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In an animal study, researchers observed that a newly synthesized deoxycholic acid derivative showed similar prostate protection effects to finasteride in Wistar rats while being less toxic.

This study found that the Plcd3(mNab) mutation in mice worsens the alopecia caused by Plcd1 loss, suggesting synergistic effects between Plcd1 and Plcd3 on hair follicle health.

This study found that oxybenzone is very stable under light exposure, contradicting previous findings of its oxidation to semiquinone after solar irradiation.

In this study, the researchers observed that both standard body and facial depilatory creams caused significant skin injury in mice, with varying effects depending on the mouse strain and exposure time, although both formulations were effective for hair removal.

In this study, rat vibrissa follicles transplanted into mice demonstrated survival, partial sympathetic nerve reinnervation, and increased norepinephrine levels 37 days post-implantation, suggesting potential for hair growth despite not returning to normal nerve function.

This study found that Zizyphus jujuba essential oil enhanced hair growth in mice, with the 1% and 10% concentrations showing increased hair length compared to control.

This study found that FGF21 suppresses inflammation induced by C. acnes in both human skin cells and mouse models, suggesting potential use in acne treatment.

In this study, metal-organic frameworks modified with stearic acid were used to deliver cardamonin to hair follicles, significantly promoting hair growth and cell proliferation in testosterone-challenged mice, suggesting potential benefits for androgenic alopecia treatment.

This study found that systemic ovalbumin–aluminum sensitization followed by cutaneous challenge in mice induced thermal hyperalgesia, increased spinal cord gliosis, and sprouting of nociceptive fibers, along with elevated mast cell and nerve profile densities in the skin compared to controls.

The researchers reported that the petroleum ether extract of Cuscuta reflexa may promote hair growth in testosterone-induced alopecia in mice by inhibiting the enzyme 5α-reductase.

This study found that the antidepressant-like effect of fluoxetine in mice was only observed when a 5-minute pretest session was conducted, and this effect was blocked by the TSPO antagonist PK11195.

In this study, the researchers report that a modified epimorphin-derived peptide shows potential for hair follicle regeneration, especially when used with 1% minoxidil in mice.

In a study using a mouse model of diabetes, chitosan-based hydrogels increased healing markers and improved wound closure and tissue repair compared to untreated wounds, but human efficacy needs further validation.

This study found that the effectiveness of 17-beta-estradiol in inhibiting hair growth depends on its application method, and noted significant sex differences in response to 17-alpha-estradiol in male and female mice.

This study found that mirex and TPA promote papilloma formation in CD-1 mouse skin through distinct populations of mutant Ha-ras cells, resulting in additive tumor yields.

This research observed that the skeletal abnormalities in Noggin null mice varied based on genetic background, and identified haploinsufficiency leading to joint fusions, similar to human conditions associated with NOGGIN deficiency.

This meta-analysis suggests that stem cell therapy may reduce burn wound area and improve healing-related factors in preclinical models, indicating potential for future clinical studies on burn treatment.

This study found that intradermal injections of Profhilo® significantly reduced skin inflammation and pain, while altering spinal cord markers in mice with ovalbumin-induced atopic dermatitis, suggesting potential therapeutic benefits for inflammatory skin conditions involving both peripheral and central processes.

This study observed that female mice with disrupted 5α-reductase 1 showed increased insulin resistance and hepatic steatosis, suggesting altered glucocorticoid metabolism contributes to metabolic disorders.

This study found that human skin grafted onto certain immunodeficient mice resulted in proliferative scars with characteristics similar to human hypertrophic scars, suggesting these models may better represent the condition's natural history.

This study found that inhibiting AP-1 activity in mice can induce lineage transdifferentiation between squamous and sebaceous tumors, suggesting AP-1's role in maintaining tumor cell identity.

This study found that inhibiting AP-1 transcription factors in mice causes squamous tumors to transform into sebaceous tumors and regulates tumor cell lineage.

In this study, NM exposure in mouse skin disrupted pilosebaceous units, initially decreasing markers of sebum production and cellular division, but showed signs of healing and marker recovery by day five.

Mast cells and VEGF contribute to post-surgery adhesions, and blocking VEGF can reduce these adhesions; also, certain factors affect wound healing and fetal skin heals differently with age.

This study found that papillary dermal fibroblast progenitors in newborn mouse skin can be isolated and cultured to generate male germline cell precursors, demonstrating their potential through differentiation into cells with meiotic capability.

In a study using mouse models, researchers developed a gelatin methacryloyl scaffold with calcium-doped silica nanoparticles loaded with deferoxamine, which significantly improved skin flap survival and hair follicle growth, suggesting potential clinical applications in tissue regeneration.

This study did not find any significant effects of estradiol or its antagonists on hair growth in two common mouse strains, challenging previous results reported by Oh and Smart.

This study found that using a Picosecond IR Laser (PIRL) on mouse skin led to less tissue damage and scarring compared to conventional surgical lasers and tools.

This study found that Rumex japonicus extract may help reduce symptoms of atopic dermatitis by inhibiting inflammatory responses in both cell cultures and a mouse model.

This study concludes that egg shell membrane hydrolysates, particularly Fraction I, may effectively mitigate UV-B radiation-induced wrinkles and promote skin collagen and hyaluronic acid production, suggesting potential use in functional cosmetics.