November 2017 in “Journal of cosmetology & trichology” The combined treatment of a specific hair cocktail and microneedling device effectively restores hair in different baldness patterns.
July 2025 in “Cosmoderma” In this study, a 90-day course of a plant-based supplement significantly improved hair density, skin hydration, and nail growth among participants with dermatological concerns, while also reducing hair fall and pigmentation, without adverse effects.
December 2022 in “Cosmetics” This study found that a novel nutraceutical supplement improved hair growth and strength in subjects with hair thinning compared to placebo, without reported side effects.
December 2025 in “Plastic & Reconstructive Surgery” This study found that the Bioengineered Exosomal Hair Growth Factors Complex (BEHC™) enhanced human follicle dermal papilla cell proliferation and reduced inflammatory markers in vitro, while significantly decreasing hair shedding and increasing hair density among participants with androgenetic alopecia in an open-label clinical study.
July 2025 in “JAAD Case Reports” September 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This research introduces the MHS Hair Restoration Protocol, which is a comprehensive approach aimed at restoring the hair follicle environment by modulating the gut-microbiome-endocannabinoidome axis and incorporating specific dietary and topical strategies, rather than focusing only on short-term hair count improvements.
This study developed a natural hair dye using Coreopsis tinctoria Nutt. extract, finding that it produced yellow to dark brown colors depending on the treatment, with ferrous lactate enhancing dye performance and color stability after washing.
November 2024 in “Journal of Clinical Medicine” This study observed that six sessions of injections using a stabilized hyaluronic acid compound improved hair thickness, shine, density, and reduced hair loss in volunteers with moderate androgenetic alopecia, with excellent treatment tolerability and high satisfaction reported by 88.5% of participants.
7 citations
,
May 2021 in “Dermatologic Clinics” Nutraceuticals like Ashwagandha and Astaxanthin may help with hair loss, but supplement regulation is challenging.
February 2024 in “Cosmetics” The correction fixes an image mistake in the original publication, but the findings on the hair treatment's effectiveness are unchanged.
2 citations
,
November 2019 in “Journal of Medicinal Food”
May 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This review examines the use of horsetail extract in cosmetics, highlighting its antioxidant, anti-aging, and skin-enhancing properties due to its rich phytochemical content, but notes that standardization and clinical validation remain challenges.
May 2025 in “International Journal of Trichology” In this study, Pilopeptan® Intensive, a nutritional supplement containing hydrolyzed collagen, Group B vitamins, and zinc, was found to significantly improve hair parameters in telogen effluvium patients, with sustained benefits observed posttreatment, although mild side effects were reported by some participants.
17 citations
,
September 2024 in “Cosmetics” This study assessed the antioxidant properties and contents of carotenoids and chlorophylls in 10 plant oils, finding fenugreek seed oil to be highest in carotenoids and pomegranate oil most active against free radicals, highlighting their potential as natural materials with antioxidant benefits.
This study found that a food supplement containing L-cystine, pantothenic acid, biotin, and millet extract significantly improved hair density and beauty parameters in healthy Japanese women with light diffuse hair loss after three months.
January 2013 in “Journal of Siberian Medical Sciences” This study found that patients with androgenetic alopecia experienced higher treatment efficacy when using a combination of antler-based products "Pantogematogen" and "Chudopan" compared to other methods.
7 citations
,
August 2021 in “Heliyon” This study suggests that the herbal formulation Phyllotex™ may promote hair growth in androgenetic alopecia by enhancing cell proliferation and reducing oxidative stress and TGF-β1 expression in vitro.
July 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This review reports that herbal cosmetics offer diverse biological benefits, including antioxidant, antibacterial, and moisturizing effects, enhanced by advanced formulation methods, while emphasizing the need for more clinical validation and standardized practices to ensure long-term safety and efficacy.
May 2026 in “Materials Today Bio” This study reported that a bioderived melanoidin/tannic acid nanocomplex forms a durable, antioxidant-active coating on hair fibers, providing enhanced UV protection and improving tensile resilience by suppressing oxidative stress and activating endogenous antioxidant pathways.
26 citations
,
January 2016 in “Annals of Dermatology” This study found that Ecklonia cava polyphenols increased human dermal papilla cell proliferation and extended hair shaft length in vitro and ex vivo, suggesting potential as a therapeutic candidate for hair loss.
June 2023 in “Italian journal of dermatology and venereology” In this study, researchers evaluated an oral supplement containing arginine, l-cystine, zinc, and vitamin B6, finding it effective as an adjuvant treatment for telogen effluvium, as indicated by improved hair quantity and diameter after three months in 18 patients.
1 citations
,
November 2023 in “Acta Dermato Venereologica”
April 2017 in “Journal of dermatology & cosmetology” In this controlled study, a 6-month treatment with the nutraceutical product ViviScal® reduced telogen hair fibers and increased total hair fibers in 83% of participants with Telogen Effluvium, who also reported improved hair and nail growth, skin appearance, and overall quality of life.
September 2025 in “PubMed” In this study, the combined use of Exosome Regenerative Complex and RF microneedling significantly improved hair density, hair growth, and hair quality in subjects with self-perceived thinning hair, showing high satisfaction with no adverse events after 120 days of treatment.
January 2019 in “Research Square (Research Square)” In this study, researchers will conduct a randomized, double-blind, multi-center clinical trial to assess the effectiveness of YH0618 granule in preventing chemotherapy-induced hair loss among breast cancer patients, aiming to understand its mechanism related to kidney deficiency in Chinese Medicine. Results are not yet reported.
September 2022 in “Ukraïnsʹkij naukovo-medičnij molodìžnij žurnal” This study found that providing quality pharmaceutical care is crucial for safe and effective use of vitamin and mineral supplements during pregnancy and breastfeeding, as many women incorrectly perceive them as entirely safe.
1 citations
,
July 2012 in “EFSA Journal” The Panel concluded that there is no established cause and effect relationship between the specified vitamin and pumpkin seed oil combination and the maintenance of normal hair in healthy adults.
January 2016 in “Huanjing yu Jiankang Zazhi”
February 2022 in “Research Square (Research Square)” In this cell-based study, researchers found that certain nutraceuticals combined with tamoxifen may influence estrogen receptor expression, potentially offering a protective effect and promoting hair growth during breast cancer therapy.
May 2026 in “Zenodo (CERN European Organization for Nuclear Research)” In this review, the authors provide a comprehensive overview of Equisetum arvense (horsetail) as a promising natural ingredient in cosmetics, highlighting its antioxidant, anti-aging, anti-inflammatory, and wound-healing properties, while also noting challenges related to standardization and clinical validation.