This study reviewed and reclassified 37 cases of primary scarring alopecia using histological methods to achieve more accurate diagnoses within subtypes like lupus erythematosus and lichen planopilaris.
5 citations
,
November 2005 in “Journal of Investigative Dermatology”
April 2026 in “Institutional Repositories DataBase (IRDB)” This study investigated human hair follicle bulge cells and found that those with reduced CD200 expression exhibited enhanced hair regenerative capability, refining the functional understanding of bulge cell heterogeneity and providing insights for optimizing bulge cell–based hair regeneration techniques.
November 2006 in “評価・診断に関するシンポジウム講演論文集” This study found that KSR1 is essential for v-Ha-ras-mediated skin tumor formation in mice but not for MT-driven mammary tumor genesis, suggesting its potential as a therapeutic target in Ras/MAPK signaling.
April 2026 in “Frontiers in Cell and Developmental Biology” This study found that CD200-negative human hair follicle bulge cells have a higher hair-regenerative capability compared to CD200-positive cells, suggesting that reduced CD200 expression may enhance hair regeneration, providing insights for improving bulge cell-based hair restoration techniques.
12 citations
,
November 2007 in “Journal of Investigative Dermatology” CD200 is not a reliable marker for identifying stem cells in all skin types.
1 citations
,
May 2019 in “Cytotherapy” This study found that digital droplet PCR (ddPCR) outperformed qPCR in detecting replication competent lentivirus in CAR-T products by offering better sensitivity, specificity, and reproducibility, making it a reliable and rapid method for ensuring patient safety.
May 2026 in “Chemical Engineering Journal”
November 2018 in “Annals of oncology” This study found that the computer-controlled RV-01 scalp cooling device helped prevent significant hair loss in metastatic breast cancer patients treated with eribulin, with none of the 16 patients requiring a wig and experiencing minimal discomfort.
8 citations
,
January 2023 in “RSC Advances” This article reviews advancements in carbon dots for tissue engineering and regenerative medicine, highlighting challenges and future directions without presenting new clinical findings.
September 2023 in “Journal of the American Academy of Dermatology” January 2024 in “Wiadomości Lekarskie” This pilot clinical study introduces DEC cells as a novel therapy for Duchenne muscular dystrophy, confirming safety and efficacy in seven patients up to 24 months post-treatment.
15 citations
,
January 2024 in “The AAPS Journal” This study demonstrates that bioequivalence for proposed 50-mg ritlecitinib capsules versus clinical 100-mg capsules can be supported using a PBPK model-based biowaiver, achieving over 90% probability of success.
147 citations
,
October 2021 in “Cancer Communications” This study found that the novel anti-HER2 antibody RC48 demonstrated promising activity and manageable safety in patients with HER2-overexpressing, advanced gastric or gastroesophageal junction cancer after at least two prior chemotherapy lines.
September 2017 in “Journal of Investigative Dermatology” RCS-01 is safe and may help rejuvenate aging skin.
5 citations
,
April 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” This study reports on an ongoing Phase I/IIa clinical trial of ex vivo gene therapy for treating severe Recessive Dystrophic Epidermolysis Bullosa, involving six adult participants with COL7A1 mutations resulting in deficient type VII collagen production.
July 2024 in “Journal of Investigative Dermatology” A new test helps find drugs to treat head and neck cancer by targeting c-Rel.
23 citations
,
September 2020 in “Journal of Dermatological Science” This pilot study suggests that skin-resident γδT-cells may play a significant role in the early stages of alopecia areata pathogenesis, indicating a potential new target for therapeutic management.
8 citations
,
July 2020 in “Clinical, cosmetic and investigational dermatology” This review hypothesizes that excessive facial photo-protection may contribute to frontal fibrosing alopecia by disrupting immunological homeostasis through the aryl hydrocarbon receptor-kynurenine pathway, but it reports no new clinical results.
50 citations
,
February 2007 in “The Journal of Pathology” This study found a rare germline mutation in the Birt–Hogg–Dubé gene in a Japanese patient with renal cell carcinoma, suggesting distinct biological features and challenging current renal tumor classifications.
20 citations
,
March 2019 in “Nutrients” This study found that Rumex japonicus extract may help reduce symptoms of atopic dermatitis by inhibiting inflammatory responses in both cell cultures and a mouse model.
5 citations
,
April 2020 in “Journal of Mind and Medical Sciences” This paper presents a new device for navigational surgery utilizing the fluorescent properties of Indocyanine Green, offering enhanced intra-operative imaging capabilities by identifying tissues with an infrared CMOS camera.
28 citations
,
September 2014 in “Journal of Veterinary Internal Medicine” This study found that the novel drug VDC-1101 showed a 45% objective response rate in treating canine cutaneous T-cell lymphoma, offering a potential treatment option for this challenging disease.
18 citations
,
August 2015 in “Biochemical and Biophysical Research Communications” This study found that the XEDAR receptor can activate the non-canonical NF-kB pathway involving p100 processing, which is regulated by interactions with TRAF proteins and specific kinases.
July 2024 in “Journal of Investigative Dermatology” CRISPR/Cas9 and prime editing can potentially fix skin disorder genes safely and effectively.
9 citations
,
October 2022 in “Nature Communications” In this study, researchers developed a new photoactivatable Cre recombinase mouse model, DiLiCre, which allows precise light-induced genetic modifications and cell tracing, demonstrating its effectiveness for advancing biological and biomedical research.
7 citations
,
January 2014 in “Biological & pharmaceutical bulletin” This study found that rice bran oil extracted by supercritical CO2 can be considered non-genotoxic based on in vitro and in vivo test results, despite some chromosomal aberrations observed under specific conditions.
February 2026 in “Frontiers in Immunology” This review highlights the role of the brain–gut–skin axis in systemic inflammatory skin conditions, revealing potential interventions like microbiome-directed treatments and integrative therapies, though emphasizes the need for more robust clinical validation.
February 2024 in “International journal of molecular sciences” This study reviews current evidence on the role of ILC3s in the skin, highlighting their potential involvement in responding to microbiome changes such as those associated with acne and suggesting gaps in understanding their mechanisms.
2 citations
,
August 2014 in “Journal of dermatological science” This study found that krh/krh rats serve as a suitable model for non-inflammatory acne and that adapalene treatment decreased open comedones and altered lipid metabolism and cytokine production in these rats.