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Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

Damage to skin releases dsRNA, which activates TLR3 and helps in skin and hair follicle regeneration.

Cepharanthine is a well-tolerated drug with multiple medical uses, including anti-inflammatory and anti-cancer properties.

MicroRNA-302 helps improve the conversion of body cells into stem cells by blocking NR2F2.

Estrogens help reduce skin aging, and SERMs might offer similar benefits without the risks of hormone therapy.

The document concludes that while significant progress has been made in understanding skin biology and stem cells, more research is needed to fully understand their interactions with their environment.

The AUTS2 gene is linked to neurological disorders and may affect human brain development and cognition.

The article concludes that the wool follicle is a valuable model for studying tissue interactions and has potential for genetic improvements in wool production.

The research found that Atypical Progeroid Syndrome has unique symptoms and is not caused by the buildup of a certain mutant protein.

Men, especially older ones with health issues like prostate cancer, may have worse COVID-19 outcomes and could benefit from therapies targeting male hormones.

We need more research to better understand human hair follicle stem cells for improved treatments for hair loss and skin cancer.

A genetic region near the PAX1 gene is linked to a higher risk of scoliosis in females.

MicroRNA-214 is important for skin and hair growth because it affects the Wnt pathway.

Scientists created stem cells that can grow hair and skin.

Removing both Atr and Trp53 genes in adult mice causes severe tissue damage and death due to DNA damage.

Mutant CDP/Cux protein causes hair defects and reduced male fertility in mice.

Notch/CSL signaling controls hair follicle differentiation through Wnt5a and FoxN1.

The circadian clock is crucial for tissue renewal and regeneration, affecting stem cell functions and having implications for health and disease.

Mice studies show that Protein Phosphatase 2A is crucial for cell growth, development, and disease prevention.

TCDD speeds up skin barrier formation by increasing certain gene expressions.

The article concludes that better understanding gene regulation related to seasonal changes can offer insights into the mechanisms of seasonal timing in mammals.

Keratin 15 is not a reliable sole marker for identifying epidermal stem cells because it's found in various cell types.

Changes to the Foxp3 protein affect how well regulatory T cells can control the immune system, which could help treat immune diseases and cancer.

The TGF-β family helps control how cells change and move, affecting skin, hair, and organ development.

TPA is about 50 times more effective at promoting tumors than MZ.

YAP and TAZ proteins are necessary for the development of two types of skin cancer.

The HR protein's role as a repressor is essential for controlling hair growth.

Exosomes from dermal papilla cells help hair growth by making hair follicle stem cells multiply and change.

Short-chain fatty acids from *Cutibacterium acnes* cause skin inflammation, contributing to acne.

Hormonal treatment in transgender women reduces semen quality, but stopping treatment may improve it.