12 citations
,
March 2018 in “Anais brasileiros de dermatologia/Anais Brasileiros de Dermatologia” This article describes a case of frontal fibrosing alopecia in a patient with chronic lichenoid lupus erythematosus and notes the lack of similar documented cases in existing literature.
1 citations
,
January 2021 in “Arthritis Research & Therapy” The study reported a 7.80% prevalence of scarring alopecia in Chinese SLE patients and identified several risk factors, including mucocutaneous lesions and high disease activity, while renal and cardio-respiratory involvements were negatively associated with it.
1 citations
,
January 2018 in “ARC Journal of Dermatology” A patient had both chronic lupus and systemic scleroderma, requiring careful treatment to manage symptoms.
17 citations
,
July 2019 in “Lupus Science & Medicine” In this study, gene expression analysis of plucked hair follicles from scalp lesions was sufficient to differentiate chronic discoid lupus erythematosus from psoriasis and healthy controls, suggesting a non-invasive diagnostic potential.
8 citations
,
August 2019 in “JAAD case reports” This narrative review discusses the presentation and progression of discoid lupus erythematosus in chronic cutaneous lupus erythematosus and does not report new research findings.
May 2025 in “The Journal of Rheumatology” This report describes two cases where female patients with chronic granulomatous disease developed manifestations of systemic lupus erythematosus, highlighting a rare association that may influence clinical evaluation and treatment planning.
In this multicenter study, belimumab effectively reduced disease activity in systemic lupus erythematosus patients with joint and skin manifestations, showing significant improvement in acute and subacute skin types earlier than in chronic types, while no significant benefit was observed for nonspecific skin manifestations.
November 2020 in “Research Square (Research Square)” This study found that 7.80% of Chinese patients with systemic lupus erythematosus experienced scarring alopecia, with certain disease characteristics and treatments influencing its prevalence.
August 2020 in “Research Square (Research Square)” This study reported that 7.80% of systemic lupus erythematosus patients experienced scarring alopecia, with mucocutaneous lesions and certain autoantibodies identified as risk factors, and some organ involvements and immunosuppressants as protective factors.
16 citations
,
August 2017 in “Lupus” This case report and literature review highlights an unusual acne-like presentation of chronic cutaneous lupus erythematosus that doesn't improve with standard acne treatments, emphasizing the importance of considering CCLE in atypical acneiform eruptions.
12 citations
,
March 2004 in “International Journal of Dermatology” A woman with X-linked chronic granulomatous disease developed lupus-like skin lesions, improved with treatment, suggesting a unique skin condition in carriers.
1 citations
,
August 2020 in “International Journal of Dermatology” This article discusses the reversibility of alopecia caused by chronic cutaneous lupus erythematosus but reports no new clinical results.
1 citations
,
June 2014 in “Serbian Journal of Dermatology and Venereology” This case report describes a 22-year-old woman initially suspected of alopecia areata, whose scalp lesions were ultimately diagnosed as discoid lupus erythematosus after histopathological analysis.
December 2022 in “Research Square (Research Square)” In this study, type I interferon response-related genes activated by RIG-1 and IL-17 signaling pathways were significantly up-regulated in both hair follicles and skin tissues affected by chronic discoidal lupus erythematosus.
October 2022 in “Research Square (Research Square)” This study found that type I interferon response-related genes activated by RIG-1 and IL-17 pathways were significantly up-regulated in hair follicle and skin samples with chronic discoidal lupus erythematosus.
11 citations
,
August 1948 in “Journal of Investigative Dermatology” In this study, oral calcium pantothenate was associated with improvement in the inflammatory phase of discoid lupus erythematosus of the scalp, with the most marked response observed in subacute cases.
8 citations
,
September 2013 in “Journal of Social Service Research” This study found that frequent lupus flare-ups, hair loss, hospitalization, and fatigue significantly impacted depression, anxiety, and socioeconomic coping, while having supportive friends reduced these emotional challenges.
November 2021 in “European Heart Journal Supplements” In this case report, a 29-year-old woman with systemic lupus erythematosus and an increased risk of thrombosis experienced improved right heart function following diuretics, anticoagulants, corticosteroids, and immunosuppressants treatment.
November 2021 in “European Heart Journal Supplements” This case report describes a woman with systemic lupus erythematosus who developed chronic thromboembolic pulmonary hypertension, leading to improved right heart function after treatment with diuretics, anticoagulants, corticosteroids, and immunosuppressants.
7 citations
,
November 2007 in “Annales de Dermatologie et de Vénéréologie” A man was diagnosed with a rare form of lupus after showing unique skin symptoms that responded well to treatment.
August 2019 in “Blucher Medical Proceedings” This article reviews the characteristics of Lupus Erythematosus Panniculitis as a rare variant of Chronic Cutaneous Lupus Erythematosus, with no new clinical results reported.
157 citations
,
August 2010 in “Lupus” This review discusses the various common, rare, and unusual skin manifestations of lupus erythematosus and highlights the importance of accurate diagnosis, but it reports no new clinical results.
149 citations
,
July 2002 in “Dermatologic clinics” This review discusses the pathogenesis, clinical presentation, diagnosis, and treatment of cutaneous lupus erythematosus, reporting no new clinical findings.
148 citations
,
February 2005 in “Autoimmunity Reviews” This article discusses the distinct skin findings associated with lupus erythematosus, noting that some are specific to lupus while others are nonspecific and occur with various diseases; it reports no new results.
132 citations
,
July 2000 in “Lupus” This study found that chronic cutaneous lupus erythematosus with discoid lesions was the most common skin manifestation among patients with lupus erythematosus, while nonspecific skin lesions were linked to systemic lupus erythematosus, particularly during active disease phases.
74 citations
,
March 2001 in “Seminars in Cutaneous Medicine and Surgery” This review summarizes the cutaneous manifestations of lupus erythematosus, noting both non-specific and disease-specific lesions, and highlights the role of skin biopsies and treatments available for cutaneous LE.
31 citations
,
January 2009 in “Autoimmunity Reviews” This study suggests that damage to stem cells in the bulge region of hair follicles may contribute to scarring in chronic cutaneous lupus erythematosus.
19 citations
,
September 2010 in “Journal of the European Academy of Dermatology and Venereology” This study found that while the CLASI is generally useful for assessing disease activity and damage in cutaneous lupus erythematosus, it may not accurately reflect all subtypes, indicating a need for revision.
3 citations
,
March 2021 in “Clinical, Cosmetic and Investigational Dermatology” This study reviews the types of alopecia associated with lupus erythematosus and discusses treatment challenges, highlighting that non-scarring alopecia is specific to systemic lupus while chronic cutaneous lupus can cause scarring alopecia, with topical corticosteroids and oral antimalarials as primary treatments for cutaneous lupus erythematosus.
2 citations
,
January 2004 in “Elsevier eBooks” This article reviews historical uses of the term "lupus" for various skin disorders but provides no new clinical findings.