32 citations
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January 2017 in “Orphanet journal of rare diseases” This article reviews the genetic basis, diagnostic approaches, and treatment options for nude severe combined immunodeficiency, but does not present any new research findings.
13 citations
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February 2023 in “Aging” This study found that exosomes from hair follicle mesenchymal stem cells overexpressing lncRNA H19 promoted diabetic skin wound healing by enhancing cell proliferation, migration, and reducing pyroptosis.
52 citations
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February 2003 in “Archives of dermatology” In this open-label trial, 9-cis-retinoic acid showed moderate activity against Kaposi sarcoma in AIDS patients, but its use is limited by substantial side effects at higher doses.
55 citations
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November 2010 in “Journal of Allergy and Clinical Immunology” This study found that the TLR3 L412F genetic variant is associated with severe viral infections, especially CMV, and immune dysfunction in a subgroup of chronic mucocutaneous candidiasis patients.
May 2023 in “The Journal of Immunology” In this study, treatment with IL-2C to expand Tregs effectively halted hair loss progression in a murine model of alopecia areata.
13 citations
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August 2000 in “Blood” This article discusses the evaluation of minimal residual disease in childhood acute lymphoblastic leukemia using molecular methods and reports no new findings.
July 2020 in “Indian journal of sexually transmitted diseases and AIDS” This article highlights the importance of an algorithmic approach to manage multiple opportunistic infections in HIV-infected patients due to the risk of drug interactions and complications, but reports no new clinical results.
November 2020 in “Journal of The American Academy of Dermatology” This study examined dermoscopic features in African-American women with different types of alopecia and found that a perifollicular pink blush, potentially indicating inflammation, was common, particularly resolved with anti-inflammatory treatment, suggesting dermoscopy could aid in management.
April 2026 in “Current HIV Research” This study observed that despite advances with antiretroviral therapy, over half of patients with HIV continue to experience various skin disorders, highlighting the importance of ongoing dermatological assessment in their care.
4 citations
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April 2016 in “Journal of The American Academy of Dermatology” This case report details the first known instance of interferon-induced lichen planus in a seronegative HCV patient with metastatic renal cell carcinoma.
12 citations
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December 2021 in “Frontiers in Medicine” This study observed that dermatological patients using certain immunosuppressants, like azathioprine and high-dose prednisolone, had a reduced humoral immune response to the Sinovac-CoronaVac COVID-19 vaccine compared to those without such treatments.
30 citations
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April 2007 in “Journal of Leukocyte Biology” This study found that anti-CD44 treatment inhibited leukocyte migration in alopecia areata and eczema, suggesting targeted therapies could enhance contact sensitizer treatment for alopecia areata.
2 citations
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June 2025 in “Journal of Investigative Dermatology” CD8+ T cells re-expressing CD45RA may predict treatment resistance in severe alopecia areata.
9 citations
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March 2017 in “Journal of Visualized Experiments” This study introduced a novel in vitro murine assay using transgenic mice to identify immunomodulatory compounds, which identified 160 potential hits from 4,398 compounds screened.
1 citations
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July 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” In this open-label trial, Tofacitinib was well tolerated and improved IFN and cytokine scores, as well as overall skin pathology, in individuals with Down syndrome and immune skin conditions.
46 citations
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October 2018 in “JCI insight” In this study, the researchers found that treatment with the JAK inhibitor tofacitinib in alopecia areata patients may reduce clonal CD8+ T cell expansions but does not eliminate them entirely, which could contribute to disease relapse.
June 2017 in “The Medical Journal of Australia” This article provides no abstract or new research findings.
In this case study, donor lymphocyte infusions effectively eradicated measurable residual disease in a patient with relapsed acute myeloid leukemia after hematopoietic cell transplantation, while side effects included the development of vitiligo and alopecia areata, likely due to chronic graft-versus-host disease.
In this study, researchers identified IL18R+ thymus-resident regulatory T cells in mice, demonstrating their unique molecular features and resistance to age- and stress-induced thymus involution, highlighting IL18 signaling's role in Treg migration and retention.
February 2020 in “Oncology Times” This article reviews antibody drug conjugates for cancer treatment, describing their mechanism, recent approvals, and ongoing research efforts, but reports no new clinical results.
1 citations
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June 2020 in “Unisa Institutional Repository (University of South Africa)” This study found that low power red laser therapy, combined with antiretroviral drug efavirenz, significantly reduces HIV-1 infection in TZM-bl cells to undetectable levels.
39 citations
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May 2004 in “Clinics in Dermatology” This article reviews treatment options for cutaneous T-cell lymphoma, including skin-directed therapies and aggressive treatments for advanced cases, but reports no new clinical results.
November 2025 in “The Journal of Immunology” In a murine model of alopecia areata, this study observed that the IL-2 fusion protein HCW9302 helped prevent disease development by expanding regulatory T cells and reducing disease-causing effector T cell infiltrates, suggesting potential for using IL-2 fusion proteins in alopecia areata treatment.
2 citations
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June 2020 in “Research Square (Research Square)” This study demonstrated that the antiandrogen drug enzalutamide may reduce TMPRSS2 levels in human lung cells and mouse lungs, supporting its potential as a COVID-19 treatment option.
November 1998 in “Journal of The European Academy of Dermatology and Venereology” A man's skin cancer improved and some of his hair grew back after treatment with a special light therapy and a medication.
September 2024 in “Journal of the American Academy of Dermatology” PRO-C22 can help diagnose and monitor the severity of hidradenitis suppurativa.
October 2021 in “Journal of Investigative Dermatology” This study found no significant difference in the seroconversion rate of SARS-CoV2 IgG between patients with Immune Mediated Inflammatory diseases undergoing Targeted Immune-Modulating Therapies and those on conventional systemic treatment.
16 citations
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September 2020 in “Animals” This study found that circRNA-1926 promotes hair follicle stem cell differentiation in cashmere goats by sponging miR-148a/b-3p to increase CDK19 expression.
In this study, researchers analyzed over 5,000 T cells per sample using scRNA+TCR-seq technology and found that dual TCR Tregs are present in high proportions across various mouse tissues, showing unique TCR pairing patterns, V(D)J usage, and mRNA expression compared to single TCR Tregs.
107 citations
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December 2003 in “Dermatologic Therapy” This paper reviews the use of interferons, particularly alfa interferon, in treating cutaneous T-cell lymphoma, noting its substantial efficacy both alone and in combination therapies with predictable, generally well-tolerated side effects.