2 citations
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October 2023 in “Skin Health and Disease” This case report describes a rare instance of alopecia neoplastica, where breast cancer metastasized to the scalp, which can be mistakenly diagnosed as alopecia areata.
3 citations
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January 2022 in “JAAD Case Reports” This article reports a unique case of a 60-year-old woman with alopecia areata and myasthenia gravis, suggesting a rare paraneoplastic syndrome connection primarily limited to prior reports involving hematologic cancers.
November 1997 in “Open Archive (Karolinska Institutet)” This research observed that mutations in the PTCH gene are common in both sporadic and hereditary basal cell cancers, suggesting a critical role of the PTCH signaling pathway in skin tumor development.
1 citations
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January 2023 in “Journal of Drugs in Dermatology” This review discusses Graham-Little Piccardi-Lasseur syndrome, a rare dermatosis with limited treatment options, emphasizing the importance of early diagnosis through physical exam and dermoscopy, but reports no new results.
3 citations
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March 2023 in “Annals of the New York Academy of Sciences” In this study using mice, simultaneous deficiencies in claudin-1 and claudin-3 were associated with hair loss and altered hair follicle architecture during the telogen phase, suggesting a role in hair retention.
This study found that Chrysanthemum zawadskii extract may promote hair growth by inducing an earlier conversion of telogen to anagen and increasing the proliferation of dermal papilla cells in mice and human hair follicle cultures.
April 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” This case report identified a 6-month-old girl with congenital generalized hypertrichosis and gingival hyperplasia, where a de novo CNV on chromosome 17q24.2-24.3 was associated with reduced expression of ABCA5 and SOX9.
February 2017 in “Cancer Research” In this study involving women undergoing taxane-based chemotherapy, a twice-daily topical application of BPM31543 was well-tolerated and showed potential in reducing severe hair loss, prompting further investigation at higher doses.
September 2022 in “Scientific Reports” This study found that scalp melanoma often occurs in areas with androgenetic alopecia, and patients without alopecia might experience a later diagnosis due to hair coverage, leading to potentially worse outcomes.
4 citations
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November 2021 in “Journal of Clinical Medicine” This study found no significant differences in certain proinflammatory protein levels between patients with alopecia areata and healthy controls but noted a potential association between disease severity and increased atherosclerosis risk.
3 citations
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January 2022 in “Medical Mycology Journal” This study observed Malassezia hyphae in the keratotic plugs of healthy individuals, which contrasts with previous findings of these hyphae primarily in lesions of pityriasis versicolor patients.
December 2023 in “JEADV Clinical Practice” This study found that dermoscopy of the axilla in patients with frontal fibrosing alopecia revealed significantly higher odds of brownish peripillary halos, suggesting a diagnostic clue for the condition in this region.
June 2023 in “Dermatopathology” In this case report, researchers described a unique skin lesion in a 55-year-old woman, identifying it as folliculosebaceous cystic hamartoma with an unusual combination of spindle cell lipomatous and neural components, which had not been previously documented in such cases.
July 2025 in “International Journal of Molecular Sciences” This study found that blocking the chemokine CXCL12 in a testosterone-induced mouse model of androgenetic alopecia restored hair regeneration and reduced fibrosis and immune alterations.
29 citations
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February 1989 in “Journal of Cutaneous Pathology” This case report identifies a new type of hair matrix tumor called "rippled pattern trichomatricoma," distinguished by its unique cell arrangement and differentiation features.
27 citations
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March 2008 in “Journal of The European Academy of Dermatology and Venereology” Men with a certain type of hair loss (AGA) have higher bad cholesterol and lower good cholesterol levels, making them more likely to get heart disease.
January 2024 in “International Journal of Molecular Sciences” This study found that subcutaneous injection of a CXCL12 neutralizing antibody significantly promoted hair growth in androgenic alopecia and inhibited hair loss in alopecia areata in mouse models, suggesting its potential as a promising treatment for hair loss.
October 2024 in “Medicine” In this case report, a 72-year-old female with Cronkhite-Canada syndrome showed significant improvement in symptoms and gastrointestinal polyps after hormone therapy and additional treatment.
This study undertook a retrospective chart review to examine the link between the severity of female pattern hair loss and abnormal cholesterol levels in patients from a specialty alopecia clinic, but results are not reported.
January 2024 in “Revista Dermatológica Centro Uraga” This case report describes a 68-year-old woman diagnosed with chronic cutaneous lupus, characterized by irregular plaques with distinct pigmentation and scarring alopecia, confirmed through histopathology revealing specific skin changes.
April 2019 in “Journal of Investigative Dermatology” This study found that frontal fibrosing alopecia involves distinct molecular changes, such as downregulation of steroid and cholesterol pathways and upregulation of fibrotic and immune response genes, which may help guide treatment strategies.
10 citations
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March 1997 in “Pediatric Dermatology” This case report describes a patient with trichothiodystrophy presenting with autism, mental retardation, and seizures, characterized by distinct hair abnormalities under microscopy.
This study identified a genetic locus associated with rhabdomyosarcoma susceptibility in mice and found that specific differentiation markers are linked to the regression of basal cell carcinoma.
29 citations
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July 2008 in “British Journal of Dermatology” This case report examines a patient with myasthenia gravis, invasive thymoma, and paraneoplastic pemphigus associated with alopecia areata, notably without the usual mucosal involvement.
6 citations
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September 2024 in “Plant Cell & Environment” This study found that in Arabidopsis root hairs, mild chitosan treatment triggered callose deposition and slowed growth, while a higher concentration inhibited growth without callose deposition, indicating different responses based on chitosan concentration.
January 2023 in “Annals of Dermatology” This study found that alopecia areata patients with a CCHCR1 gene variant had higher recurrence rates and structural abnormalities in hair compared to those without the variant.
21 citations
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October 1980 in “Gastroenterology” This report is the first to associate Cronkhite-Canada syndrome with multiple myeloma, describing regenerative pseudopolyps in a 58-year-old woman rather than true adenomatous polyps.
64 citations
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May 1981 in “Clinical and Experimental Dermatology” This case report describes a patient with myasthenia gravis, alopecia, and hair follicle hamartoma, showing notable similarities to a previously reported case.
2 citations
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March 2019 in “Veterinary dermatology” The authors concluded that thymoma-associated paraneoplastic syndrome in cats may manifest as noninflammatory alopecia instead of exfoliative dermatitis, and should be considered when diagnosing multifocal noninflammatory alopecia.
December 2021 in “Pathologica” This case report describes a rare instance of trichogerminoma with unusually numerous mitotic figures and a higher Ki67 proliferative rate, distinguishing it from previously documented cases.