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New CRISPR/Cas9 variants and nanotechnology-based delivery methods are improving cancer treatment, but choosing the best variant and overcoming certain limitations remain challenges.

Enzymes called 5α-reductases have many body functions and need more research to safely use inhibitors.

Men and women get COVID-19 at similar rates, but men tend to get sicker and have a higher risk of dying, while women usually have stronger immune responses and vaccine reactions.

Topical corticosteroids are the main treatment for Erosive Pustular Dermatosis, but recurrence is common after stopping treatment.

Testosterone and its metabolites affect brain functions and could help treat neurological disorders.

Thymoma-associated multiorgan autoimmunity can cause liver damage and affects multiple organs, with limited treatment options and a generally poor prognosis.

Belimumab reduces disease activity, steroid use, and flares in lupus patients.

Plant steroid hormones show growth, health, and medicinal benefits in various organisms, including potential for treating diseases.

A girl with lupus and trisomy X has a higher risk of bone problems like avascular necrosis and osteoporosis.

New mouse models of Pemphigus show severe symptoms and need better treatments.

A woman with lupus had blood cell destruction, treated successfully with medication.

Allopregnanolone increases growth and changes gene activity in human brain cancer cells.

NcoA4 may have roles beyond helping control gene activity, possibly affecting cell behavior and stability.

Hirsute women have lower type 2 17β-HSD enzyme levels, which improve with treatment.

The study created a model to help design new inhibitors for steroidal 5α-reductase enzymes.

Male hormones and their receptors play a key role in hair loss and skin health, with potential new treatments being explored.

The protein StAR is found in 17 different organs and can affect hair loss and brain functions, but its full role is not yet fully understood.

Changes in skin microbes play a role in some skin diseases and could lead to new treatments.

Hormones and neuroendocrine factors control hair growth and color, and more research could lead to new hair treatment options.

Androgen is important in controlling stem cell differentiation, reducing fat development, and increasing lean mass.

Retinoids increase steroid sulfatase activity in leukemia cells through RARα/RXR and involves certain pathways like phosphoinositide 3-kinase and ERK-MAP kinase.

Micrografts promote hair growth in androgenetic alopecia treatment.

Finasteride improves heart function and repairs damage after heart attack in mice.

Testosterone significantly affects sexual desire in both men and women, but its impact on women is more complex and influenced by psychological factors.

Blue light might help treat skin conditions by affecting the skin's bacteria.

Two enzymes regulate androgen receptor activity, affecting treatments for androgen insufficiency and benign prostatic hyperplasia.

Targeted cancer therapies often cause serious skin problems that need careful management.

Androgen receptors are key for development and health, affecting conditions like prostate cancer and male pattern baldness.

Neurosteroids change how GABA_A receptors work in the brain, which could be important for treating temporal lobe epilepsy.