research Exploring the Versatility of Microemulsions in Cutaneous Drug Delivery: Opportunities and Challenges
Microemulsions could improve skin drug delivery but face challenges like complex creation and potential toxicity.
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150-180 / 495 results research Synthesis and Evaluation of Finasteride-Loaded HPMC-Based Nanogels for Transdermal Delivery: A Versatile Nanoscopic Platform
Finasteride-loaded nanogels are effective, safe, and improve drug absorption through the skin.
research Modulation of Electroosmotic Flow Through Skin: Effect of Polyamidoamine Dendrimers
Polyamidoamine dendrimers can change the strength and direction of electroosmotic flow through the skin, affecting drug delivery.
research Biomimetic Scaffolds: A Novel Approach to Three-Dimensional Cell Culture Techniques for Potential Implementation in Tissue Engineering
Biomimetic scaffolds are better than traditional methods for growing cells and could help regenerate various tissues.
research How Biodegradable Polymers Can Be Effective Drug Delivery Systems for Cannabinoids: Perspectives and Challenges
Biodegradable polymers can improve cannabinoid delivery but need more clinical trials.
research Life Sciences Discovery And Technology Highlights
New technologies show promise in healing wounds, treating cancer, autoimmune diseases, and genetic disorders.
research Triton Modified Polyethyleneimine Conjugates Assembled With Growth Arrest-Specific Protein 6 for Androgenetic Alopecia Transdermal Gene Therapy
The treatment effectively promotes hair regrowth in androgenetic alopecia without causing skin irritation.
research Biology of Human Hair: Know Your Hair to Control It
Understanding hair biology is key to developing better treatments for hair and scalp issues.
research Exogenous Factors in Hair Disorders
Outside factors like grooming, chemicals, and the environment can damage hair and cause disorders.
research Skin Regeneration: Strategies and Innovations
New materials and methods could improve skin healing and reduce scarring.
research Trends in Biopolymer Science Applied to Cosmetics
Biopolymers are increasingly used in cosmetics for their non-toxicity and skin benefits, with future biotech advancements likely to expand their applications.
research Nanostructured Lipid Carriers Promote Percutaneous Absorption and Hair Follicle Targeting of Tofacitinib for Treating Alopecia Areata
Nanostructured lipid carriers effectively deliver tofacitinib to hair follicles, reversing hair loss in alopecia areata.
research Development and Evaluation of Antisense shRNA-Encoding Plasmid Loaded Solid Lipid Nanoparticles Against 5-Alpha Reductase Activity
The new particle system could be a promising treatment for diseases related to the 5-α reductase enzyme.
research Delivery of Tissue-Targeted Scalpels: Opportunities and Challenges for In Vivo CRISPR/Cas-Based Genome Editing
Using CRISPR for gene editing in the body is promising but needs better delivery methods to be more efficient and specific.
research Prolactin: A Novel Neuroendocrine Regulator of Human Keratin Expression In Situ
Prolactin affects the production of different keratins in human hair, which could lead to new treatments for skin and hair disorders.
research Ultrasound-Activated Particles as CRISPR/Cas9 Delivery System for Androgenic Alopecia Therapy
Scientists have created a new hair loss treatment using ultrasound to deliver gene-editing particles, which resulted in up to 90% hair regrowth in mice.
research Physical Methods for Topical Skin Drug Delivery: Concepts and Applications
New physical methods like electrical currents, ultrasound, and microneedles show promise for improving drug delivery through the skin.
research Human Epithelial Stem Cell Survival Within Their Niche Requires Tonic Cannabinoid Receptor 1 Signaling—Lessons From the Hair Follicle
Cannabinoid receptor-1 signaling is essential for the survival and growth of human hair follicle stem cells.
research Self-Amplifying RNA Approach for Protein Replacement Therapy
Self-amplifying RNA could be a better option for protein replacement therapy with lower doses and lasting effects, but delivering it into cells is still challenging.
research Weekly Treatment with SAMiRNA Targeting the Androgen Receptor Ameliorates Androgenetic Alopecia
A new treatment called SAMiRNA-AR68 increases hair count in people with hair loss, showing similar results to existing treatments but without side effects.
research Prevention of Lipid Loss from Hair by Surface and Internal Modification
Surface and internal treatments can help prevent hair lipid loss during washing.
research Effect of Charge Carrier Lipid on Skin Penetration, Retention, and Hair Growth of Topically Applied Finasteride-Containing Liposomes
Anionic liposome formulations of finasteride may effectively treat hair loss with fewer side effects.
research Squarticles as Nanoantidotes to Sequester Overdosed Antidepressants for Detoxification
Tiny particles called anionic squarticles can effectively remove a common antidepressant from the body after an overdose.
research Comparison of Physical and Chemical Properties of Black and White Hair
White hair is denser and more hydrophobic than black hair.
research Penetration of Cationic Conditioning Compounds into Hair Fibers: A TOF-SIMS Approach
The study found that certain conditioning compounds can penetrate hair and potentially improve its resistance to damage.
research Applications and Limitations of Lipid Nanoparticles in Dermal and Transdermal Drug Delivery via the Follicular Route
Lipid nanoparticles can help deliver drugs through hair follicles but struggle to penetrate deeper skin layers.
research A Lipid–Polymer Hybrid Nanoparticle-Loaded Dissolving Microneedle Patch for Promoting Hair Regrowth by Transdermal miR-218 Delivery
The microneedle patch effectively promotes hair regrowth by delivering miR-218.
research Hair Lipid Structure: Effect of Surfactants
Surfactants in shampoos and conditioners remove some but not all lipids from hair, and more research is needed to understand their full impact.
research Development of Tea Seed Oil Nanostructured Lipid Carriers and In Vitro Studies on Their Applications in Inducing Human Hair Growth
Tea seed oil in nanostructured carriers stimulates hair growth and feels less greasy when applied.
research Characterization of Hair Lipid and Protein Dynamics Using EPR Spectroscopy and Treatment Effects
Hair treatments and dehydration affect hair's lipid and protein behavior, influencing its flexibility and appearance.