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This review highlights recent advances in understanding how the extracellular matrix regulates epidermal stem cell fate, emphasizing the importance of the hair follicle stem cell niche, but reports no new empirical findings.

This research found that the microtubule catastrophe factor KIF18B plays a crucial role in promoting spindle orientation in keratinocytes, linking this process to cell fate decisions during hair follicle morphogenesis.

In this study, researchers identified a number of differentially expressed genes that may influence wool growth in Aohan fine wool sheep, offering insight into the genetic regulation of wool quality and yield.

This study identified significant gene expression differences in human basal cell carcinoma, including up-regulation of zinc finger encoding genes, which are not entirely reflected in current mouse models.

This review discusses how circadian clocks may influence diverse physiological functions beyond their established role in daily timekeeping, but it reports no new experimental findings.

This study found that the proteins Par3, mInsc, and Gαi3 cooperate to regulate LGN polarization and promote perpendicular cell divisions during murine epidermal morphogenesis.

This study used a probabilistic Boolean network model to explore hair follicle cell fate regulation and predicted that varying TGF-β levels, in coordination with BMP and TNF, can influence either apoptosis or cell proliferation during different follicle growth stages.

In this study, loss of epidermal Par3 in mice disrupted the skin barrier and affected cell differentiation and stem cell maintenance, highlighting its role in epidermal homeostasis.

This review concluded that chronic inflammation can lead to persistent activation of stem cells, accumulating DNA damage and promoting cancer development and metastasis from stem cell origins.

This review highlights that chronic inflammation leads to ongoing activation of stem cells, causing DNA damage accumulation, which can promote cancer development and metastasis.

In this review, researchers concluded that chronic inflammation perpetually activates stem cells, allowing DNA damage accumulation and potentially promoting cancer development and metastasis by converting stem cells into cancer cells.

This literature review reports that chronic inflammation can lead to persistent activation of stem cells, accumulating DNA damage, and eventually promoting cancer development and metastasis even before stem cells become cancerous.

This review concludes that chronic inflammation can lead to persistent activation of stem cells, which may accumulate DNA damage and ultimately promote cancer, while also facilitating cancer metastasis.

This review concludes that chronic inflammation persistently activates stem cells, leading to DNA damage accumulation that can promote cancer development and metastasis, affecting both stem and cancer cells.

This study observed that in adult mice, a cell-autonomous size control mechanism involving the RB pathway determines the timing of S phase entry in epidermal stem cells based on their size, while external microenvironment factors influence growth rates but not this intrinsic coupling.

This study observed that, in mouse ear epidermal stem cells, a cell-autonomous size control mechanism involving the RB pathway dictates S phase entry timing based on cell size, despite external environmental variations affecting growth rates.

This review discusses the structure, expression, regulation, and potential roles of NcoA4 in cancer and other pathologies, reporting no new experimental findings.

This study found that Wnt signaling regulates the symmetric division of adult neural stem cells, increasing their numbers during subependymal regeneration, stroke response, and colony formation.

The researchers reported that exposure to long days after short-day treatment induced a synchronized, out-of-season wool growth cycle in New Zealand Wiltshire sheep, similar to cycles induced in other species.

The conclusion is that the dermal papilla is crucial for hair follicle regrowth, and hair follicles undergo significant structural changes in addition to cell division during regeneration.

This research reexamined transcriptomic data to study stem and progenitor cell proliferation in psoriasis, finding that the number of committed progenitor cells increased eight-fold in psoriatic skin without altering stem cell numbers, potentially identifying new therapeutic targets.

This review discusses the mechanisms governing epidermal stem and progenitor cell differentiation, emphasizing the balance necessary for maintaining skin barrier function, and reports no new experimental findings.

This study found that inducing miR-205 reduces actin contractility and stiffness in hair follicle stem cells and progenitors, stimulating hair regeneration in both young and old mice.

This study found that dermal papilla cells from different scalp regions of AGA patients showed differential gene expression related to cell proliferation, apoptosis, and signaling pathways when exposed to DHT in a 3D culture.

This study found that loss of integrin-β4 or its ligand, laminin-α3β3ɣ2, in keratinocytes increases differentiation via delamination, and demonstrated a role for hemidesmosomes in epidermal differentiation through both mitotic and non-mitotic mechanisms, influenced by Notch signaling.

This study found that mammary resident macrophages regulate mammary epithelium cell division and development, with implications for maintaining mammary stem cell activity and homeostasis.

This study found that mouse hair follicle stem cells use symmetric cell division for maintenance and fate determination, and identified Gata6 as a crucial factor for their differentiation.

This review evaluates methods to study stem cell division patterns, particularly in the mammary gland, and discusses genetic factors affecting division modalities and their implications for breast cancer, but reports no new results.

This study found that bikunin is expressed in human keratinocytes and may play a role in regulating keratinocyte function during mitosis or inflammation.

This thesis explores the role of the actin cytoskeleton in plant cell growth, highlighting its involvement in signal transduction and the regulation of tip growth in cells like root hairs.