68 citations
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May 2024 in “International Journal of Molecular Sciences” This review of acne management strategies highlights current treatments, such as topical and systemic therapies, procedural methods, and dietary changes, while also discussing emerging options like biologics and probiotics as potential future treatments, emphasizing personalized care due to acne's complex nature.
36 citations
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January 2023 in “Skin Appendage Disorders” This review discusses the etiology, pathophysiology, trichoscopic characteristics, differential diagnoses, and treatment options for scalp seborrheic dermatitis, without providing new clinical findings.
April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that electrical epilation in organ-cultured human scalp skin perturbs hair follicles by causing inflammation, impairing melanin production, and possibly inhibiting post-epilation hair re-growth.
April 2018 in “Journal of Investigative Dermatology” This article proposes a new classification system for cutaneous adnexal cysts based on their origin in the folliculo-sebaceous unit and sweat glands, aiming to clarify their categorization and origins.
April 2018 in “Journal of Investigative Dermatology” This study identified the osteopontin-derived peptide, FOL-005, as a potential inhibitor of unwanted human hair growth by promoting catagen development without reducing stem cell numbers or showing toxicity.
April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology” The authors concluded that Lrig1-positive stem cells are essential for sebaceous gland formation in mice, as their ablation led to temporary sebaceous gland disappearance without affecting hair growth.
30 citations
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March 2012 in “Journal of Analytical Toxicology” This study found that concentrations of THCCOOH in hair do not correlate well with self-reported cannabis use due to inaccuracies in the self-reported data, but it provides preliminary insights into usage patterns.
120 citations
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April 2009 in “Food Chemistry” This review examines the pharmacological evidence and bioactive compounds in Hibiscus plants, supporting their potential importance for developing treatments for chronic and degenerative diseases, though more research is needed.
This paper discusses advancements in forensic hair analysis, emphasizing a novel DART–HRMS method that improves the accuracy and efficiency of detecting drug use timelines.
69 citations
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December 2005 in “Nature Clinical Practice Endocrinology & Metabolism” Blocking the enzyme 11β-HSD1 might help treat obesity and metabolic issues.
67 citations
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December 2019 in “PloS one” This study found that beta-caryophyllene enhanced re-epithelialization in cutaneous wounds of female mice, suggesting its potential for improving wound healing through multiple pathways.
28 citations
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March 2017 in “Scientific Reports” This study found that minoxidil may protect against chemotherapy-induced peripheral neuropathy and potentially support hair recovery and tumor suppression in mouse models.
22 citations
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November 2011 in “Journal of Analytical Toxicology” This review discusses the relevance of human androgen receptor action in sports doping and examines the potential of cell-based biological assays for detecting androgenic anabolic steroid use, without presenting new research findings.
3 citations
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April 2019 in “bioRxiv (Cold Spring Harbor Laboratory)” In this study, beta-caryophyllene enhanced wound healing in female mice by improving re-epithelialization, cell proliferation, and cell migration, suggesting potential benefits of essential oil compounds in inflammation reduction.
2 citations
,
June 2022 in “Journal of Applied Pharmaceutical Science” This review discusses the pharmacological properties of 4-0-methylhonokiol from Magnolia species and reports no new experimental results, highlighting potential areas for future research.
In this study, a Monte Carlo-generated synthetic cohort analysis found that higher simulated cannabis exposure was linked to increased self-assessed hair loss severity and reduced follicular density, suggesting potential connections worth exploring in further clinical research.
December 2024 in “Deleted Journal” This review explores the challenges of treating chronic wounds and highlights regenerative medicine as a promising approach, emphasizing the roles of growth factors, stem cell therapies, and novel regenerative treatments in improving wound healing and tissue regeneration.
January 2023 in “Advances in pharmacology and clinical trials” This review highlights that human hair is a valuable biological matrix for clinical and toxicological analyses, demonstrating its applicability in detecting various active substances from different pharmacological classes.
134 citations
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April 2020 in “Journal of Cosmetic Dermatology” Male pattern hair loss could hint at androgens affecting COVID-19 severity.
123 citations
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December 2015 in “Journal of Neuroendocrinology” This review discusses recent strategies targeting the neuroactive steroid biosynthetic pathway to enhance neurosteroidogenesis, highlighting their potential benefits for neurodegenerative and neuropsychiatric diseases, but reports no new clinical findings.
48 citations
,
January 2018 in “Scientific Reports” This pilot study found that hair metabolome analysis may help differentiate pregnancy complications from healthy pregnancies by revealing significant metabolite differences between trimesters.
21 citations
,
November 2022 in “Frontiers in immunology” This article reviews sebaceous immunobiology and highlights the complex role of sebaceous glands and sebocytes in skin barrier function and inflammation, particularly in acne pathogenesis, but reports no new results.
1 citations
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January 2023 in “International journal of all research education and scientific methods” This review highlights how forensic drug analysis in hair using modern instrumental techniques offers advantages such as easy sample collection and chronological tracking of drug use, emphasizing its value for law enforcement and other applications.
286 citations
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April 2009 in “The journal of neuroscience/The Journal of neuroscience” This study found that TRPA1-deficient mice exhibited normal cold sensitivity but had decreased mechanical response in nociceptors, suggesting TRPA1's role in mechanotransduction.
130 citations
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August 2015 in “Experimental Dermatology” This review provides a comprehensive guide to serum-free human hair follicle organ culture methods, highlighting research opportunities, standardization efforts, and potential applications without reporting new empirical findings.
127 citations
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June 2008 in “British Journal of Clinical Pharmacology” This study supports the conclusion that the hormetic dose-response model is the most prevalent and fundamental model in biological and biomedical sciences, applicable to a wide range of clinical conditions.
124 citations
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December 2016 in “Pharmaceuticals” This review discusses the functions and potential therapeutic targeting of TRP ion channels in the skin, noting their involvement in both physiological processes and various pathological conditions, but reports no new experimental results.
112 citations
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May 2019 in “Pharmacological Research” This review discusses the isolation, structure, and bioactivity of lignans and neolignans from 2016 to mid-2018, reporting no new clinical results but highlighting their potential protective properties against diseases such as cancer and neurodegeneration.
105 citations
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May 2011 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that activation of the TRPV3 ion channel inhibits human hair growth by affecting hair follicles and outer root sheath keratinocytes.
98 citations
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July 2014 in “Trends in Molecular Medicine” This article discusses the role of human hair follicles in neuroendocrinology and suggests potential new therapeutic targets by examining how neuromediators influence hair growth, pigmentation, and stem cell biology in organ cultures.