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Hair follicle stem cells use specific chromatin changes to control their growth and differentiation.

The document concludes that developing generic topical drugs requires ensuring they match the original in quality, composition, and structure, and often involves complex testing and regulatory steps.

The 2003 guidelines suggest that while some treatments can regrow hair in alopecia areata, none alter the disease's progression, and wigs may be the best option for extensive hair loss.

Testosterone therapy in transgender men has both desired effects like increased muscle mass and potential health risks such as higher cardiovascular risk.

Women with PCOS have a higher risk of diabetes and heart problems, especially when they get older.

The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.

Pig skin is a good substitute for human skin to measure drug absorption, but differences in skin structure and enzymes across species must be considered.

The document concludes that accurate diagnosis of ichthyosis is crucial for treatment and genetic advice, and ongoing research is needed for better therapies.

Microneedles improve drug delivery in various body parts, are safe and painless, and show promise in cosmetology, vaccination, insulin delivery, and other medical applications.

Vitamin D is important for skin health and may affect conditions like psoriasis and hair loss, but more research is needed to understand its role fully.

Eating less sugar, milk, and saturated fats and more vegetables and fish may help treat and prevent acne.

Masculine facial features may not reliably indicate heritable health, and more research is needed.

Exosomes could potentially enhance tissue repair and regeneration with lower rejection risk and easier production than live cell therapies.

Early detection and intensive treatment of diseases caused by Staphylococcus aureus toxins are crucial for reducing severe health effects.

Surgeons must understand the full care process for gender confirmation surgery to help transgender individuals effectively.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

The conclusion is that the increasing use of drugs for lifestyle reasons is a complex issue influenced by corporate profit, consumer behavior, and the medicalization of everyday life, with potential negative effects on personal well-being.

Liposomes could improve how skin care products work but are costly and not very stable.

South Asian women with PCOS are more likely to have metabolic issues and central obesity, and simple measures like waist size and blood pressure can help identify these risks early.

Testosterone treatment in trans men increases body and facial hair and may lead to hair loss over time, but severe skin issues are rare.

The document concludes that hair is complex, with a detailed growth cycle, structure, and clinical importance, affecting various scientific and medical fields.

A mother's PPARγ is crucial for preventing harmful milk that can cause inflammation and growth problems in babies.

Very few people experience increased hair growth after laser hair removal, especially those with darker skin and black hair.

Different soft tissue fillers can cause various skin reactions; biodegradable fillers are safer and non-biodegradable ones like silicone can lead to long-term problems.

Hair elemental analysis could be useful for health and exposure assessment but requires more standardization and research.

Sensitive skin is often caused by nerve fibers and environmental factors, and can be managed with mild skincare and professional advice.

Researchers identified genes linked to coat color, body size, cashmere production, and high altitude adaptation in goats.

Human beard hair medulla contains a unique and complex mix of keratins not found in other human tissues.

Older adults have a high rate of skin cancers like basal cell carcinoma and melanoma, mainly due to UV exposure and age.

Antioxidants can benefit skin health but should be used carefully to avoid negative effects.