Search

everythinglearnresearchcommunity

for

Search:↓

Chemotherapy and radiation therapy cause skin and hair damage by altering gene expression and signaling pathways.

Early and late matrix progenitors in hair follicles create different cell layers, with early ones forming the companion layer and later ones forming the inner root sheath and hair shaft.

Sweat glands and hair follicles are determined by opposing signals, with BMPs promoting sweat glands and blocking BMPs leading to hair follicles.

The study found a link between the severity of Lichen Planopilaris seen by doctors and the details seen under a microscope, and created a new way to measure this severity.

A man with a rare skin condition and a new gene mutation developed high calcium levels due to his treatment.

The conclusion is that a certain test might help find cancer spread in lymph nodes for melanoma patients, but more research is needed due to false positives.

The document concludes that Borrelia afzelii causes a skin condition in France, a gene is linked to hair loss in Caucasian women, and various genetic mutations affect skin diseases.

Most studies on perioral dermatitis treatment are of low quality, with some agreement on oral tetracycline effectiveness and stopping steroids and cosmetics.

Dermagraft and Dermalogen had a lot of granulation, while Alloderm, Integra, and ADM had good blood vessel growth for skin healing.

The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.

Lgr5 is a marker for active, long-lasting stem cells in mouse hair follicles.

Hair follicles can regrow in wounded adult mouse skin using a process like embryo development.

VEGF helps hair grow and determines follicle size by increasing blood vessel growth.

Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.

Fat-related cells are important for initiating hair growth.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

Anabolic steroids can build muscle and strength but have risks and need more research on their clinical benefits and side effects.

Understanding gene expression in hair follicles can reveal insights into hair growth and disorders.

People with hair loss have more androgen receptors and enzymes in certain follicles, with men and women showing different patterns.

Understanding phenotypic plasticity is crucial for developing effective cancer therapies.

Prostate cancer cells can make their own androgens to activate the androgen receptor, and treatments like abiraterone may increase this ability, suggesting new therapies should target the entire steroid-making pathway.

Corticosteroids, especially prednisone, improve short-term muscle strength in Duchenne muscular dystrophy but have manageable side effects.

Hair and nail cells share similar proteins, indicating a common differentiation pathway.

Basal cell carcinoma mostly starts from cells in the upper skin layers, not hair follicle stem cells.

Human skin can make serotonin and melatonin, which help protect and maintain it.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

Super-enhancers controlled by pioneer factors like SOX9 are crucial for stem cell adaptability and identity.

β-catenin in the dermal papilla is crucial for normal hair growth and repair.

The conclusion is that certain cell interactions and signals are crucial for hair growth and regeneration.

The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.