Skin stem cells are crucial for maintaining and repairing skin, with potential for treating skin disorders and improving wound healing.
April 2016 in “Journal of Investigative Dermatology” The symposium showed that stem cells are key for understanding and treating skin diseases and for developing new skin models and therapies.
November 2013 in “Elsevier eBooks” Skin and hair renewal is maintained by both fast and slow cycling stem cells, with hair regrowth primarily driven by specific stem cells in the hair follicle bulge. These cells can also help heal wounds and potentially treat hair loss.
September 2013 in “Experimental Dermatology” The document concluded that stem cells are crucial for skin repair, regeneration, and may help in developing advanced skin substitutes.
November 1966 in “British Journal of Dermatology” The meeting discussed various skin conditions, treatments, and unusual cases, highlighting the effectiveness of tetracycline in treating rosacea.
January 2008 in “The Year book of dermatology” After skin injury, adult mice can grow new hair follicles, and this process can be increased or stopped by manipulating Wnt signals.
1039 citations,
February 2009 in “Nature Reviews Molecular Cell Biology” Skin stem cells are crucial for maintaining and repairing the skin and hair, using a complex mix of signals to do so.
218 citations,
January 2013 in “The Lancet Oncology” Chemotherapy causes hair loss by damaging hair follicles and stem cells, with more research needed for prevention and treatment.
41 citations,
September 1991 in “Medical hypotheses” Prolactin may be important for skin growth and immune function.
39 citations,
April 2015 in “Regeneration” Lizards can regrow their tails, and studying this process helps understand scar-free healing and limb regeneration.
32 citations,
April 2013 in “Anais Brasileiros de Dermatologia” The document concludes that inherited epidermolysis bullosa is a challenging genetic condition requiring multidisciplinary care and new treatments.
29 citations,
January 2007 in “American Journal of Clinical Dermatology” Eyebrow loss has many causes and requires accurate diagnosis for proper treatment.
28 citations,
January 2013 in “Stem cells” Certain human skin cells marked by CD44 and ALDH are rich in stem cells capable of long-term skin renewal.
12 citations,
March 2011 in “Journal of pathology” Oncogenic K-ras causes rapid cancerous changes in the mouth's lining.
8 citations,
June 2019 in “Scientific Reports” Increased PPARGC1α relates to hair thinning in common baldness.
2 citations,
September 2017 in “Biotechniques/BioTechniques” Researchers created a mouse cell line to study hair growth and test hair growth drugs.
July 2022 in “Biomedicines” 4-Aminopyridine improves skin wound healing and tissue regeneration by increasing cell growth and promoting nerve repair.
January 2019 in “Springer eBooks” Transplanting skin cells is a safe, effective, and affordable treatment for vitiligo.
Chrysanthemum zawadskii extract may help treat hair loss by promoting hair growth and affecting growth factors.
489 citations,
November 2021 in “Signal Transduction and Targeted Therapy” The JAK/STAT pathway is important in cell processes and disease, and JAK inhibitors are promising for treating related conditions.
April 2016 in “Journal of Investigative Dermatology” Autophagy, a cell recycling process, is crucial for prolonged hair growth and could be a potential target for treating hair growth disorders.
33 citations,
January 2001 in “Critical care clinics” Dietary lipids affect inflammation and are crucial for normal cell function and immune health.
9 citations,
June 2016 in “Stem cells” Overexpression of sPLA2-IIA in mouse skin reduces hair stem cells and increases cell differentiation through JNK/c-Jun pathway activation.
78 citations,
August 2002 in “Experimental Dermatology” Researchers developed a quick and easy way to get and grow cells from the base of human hair follicles.
1 citations,
January 2024 in “Theranostics” Exosomes show promise for future tissue regeneration.
326 citations,
February 2009 in “The American journal of pathology” Lgr5 is a marker for active, self-renewing stem cells in the intestine and skin, important for tissue maintenance.
55 citations,
October 2019 in “The journal of allergy and clinical immunology/Journal of allergy and clinical immunology/The journal of allergy and clinical immunology” The review suggests that other immune cells besides CD8+ T cells may contribute to alopecia areata and that targeting regulatory cell defects could improve treatment.
2 citations,
August 2022 in “Emergency medicine international” Keloid skin disorder involves abnormal fibroblast activation and immune response, linked to a group of genes including FGF11.
1 citations,
August 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Certain cells in the adult mouse ear come from cranial neural crest cells, but muscle and hair cells do not.
April 2021 in “Journal of Investigative Dermatology” The research found genes that may protect certain scalp cells from hair loss.