Plucked Hair Follicles From Patients With Chronic Discoid Lupus Erythematosus Show a Disease-Specific Molecular Signature

    July 2019 in “ Lupus Science & Medicine ”
    Mohammad Shalbaf, Adewonuola Alase, Anna Berekméri … Miriam Wittmann
    Studysummary In this study, gene expression analysis of plucked hair follicles from scalp lesions was sufficient to differentiate chronic discoid lupus erythematosus from psoriasis and healthy controls, suggesting a non-invasive diagnostic potential.
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    Research cited in this study 6

    1. Regeneration of Fat Cells from Myofibroblasts During Wound Healing Science · 2017
    2. Primary Cicatricial Alopecia: Treatment Approaches and Classification Journal of The American Academy of Dermatology · 2016
    3. Lichen Planopilaris Is Characterized By Immune Privilege Collapse Of The Hair Follicle's Epithelial Stem Cell Niche The Journal of Pathology · 2013
    4. Scar Classification in Cutaneous Lupus Erythematosus: Morphological Description British Journal of Dermatology · 2009
    5. Human Follicular Stem Cells: Their Presence in Plucked Hair and Follicular Cell Culture British Journal of Dermatology · 2004
    6. Bone Morphogenetic Proteins and Their Antagonists in Skin and Hair Follicle Biology Journal of Investigative Dermatology · 2003

    Related research 1

    1. Hair and Scalp Changes in Cutaneous and Systemic Lupus Erythematosus American Journal of Clinical Dermatology · 2018