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Treatments that reduce oxidative stress and fix mitochondrial problems may help heal chronic wounds.

Neurosteroids can influence behavior by modulating brain inhibition, with potential for treating psychiatric disorders.

Many substances, including chemicals and metals, can cause skin reactions; careful handling and identification of allergens are crucial to prevent dermatitis.

Reducing Tyrosinase prevents mature color pigment cells from forming in mouse hair.

Treatments for melanin disorders exist, but more effective options needed.

The tumor suppressor gene FLCN affects mitochondrial function and energy use in cells.

The study identified and characterized new keratin genes linked to hair follicles and epithelial tissues.

Targeting glucocorticoid action might help treat type-2 diabetes, but human trials are needed.

The document concludes that Catalyst software is effective for drug design, identifying potent compounds for various medical conditions.

Human skin acts like a hormone-producing organ, making and managing various hormones important for skin and hair health.

Androgen receptors are key for development and health, affecting conditions like prostate cancer and male pattern baldness.

The JAK/STAT pathway is important in cell processes and disease, and JAK inhibitors are promising for treating related conditions.

Intermediate filaments are crucial for cell differentiation and stem cell function.

Diagnosing hyperandrogenism in women is complex and requires accurate testing methods and consideration of SHBG levels.

KATP channels are important for energy balance and are targeted by drugs for diabetes, hypoglycemia, hypertension, and hair loss.

Tissue-derived extracellular vesicles are crucial for cancer diagnosis, prognosis, and treatment.

PF-05314882 selectively activates androgen receptors without much effect on prostate and may help in prostate cancer treatment and hair loss prevention.

The conclusion suggests that prostate cancer should be classified by castration status and that new therapies targeting androgen receptor signaling show promise.

Scientists found out the structure of a human enzyme linked to prostate cancer and hair loss, which could help in designing drugs.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

People with advanced chronic kidney disease often have skin problems, which can be treated with various medications and procedures to improve their quality of life.

Chronic kidney disease can cause skin problems that affect patient quality of life, and treating these conditions can improve outcomes.

The document says biodegradable cosmetics and packaging are better for the environment and user experience.

Olive and olive oil help prevent and manage heart diseases.

Scientists made a carbon-14 labeled version of a drug with a 48% yield and over 99% purity.

Stopping methotrexate might reverse lymphoma-like conditions in some patients.

Some traditional Chinese medicines may have anti-aging benefits and could help with hair growth, but more research is needed.

Mutations at Val-889 and Arg-752 disrupt key interactions in the androgen receptor, affecting its function.

Mutations in the glucocorticoid receptor gene cause reduced sensitivity to glucocorticoids and may lead to poor response to treatment.

The balance between androgen receptor and p53 is crucial for sebaceous gland differentiation.