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The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

The skin's ability to produce hormones is linked to various skin conditions, and better understanding this process could lead to new treatments.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Small changes in hormones can significantly impact health, showing the importance of sensitive testing for chemicals that disrupt hormones.

Post-finasteride patients show changes in gut bacteria, possibly causing various symptoms.

People with polycystic ovary syndrome (PCOS) are more likely to have higher levels of depression and anxiety, but their personality traits are similar to those without PCOS.

The document concludes that Borrelia afzelii causes a skin condition in France, a gene is linked to hair loss in Caucasian women, and various genetic mutations affect skin diseases.

Bariatric surgery helps with weight loss but can cause complications and nutritional deficiencies.

ERULUS controls root hair growth by regulating cell wall composition and pectin activity.

Acne is linked to complex skin microbe interactions, and new findings suggest microbiome-based treatments could be effective.

Epidermal stem cells help heal severe skin wounds and have potential for medical treatments.

Biologics show promise in treating various stubborn skin diseases, but more research and better reimbursement criteria are needed.

Using rodents for research shows that health problems in the womb can cause diseases later in life.

COVID-19 can cause various skin issues, but long-term skin problems are rare.

A thorough diagnostic process and teamwork are crucial for managing complex hyperandrogenism in postmenopausal women.

Histone modification is key in treating chronic inflammatory skin diseases.

Hormones significantly affect hair and oil gland function in the skin, and more research is needed on skin-related hormone disorders.

Behavioral dermatology treats skin problems by considering both emotional and physical factors.

Most patients with Porphyria Cutanea Tarda had skin blisters and were often affected by hepatitis C and alcohol abuse, with differences between familial and sporadic cases.

Different skin cells process testosterone differently, and certain drugs can change this process, possibly helping treat acne and hair loss.

Immune checkpoint inhibitors can cause skin issues but are linked to better cancer outcomes.

Finasteride worsens stress effects on sensory processes, possibly linking to anxiety/depression.

Faulty inflammasome activation may lead to autoimmune skin diseases and could be a target for new treatments.

Certain genetic variations are linked to higher liver enzyme levels in patients treated for chronic hepatitis C with specific drugs.

Most cats with dermatophytosis had fungal infections, mainly caused by M. canis.

Keratin 18 helps diagnose and predict cancer progression and affects cancer growth and spread.

Excess androgens may cause PCOS, not just be a symptom.

Lymecycline may help with Frontal Fibrosing Alopecia but needs more research.

The Rotterdam Study aims to understand various diseases in older adults.

Targeting the IL-23/IL-17 pathway effectively treats several inflammatory skin diseases.