research Somatostatin Expression in Human Hair Follicles and Its Potential Role in Immune Privilege
Somatostatin may help protect hair follicles from immune attacks.
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research Analysis of Hidradenitis Suppurativa-Linked Mutations in Four Genes and the Effects of PSEN1-P242LfsX11 on Cytokine and Chemokine Expression in Macrophages
The document concludes that certain mutations may contribute to the inflammation in hidradenitis suppurativa and suggests that targeting TNFα could be a treatment strategy.
research Bendamustine in Indolent Non-Hodgkin's Lymphoma: A Practice Guide for Patient Management
Bendamustine combined with rituximab is an effective and well-tolerated treatment for certain types of lymphoma.
research Diffuse Alopecia Areata Is Associated With Intense Inflammatory Infiltration and CD8+ T Cells in Hair Loss Regions and an Increase in Serum IgE Level
Diffuse alopecia areata involves more inflammation and higher allergy-related antibodies than patchy types.
research Alopecia Areata Presenting in Two Kidney-Pancreas Transplant Recipients Taking Cyclosporine
Two transplant patients on cyclosporine unexpectedly developed hair loss.
research An Update of the Pathogenesis of Frontal Fibrosing Alopecia: What Does the Current Evidence Tell Us?
The current understanding of frontal fibrosing alopecia involves immune, genetic, hormonal factors, and possibly environmental triggers, but more research is needed for effective treatments.
research Alopecia in Rhesus Macaques Correlates with Immunophenotypic Alterations in Dermal Inflammatory Infiltrates Consistent with Hypersensitivity Etiology
Hair loss in Rhesus macaques may be caused by a skin allergy-related condition.
research Alopecia Areata: Gene Expression in Skin Samples from Patients
Alopecia areata involves immune response and gene changes affecting hair loss.
research Sebaceous Immunobiology: Skin Homeostasis, Innate Immunity Coordination, Inflammatory Response, and Disease Associations
Sebaceous glands play a key role in skin health, immunity, and various skin diseases.
research Disease Versus Disease: How One Disease May Ameliorate Another
Some diseases can improve the outcomes of other diseases, leading to new treatment possibilities.
research The Use of Mesenchymal Stromal Cells in the Treatment of Coronavirus Disease 2019
Mesenchymal stromal cells may help treat severe COVID-19, but more research is needed to confirm their effectiveness.
research Teriflunomide in Multiple Sclerosis: An Update
Teriflunomide effectively reduces relapses and disability in MS and has a manageable safety profile.
research Total Glucosides of Paeony Capsule Plus Compound Glycyrrhizin Tablets for the Treatment of Severe Alopecia Areata in Children: A Randomized Controlled Trial
TGPC plus CGT is effective and safe for treating severe alopecia areata in children.
research IL-12/IL-23 Neutralization Is Ineffective for Alopecia Areata in Mice and Humans
Blocking IL-12/IL-23 does not help with hair loss in alopecia areata for mice or humans.
research Modeling Cell-Cell Communication for Immune Systems Across Space and Time
The document concludes that computational models are useful for understanding immune responses and could improve cancer immunotherapy.
research Advances in Psoriasis Therapy
New psoriasis treatments are effective but come with side effects and risks.
research Distinctive Lupus Panniculitis of Scalp with Linear Alopecia Along Blaschko's Lines: A Review of the Literature
Lupus panniculitis of the scalp causes linear hair loss and needs ongoing treatment to prevent recurrence and lupus.
research Differential Proteomics of Lesional vs. Non-Lesional Biopsies Revealed Non-Immune Mechanisms of Alopecia Areata
Non-immune factors play a significant role in alopecia areata.
research The Histopathology of Alopecia Areata in Vertical and Horizontal Sections
Horizontal scalp biopsy sections are better for diagnosing alopecia areata, showing fewer hair follicles and more miniaturized hairs.
research Epidermal Stem Cells in Hair Follicle Cycling and Skin Regeneration: A View From the Perspective of Inflammation
Inflammation plays a key role in activating skin stem cells for hair growth and wound healing, but more research is needed to understand how it directs cell behavior.
research Sequential High- And Low-Dose Systemic Corticosteroid Therapy For Severe Childhood Alopecia Areata
High and low doses of prednisolone helped 62% of children with severe alopecia regrow hair with some weight gain and mild acne as side effects.
research FOXN1 Italian Founder Mutation in Indian Family: Implications in Prenatal Diagnosis
A rare genetic mutation found in an Indian family can be detected through prenatal screening.
research Identification of an Intronic Regulatory Element Necessary for Tissue-Specific Expression of Foxn1 in Thymic Epithelial Cells
A specific DNA region is crucial for Foxn1 gene expression in thymus cells but not in hair follicles.
research Implication of Human Bacterial Gut Microbiota on Immune-Mediated and Autoimmune Dermatological Diseases and Their Comorbidities: A Narrative Review
An imbalance in gut bacteria is linked to skin immune diseases and may affect their outcomes and related health issues.
research What's New in Cicatricial Alopecia?
New treatments and early diagnosis methods for permanent hair loss due to scar tissue are important for managing its psychological effects.
research Hair Follicles and Their Role in Skin Health
Hair follicles are essential for skin health, aiding in hair growth, wound healing, and immune function.
research Localized Cutaneous Necrosis Associated with the Antiphospholipid Syndrome
A woman with lupus experienced skin death due to a blood clotting disorder after stopping a blood thinner, which healed with treatment.
research Stem Cell Apoptosis in HIV-1 Alopecia
HIV-1 may cause increased stem cell death in hair follicles, leading to hair loss.
research Contact Dermatitis to Phenol-Formaldehyde Resin in Two Plywood Factory Workers
Two plywood factory workers developed contact dermatitis from phenol-formaldehyde resin, a known allergen.
research The Effect of Active Hexose Correlated Compound in Modulating Cytosine Arabinoside-Induced Hair Loss, and 6-Mercaptopurine- and Methotrexate-Induced Liver Injury in Rodents
AHCC reduces hair loss and liver injury caused by chemotherapy in rodents.