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Women with PCOS often have more belly fat and higher insulin levels, but belly fat isn't the only cause of their insulin resistance.

Wnt1/βcatenin signaling is crucial for heart repair after injury.

Eph receptors and ephrins may be promising targets for treating diseases, but more understanding is needed for effective and safe therapies.

Biomaterials with MSC-derived substances could improve tissue repair and have advantages over direct cell therapy.

Hair follicles help absorb and store topical compounds, aiding targeted drug delivery.

Visible light can damage skin and most sunscreens don't block it well; more research is needed on its effects and protection methods.

Targeted cancer therapies often cause serious skin problems that need careful management.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

Epigenetic changes control how adult stem cells work and can lead to diseases like cancer if they go wrong.

COVID-19 can cause different skin symptoms that may help with early diagnosis and show how severe the disease is.

Erectile dysfunction is increasingly common in men under 40, with many physical and psychological causes, and various treatment options available.

Low-Level Laser Therapy is effective and safe for hair growth with minimal side effects.

The document concludes that recognizing and treating cutaneous lupus erythematosus early is crucial for managing the skin and potential systemic symptoms.

Silver can help prevent and treat infections but its effectiveness varies and should be weighed against costs and side effects.

Palliative chemotherapy is cost-effective for advanced gastric and colorectal cancer but not clearly for pancreatic-biliary cancer.

Researchers developed promising agents for prostate cancer imaging, with the best one showing high potential for clinical use.

The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.

The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.

Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.

Exosomes could potentially enhance tissue repair and regeneration with lower rejection risk and easier production than live cell therapies.

Antibiotics can reduce acne but may lead to resistant bacteria, and understanding the skin's bacteria is important for treatment.

Substances from Chinese medicines show promise for immune support and disease prevention, but the way they are processed affects their effectiveness.

Men, especially older ones with health issues like prostate cancer, may have worse COVID-19 outcomes and could benefit from therapies targeting male hormones.

Lignans and neolignans from plants may help protect against various health issues, including cancer and heart disease.

FGF signaling is a promising target for developing treatments for wounds, metabolic diseases, and cancer.

The document concludes that better biomarkers are needed to detect long-term oral testosterone use in athletes.

One minoxidil-sensitive potassium channel exists in human hair follicles.

Minoxidil with propranolol and diuretics lowers blood pressure but causes fluid retention and hair growth.

The Wnt/β-catenin pathway helps tissue regeneration but can also cause fibrosis, and drugs that inhibit this pathway may aid in healing skin and heart tissues.

Improving skin barrier and using antifungal treatments can help manage dandruff.