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C-scores can help predict gain-of-function and loss-of-function mutations.

Spironolactone works well for acne and hirsutism, isotretinoin is very effective for acne and may have antiandrogenic effects, and 5 alpha-reductase inhibitors should be considered antiandrogens.

Maintaining DNA integrity in stem cells is crucial to prevent aging and cancer.

Toxic shock syndrome is caused by a complex interaction of bacterial toxins and the immune system, and understanding this can help improve diagnosis and treatment.

A mutation in the HR gene causes a rare form of irreversible hair loss in two Kashmiri families. Whole exome sequencing is effective for finding such mutations.

Scientists successfully made a human growth factor in a plant, which could help with hair growth and bone development.

5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.

Wnt7a protein is crucial for development and tissue maintenance and plays varying roles in diseases and potential treatments.

A genetic variant in the androgen receptor gene increases heart disease risk in women but not in men.

Early diagnosis and tailored treatments are crucial for managing ichthyosis syndromes with hair abnormalities.

Androgen receptors are active in many tissues of both male and female mice, not just reproductive organs.

Patients with certain skin symptoms and high ANA titers should be monitored for potential systemic lupus.

VDR regulation varies by tissue and is crucial for its biological functions.

Some Greek melanoma patients have gene mutations linked to increased cancer risk, a new color feature helps diagnose melanoma, the incidence of a skin condition in the Netherlands is rare, and a gene possibly affects male-pattern baldness.

Leptin-deficient mice, used as a model for Type 2 Diabetes, have delayed wound healing due to impaired contraction and other dysfunctional cellular responses.

Certain genetic variations in the FST gene are linked to better wool quality in Chinese Merino sheep.

Epigenetic mechanisms control skin development by regulating gene expression.

A baby girl has a hair disorder called monilethrix, causing fragile hair that may improve over time.

A new method helps detect androgen receptor movement in cells, aiding research on hair loss treatments.

The enzymes Tet2 and Tet3 are important for skin cell development and hair growth.

Cri-du-chat syndrome can cause skin and oral lesions affecting nutrition and quality of life.

Early detection of specific skin lesions can help identify Birt-Hogg-Dube syndrome and prevent serious complications.

Cholesterol sulfate buildup due to a genetic mutation disrupts the skin barrier, leading to the scaling skin seen in X-linked ichthyosis.

WNT10B is linked to cancer development and affects survival and disease progression in various cancers.

Feather patterns are influenced by enhancers and chromatin looping, and the structure of protein complexes important for hair growth has been detailed.

Different versions of the KRTAP6-2 gene in goats can lead to thinner cashmere fibers.

Sex neurosteroids cause different effects on hippocampal synaptic plasticity in males and females.

Prolactin levels and gene polymorphism are not linked to vitiligo severity but are related to BMI.

MED1 is essential for normal hair growth and maintaining hair follicle stem cells.

A new mutation in the TRPS1 gene was found in a Ukrainian girl with Trichorhinophalangeal syndrome type I.