Clinical Study on the Efficacy and Tolerability of an Oral Supplement Based on Arginine, L-Cystine, Zinc and B6 Vitamin (Cystiphane) in Patients With Telogen Effluvium

    Michela STARACE, Stephano Cedirian, Francesca BRUNI … Bianca Maria Piraccini
    Studysummary In this study, researchers evaluated an oral supplement containing arginine, l-cystine, zinc, and vitamin B6, finding it effective as an adjuvant treatment for telogen effluvium, as indicated by improved hair quantity and diameter after three months in 18 patients.
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    Research cited in this study 33

    1. Hair Loss and Telogen Effluvium Related to COVID-19: The Potential Implication of Adipose-Derived Mesenchymal Stem Cells and Platelet-Rich Plasma as Regenerative Strategies International Journal of Molecular Sciences · 2022
    2. Targeted Nutritional Supplementation for Telogen Effluvium: Multicenter Study on Efficacy of a Hydrolyzed Collagen, Vitamin, and Mineral-Based Induction and Maintenance Treatment International Journal of Trichology · 2022
    3. A New Combination of Molecules for the Treatment of Androgenetic Alopecia and Telogen Effluvium: A Double-Blind Randomized, Monocentric, Placebo-Controlled Study Italian journal of dermatology and venereology · 2022
    4. Update on Trichoscopy: Integration of Terminology by Systematic Approach and Proposal of a Diagnostic Flowchart The Journal of Dermatology · 2021
    5. An Anti-Hair Loss Treatment in the Management of Mild Androgenetic Alopecia: Results from a Large, International Observational Study Dermatologic Therapy · 2021
    6. Trichodynia and Telogen Effluvium in COVID-19 Patients: Results of an International Expert Opinion Survey on Diagnosis and Management JAAD International · 2021
    7. The Effectiveness and Tolerability of Preformed Growth Factors Delivered Through Iontophoresis on Patients with Androgenetic Alopecia and Telogen Effluvium: A Clinical Study Dermatology practical & conceptual · 2021
    8. Hair Loss After Metabolic and Bariatric Surgery: A Systematic Review and Meta-Analysis Obesity surgery · 2021
    9. Common Causes of Hair Loss: Clinical Manifestations, Trichoscopy, and Therapy Journal of the European Academy of Dermatology and Venereology · 2020
    10. Telogen Effluvium: A Review of the Literature Cureus · 2020
    11. Telogen Effluvium: A Comprehensive Review Clinical, Cosmetic and Investigational Dermatology · 2019
    12. Preliminary Results of the Use of Scalp Microneedling in Different Types of Alopecia Journal of Cosmetic Dermatology · 2019
    13. The Role of Vitamins and Minerals in Hair Loss: A Review Dermatology and Therapy · 2018
    14. Hair Loss After Laparoscopic Sleeve Gastrectomy Obesity surgery · 2018
    15. Physiological Changes of Pregnancy: A Review of the Literature International Journal of Women's Dermatology · 2017
    16. The Role of Micronutrients in Alopecia Areata: A Review American Journal of Clinical Dermatology · 2017
    17. Prevalence of Nutritional Deficiencies in Hair Loss Among Indian Participants: Results of a Cross-Sectional Study International Journal of Trichology · 2017
    18. Proposing a Simpler Classification of Telogen Effluvium Skin appendage disorders · 2016
    19. Nutrition of Women with Hair Loss During Menopause Przeglad Menopauzalny · 2016
    20. Non-Invasive Method Distinguishes Chronic Telogen Effluvium From Mild Female Pattern Hair Loss: Clinicopathological Correlation International Journal of Dermatology · 2015
    21. Telogen Effluvium: A Review of Acute and Chronic Forms Indian Journal of Dermatology, Venereology and Leprology · 2013
    22. Chemoprevention of Doxorubicin-Induced Alopecia in Mice by Dietary Administration of L-Cystine and Vitamin B6 Archives of Dermatological Research · 2012
    23. A Novel Cosmetic Approach to Treat Thinning Hair British Journal of Dermatology · 2011
    24. The Role of Scalp Dermoscopy in the Diagnosis of Alopecia Areata Incognita Journal of The American Academy of Dermatology · 2008
    25. Hair Loss in Children in South-East Nigeria: Common and Uncommon Cases International Journal of Dermatology · 2007
    26. Diffuse Alopecia in a Child Due to Dietary Zinc Deficiency SKINmed Dermatology for the Clinician · 2007
    27. Chemoprevention of Smoke-Induced Alopecia in Mice by Oral Administration of L-Cystine and Vitamin B6 Journal of dermatological science · 2007
    28. Approach to the Adult Female Patient with Diffuse Nonscarring Alopecia Journal of The American Academy of Dermatology · 2002
    29. Nutritional Factors and Hair Loss Clinical and Experimental Dermatology · 2002
    30. Indications for a Brain-Hair Follicle Axis: Inhibition of Keratinocyte Proliferation and Up-Regulation of Keratinocyte Apoptosis in Telogen Hair Follicles by Stress and Substance P The FASEB Journal · 2001
    31. The Psychology of Hair Loss and Its Implications for Patient Care Clinics in Dermatology · 2001
    32. Chronic Telogen Effluvium: Increased Scalp Hair Shedding in Middle-Aged Women Journal of The American Academy of Dermatology · 1996
    33. Telogen Effluvium: A Comprehensive Review Archives of Dermatology · 1993

    Related research 5

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    2. The Effectiveness and Tolerability of Preformed Growth Factors Delivered Through Iontophoresis on Patients with Androgenetic Alopecia and Telogen Effluvium: A Clinical Study Dermatology practical & conceptual · 2021
    3. A Clinico-Epidemiological Study of Scalp Hair Loss in Children (0–18 Years) in Kota Region, South-East Rajasthan Indian Journal of Dermatology · 2019
    4. Nourkrin: Objective and Subjective Effects and Tolerability in Persons with Hair Loss Journal of International Medical Research · 2006
    5. Efficacy and Tolerability of Finasteride 1 mg in Men Aged 41 to 60 Years with Male Pattern Hair Loss PubMed · 2003