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570-600 / 1000+ resultsresearch Drug delivery to the hair follicle : role of follicular tight junctions as a biological barrier and the potential for targeting clobetasol nanocarriers
This study confirmed the porcine ear skin model's effectiveness for studying nanoparticle-based drug delivery in human hair follicles, noting particle-dependent uptake and enhancement by massage.
research All Subcomponents of the Cutaneous Lupus Erythematosus Disease Area and Severity Index–Activity (CLASI-A) are Relevant to Identify and Detect Changes in Skin Activity
This study demonstrated that litifilimab significantly reduced disease activity in cutaneous lupus erythematosus by Week 16, with improvements most notable in sunlight-exposed skin areas.
research High-confidence cancer patient stratification through multiomics investigation of DNA repair disorders
In this study, the researchers identified CEP135 as a biomarker linked to poor sarcoma survival and suggested PLK1 as a potential therapeutic target for sarcoma patients with high CEP135 expression.
research THE FREQUENCY OF VISCERAL AND PHENOTYPIC MARKERS IN PATIENTS WITH THE COMBINATION OF UNDIFFERENTIATED CONNECTIVE TISSUE DISEASE AND GASTROESOPHAGEAL REFLUX DISEASE
This study found that patients with GERD and UCTD have significantly more frequent phenotypic and visceral markers than those with GERD alone, which should inform early diagnostic and treatment strategies.
research The efficacy and safety of tofacitinib in patients with alopecia totalis
Tofacitinib is a potential alternative treatment for alopecia totalis, especially in patients with a shorter duration of the condition and more preserved hair follicles, but the overall response rate is low.
research Real-world assessment of ritlecitinib in patients with severe alopecia areata: a 24-week multicentre retrospective study
This study reported that patients with alopecia areata treated with ritlecitinib in a real-life setting had a higher rate of positive response on the Severity of Alopecia Tool score compared to those in the ALLEGRO trial.
research Evaluation of Serum Zinc Level in Patients with Chronic Telogen Effluvium in Premenopausal Adult Females in Kirkuk City
The researchers reported that adult menstruating females with chronic telogen effluvium had significantly lower serum zinc levels compared to healthy controls, suggesting an association between decreased zinc levels and CTE.
research Identification of drug-specific public TCR driving severe cutaneous adverse reactions
In this study, researchers identified a specific T cell receptor associated with carbamazepine-induced severe cutaneous adverse reactions, demonstrating its potential for therapeutic development in patients with the HLA-B*15:02 genotype.
research Enriched and Enhanced Virgin Coconut Oil (2EVCO) / Saphia Elina May May ... [et al.]
In this study, the application of Enriched and Enhanced Virgin Coconut Oil reportedly improved hair growth and reduced the appearance of scars in a teacher with cancer, suggesting benefits over typical post-chemotherapy recovery.
research 852 Targeted deletion of crif1 in mouse skin epidermis impairs skin homeostasis
Deleting Crif1 in mouse skin disrupts skin balance and hair growth.
research 169 TEDAR, a skin-specific long non-coding RNA, orchestrates the late epidermal differentiation program in the human epidermis
TEDAR is crucial for skin cell differentiation and barrier formation.
research Clinical and Cure Profile of Tinea Capitis Patients
This study reviewed medical records of tinea capitis patients at a clinic in Surabaya, finding that the condition predominantly affected young males and was often associated with contact with cats.
research Les Rencontres d’Experts du Psoriasis : des recommandations pour la pratique quotidienne
This study found that tofacitinib was well tolerated and led to clinical improvement in 77% of potential responders with severe alopecia areata, alopecia totalis, or alopecia universalis.
research 43225 Randomized study to assess the efficacy of a facial cosmetic product with nanoencapsulated cysteamine in women presenting melasma
In this study, a cosmetic product with nano encapsulated cysteamine plus sunscreen significantly improved melasma symptoms and quality of life in adult women over 84 days, compared to sunscreen alone, without any medically relevant intolerance.
research An urticarial drug eruption caused by tofacitinib for alopecia universalis
A patient with alopecia had hair regrowth with tofacitinib but developed a skin reaction, choosing to continue the treatment despite the side effect.
research Responses to Tetanus and Meningococcal Vaccines in Patients with Alopecia Areata Treated with Ritlecitinib
This study found that patients with alopecia areata receiving ritlecitinib showed immune responses to meningococcal and tetanus vaccines, achieving significant antibody levels after vaccination, and no vaccine-related adverse events or disease exacerbations were reported despite a small sample size.
research Mealworm-Derived Protein Hydrolysates Enhance Adipogenic Differentiation via Mitotic Clonal Expansion in 3T3-L1 Cells
This study found that protein hydrolysates from mealworms, especially those derived using flavourzyme, significantly enhance adipogenic differentiation in 3T3-L1 preadipocytes, suggesting their potential as sustainable ingredients for glycemic control, skin health, and tissue regeneration products.
research Hepatocyte growth factor combined with adenosine deaminase as biomarker for diagnosis of tuberculous pleural effusion
HGF combined with ADA is highly accurate for diagnosing tuberculous pleural effusion, especially in younger females.
research Full‐body skin examination in screening for cutaneous malignancy: A focus on concealed sites and the practices of international dermatologists
This study suggests that establishing international consensus guidelines for including concealed or sensitive sites in routine forensic examinations is crucial to clarify clinician responsibilities, guide patient expectations, and reduce potential medicolegal issues.
research Comprehensive Safety Exposure‐Response Analysis to Support Ritlecitinib Dose Selection
This study examined the safety profile of ritlecitinib, a drug for alopecia areata, and found that it does not cause significant QTc prolongation or severe lymphopenia, with no unique safety risks expected in adolescents.
research Hepato- and neuro-toxicity by ethylenthiourea.
This study observed that ethylenthiourea's lethality increases with dose accumulation and ethanol co-administration, while impaired liver function and various adverse effects were noted in long-term treated rats.
research Cell-free fat extract restores hair loss: a novel therapeutic strategy for androgenetic alopecia
This study found that cell-free fat extract (CEFFE) enhanced hair growth in mice with androgenetic alopecia by increasing hair follicle density and promoting proliferation while regulating the DHT/AR pathway.
research Dermatophytosis in Cats
This review discusses the infection dermatophytosis in cats and reports no new results; it emphasizes the difficulty of eradicating the disease in shelters and catteries.
research Combination of Systemic and Topical Treatment for Feline Dermatophytosis: A Case Report
In this case study, a Persian cat with dermatophytosis showed a reduction in skin lesions after being treated with oral itraconazole and topical ketoconazole.
research Efficacy and safety of a new clobetasol propionate 0.05% foam in alopecia areata: a randomized, double‐blind placebo‐controlled trial
In this study, clobetasol propionate foam demonstrated effectiveness and good patient compliance as a safe topical treatment for moderate to severe alopecia areata, with significant hair regrowth compared to placebo.
research Oclacitinib Treatment and Surgical Management in a Case of Periocular Eosinophilic Furunculosis and Vasculitis with Secondary Eyelid Fusion in a Diabetic Cat
In this case study, a neutered British Shorthair cat with diabetes mellitus showed fast remission of facial skin issues using off-label oclacitinib, with no recurrence for 17 months, but required surgery for eyelid cicatrization.
research An Excellent Response to Tofacitinib in a Pediatric Alopecia Patient: A Case Report and Review.
This case report documented successful full hair regrowth in an 8-year-old with alopecia universalis after oral tofacitinib treatment, but mild headaches led to discontinuation.
research Characterization of Primary Cilia and Intraflagellar Transport 20 in the Epidermis
This study found that Ift20 is essential for hair follicle stem cell identity and hair regrowth, and it regulates keratinocyte migration during wound healing through focal adhesion integrin recycling, independently of ciliogenesis.
research Complexo granuloma eosinofílico felino: Relato de caso
This case report discusses a 5-year-old Persian cat with feline eosinophilic granuloma complex, which responded positively to prednisone and topical corticosteroids, eliminating itching and promoting fur regrowth without relapse.