Oclacitinib Treatment and Surgical Management in a Case of Periocular Eosinophilic Furunculosis and Vasculitis with Secondary Eyelid Fusion in a Diabetic Cat

A 10-year-old diabetic British Shorthair cat presented with severe facial and periocular skin issues, including swelling, erythema, alopecia, and ulcerations. Histopathology identified eosinophilic furunculosis and vasculitis. Initial glucocorticoid treatment improved symptoms but increased glucose levels, making systemic glucocorticoids and ciclosporin unsuitable. Instead, oclacitinib was used off-label, leading to rapid symptom remission with no recurrence for 17 months. Surgical intervention was required to correct secondary eyelid fusion due to cicatrization, restoring full eyelid function.