scalp biopsies

      community Diffuse hair loss and scalp biopsies

      in Research  692 upvotes 3 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

    Related Research

    4 / 4 results