Clinical Findings, Response to Steroid Treatment, and Recurrence Rate in Alopecia Areata Patients With or Without a Nonsynonymous Variant of Coiled-Coil Alpha-Helical Rod Protein 1

    January 2023 in “ Annals of Dermatology ”
    Satoshi Koyama, Nagisa Yoshihara, Atsushi Takagi … Shigaku Ikeda
    Studysummary This study found that alopecia areata patients with a CCHCR1 gene variant had higher recurrence rates and structural abnormalities in hair compared to those without the variant.
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    Research cited in this study 10

    1. Alopecia Areata Susceptibility Variant in MHC Region Impacts Expressions of Genes Contributing to Hair Keratinization and Is Involved in Hair Loss EBioMedicine · 2020
    2. Factors Associated With Severity Of Alopecia Areata Annals of Dermatology · 2017
    3. Familial Aggregation of Alopecia Areata Journal of the American Academy of Dermatology · 2016
    4. Alopecia Areata and Health-Related Quality of Life: A Systematic Review and Meta-Analysis British Journal of Dermatology · 2016
    5. Biomarkers of Alopecia Areata Disease Activity and Response to Corticosteroid Treatment Experimental dermatology · 2015
    6. Genome-Wide Association Study in Alopecia Areata Implicates Both Innate and Adaptive Immunity Nature · 2010
    7. Alopecia Areata Update Journal of The American Academy of Dermatology · 2010
    8. Lymphocytes, Neuropeptides, And Genes Involved In Alopecia Areata Journal of Clinical Investigation · 2007
    9. Alopecia Areata: Overview and Treatment Options International Journal of Dermatology · 2007
    10. Juvenile Versus Maturity-Onset Alopecia Areata: A Comparative Retrospective Clinical Study Clinical and Experimental Dermatology · 1989

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