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The conclusion is that genetic changes in the glucocorticoid receptor can lead to conditions affecting stress response, immunity, and metabolism, requiring personalized treatment.

Mutations in the SRD5A3 gene cause a new type of glycosylation disorder by blocking the production of a molecule necessary for protein glycosylation.

Two specific hair keratin genes are active during hair growth and decline as hair transitions to rest.

New methods to make oxasteroids show promise for medical treatments like osteoporosis and breast cancer.

Future work on macrolide antibiotic analysis will aim to enhance selectivity, sensitivity, and efficiency using advanced chromatographic methods.

SHBG binding properties are unchanged in male liver cirrhosis patients.

Hair follicle stem cells use specific chromatin changes to control their growth and differentiation.

The protein STAT3 slows down cell growth by blocking the FST gene, which affects hair development in sheep.

Different signals work together to change gene activity and guide hair follicle stem cells to become specific cell types.

SOX9 helps determine stem cell roles by interacting with DNA and proteins that control gene activity.

Key genes can rewire networks, changing skin appendage types.

Epigenetic factors play a crucial role in skin health and disease.

KLF4 is important for keeping hair follicle stem cells inactive.

The protein CTCF is essential for skin development, maintaining hair follicles, and preventing inflammation.

BAF200 is essential for proper heart and coronary artery formation.

HOXC13 is essential for hair and nail development by regulating Foxn1.

A new molecule was found to be a safe and effective skin lightener and anti-aging product.

Enhancers and super-enhancers are key in controlling specific gene activity and can play a role in cancer development.

Studying premature aging syndromes helps understand human aging and suggests potential treatments.

Diet changes can protect against harmful environmental effects on fetal development.

An alpaca acted like a male and couldn't have babies because of a benign tumor in its ovary that caused high testosterone levels.

mTORC1 activity is important for hair growth and color, and targeting it could help treat hair loss and greying.

DNMT1 helps turn hair follicle stem cells into fat cells by blocking a specific microRNA.

Colorectal cancer development involves both genetic changes and epigenetic alterations like DNA methylation and microRNA changes.

The tumor suppressor BRCA2 helps in cell division by bringing key proteins to the area where cells split.

A defective protein in progeria causes cell death and atherosclerosis, but a treatment targeting cell stress may reduce these effects.

The balance between androgen receptor and p53 is crucial for sebaceous gland differentiation.

Men with hair loss have more DNA changes in back-of-head hair follicles, possibly protecting them from thinning.

DNA methylation changes are linked to hair growth cycles in goats.

Mutations in the glucocorticoid receptor gene cause reduced sensitivity to glucocorticoids and may lead to poor response to treatment.