1 citations
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September 2025 in “Journal of Zhejiang University SCIENCE B” This abstract outlines the current understanding of cutaneous squamous cell carcinoma (cSCC), identifying it as the second most common non-melanoma skin cancer with risk factors like UV exposure and immunosuppression. It highlights cSCC's potential to metastasize and become fatal, affecting 2%-5% of in situ cases.
6 citations
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August 2016 in “Journal of Visualized Experiments” This article describes a method using the CUBIC protocol to clarify and visualize molecular and cellular interactions in mouse skin biopsies at single cell resolution, but does not provide new biological findings.
2 citations
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May 2023 in “JAAD Case Reports” This article discusses the lack of information on central centrifugal cicatricial alopecia's manifestations in Black men and reports no new clinical findings; the authors emphasize the need for further study in this population.
22 citations
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August 2015 in “Cochrane Database of Systematic Reviews” The study aims to find the best treatment for central serous chorioretinopathy by comparing various options.
January 2006 in “Chieh P'ou Hsueh Pao” This study established a method for selecting human hair follicle stem cells through quick-adherence to collagen, and found that β-catenin plays a role in their proliferation and differentiation.
March 2024 in “Research Square (Research Square)” In this study, scalp cooling therapy was found to be well tolerated and effective at improving hair preservation for Asian women with breast or gynecological cancers undergoing certain chemotherapy regimens, particularly weekly paclitaxel, compared to historical controls.
10 citations
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November 2018 in “Genetics in medicine” This study identified a genetic variant in the CTS6 gene associated with a hypotrichosis syndrome, emphasizing the significant role of cystatin M/E in hair and skin health.
1 citations
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December 2021 in “Tropical Journal of Pharmaceutical Research” This study concluded that adding Kanglaite injection to gemcitabine and cisplatin chemotherapy for advanced non-small cell lung cancer improved response rates and reduced adverse side effects.
January 2022 in “Clinical Cases in Dermatology” This review discusses the pathogenesis, diagnosis, and treatment strategies for Central Centrifugal Cicatricial Alopecia, emphasizing a multifactorial approach and reporting no new clinical results.
1 citations
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August 2024 in “Transgenic Research” In this study, the researchers observed that inducing and then withdrawing β-catenin expression in a bigenic mouse model caused reversible changes in skin morphology, indicating dependence on β-catenin signaling.
March 2024 in “Journal of Experimental & Biomedical Sciences/Biomedical Science Letters” In this study, BCC therapy reduced oxidative stress and cell damage in cardiomyocyte cells, suggesting it may serve as a new treatment alternative for heart disease.
2 citations
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June 2012 in “PubMed” This article reports three cases of African American men with central centrifugal cicatricial alopecia, highlighting the need to consider this diagnosis for male patients with vertex hair loss and scalp symptoms.
21 citations
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August 2002 in “British Journal of Ophthalmology” This article discusses topical and intralesional cidofovir use for SCC and suggests a successful outcome in one case, with no systemic toxicity observed so far.
29 citations
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September 2014 in “American Journal of Dermatopathology” This study found that horizontal sections of scalp biopsies in patients with Central Centrifugal Cicatricial Alopecia often reveal follicular miniaturization, inflammation, and scarring, which can guide personalized treatment.
28 citations
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November 2018 in “Journal of Cellular and Molecular Medicine” This review discusses the role of the CXXC5 protein as a transcription factor and signaling coordinator, noting its involvement in embryonic development, tissue homeostasis, and diseases such as tumorigenesis, but reports no new experimental findings.
September 2022 in “Medical Mycology” This study found that three protocols for generating Titan cells in vitro from Candida neoformans vary in their kinetics and transcriptomic profiles, pointing to differences which could impact further research.
14 citations
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May 2019 in “Human gene therapy” This study found that minicircle-based gene therapy significantly lowered total homocysteine levels and improved liver CBS activity in a mouse model of CBS deficiency.
December 2024 in “Chemical Senses” This study investigated Cronkhite-Canada syndrome in ten patients, finding severe taste abnormalities in the anterior tongue linked to tongue papillary atrophy, which improved with treatment. Taste function tests were helpful in evaluating treatment effectiveness for this rare disorder.
January 2024 in “Indian Journal of Psychiatry” This study found that precision 40Hz gamma-transcranial alternating current stimulation significantly improved negative and cognitive symptoms in patients with schizophrenia compared to a sham group, suggesting promising potential for this neuromodulation technique in treating these symptoms.
December 2024 in “Kırıkkale Üniversitesi Tıp Fakültesi Dergisi” This study found that chromosomal microarray analysis identified copy number variations in 12% of patients with dysmorphic features and congenital anomalies, demonstrating its potential as a diagnostic tool, especially for rare CNVs and immune deficiency linked to the deletion of CTLA4.
1 citations
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December 2023 in “JAAD International” Mast cells may significantly contribute to central centrifugal cicatricial alopecia.
January 2022 in “Mammalian Genome” This study found that the wavy coat trait in Nakano cataract mice is polygenic, involving major and minor genes, and resembles human curly scalp hair associated with the PRSS53 gene alteration.
10 citations
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August 2002 in “British Journal of Ophthalmology” This case study reports that intralesional cidofovir was successfully used for treatment without systemic toxicity, suggesting it might be an option worth considering for SCC.
March 2021 in “Arrow - TU Dublin (Technological University Dublin)” This study tested a folate-conjugate drug delivery system and found its cytotoxicity depends on whether the treated cells overexpress folate receptors, suggesting potential for targeted chemotherapy.
13 citations
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March 2020 in “Frontiers in cell and developmental biology” This study suggests that 3,4,5-tri-O-caffeoylquinic acid activates β-catenin to enhance pigmentation in mouse hair follicles, human melanocytes, and melanoma cells during the hair cycle's growth phase.
1 citations
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January 2024 in “International Journal of Epidemiology” This study describes the ongoing HABIT study in Taicang, China, which aims to identify risk factors and the relationship between cardiovascular and neurodegenerative diseases among 10,357 adults, by collecting and analyzing long-term data on health, lifestyle, and biological specimens. Results are not yet available.
December 2019 in “The American Journal of Gastroenterology” In this study, three cases of Cronkhite-Canada syndrome revealed small bowel mucosal lesions, but these findings did not correlate with clinical symptoms or steroid treatment outcomes.
May 2024 in “British journal of dermatology/British journal of dermatology, Supplement” The researchers reported increased ubiquitination of proteins such as the insulin receptor in CYLD cutaneous syndrome skin tumors, suggesting that CYLD dysfunction may affect protein secretion and signaling processes.
5 citations
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May 2008 in “Annals of saudi medicine/Annals of Saudi medicine” This case report from India observed that short-term cabergoline treatment brought clinical and biochemical remission in a 12-year-old with persistent Cushing disease after surgery and radiotherapy.
This study found that lysine carboxymethyl cysteinate helps protect the epidermis from UVB-induced damage by activating autophagy and restoring cornification processes in a skin model.