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Certain changes to the B-ring of androgen receptor ligands can increase their effectiveness for potential treatments of muscle and bone conditions.

Finasteride modifies 5-alpha-reductases through a two-step process, affecting inhibitor potency and possibly causing side effects.

Pregnancy can cause various skin changes and diseases, with PUPPP being the most common skin condition specific to pregnancy.

Probiotic bacteria improved skin and hair health in aged mice.

Cyproterone acetate is the preferred treatment for women's hyperandrogenism when estrogen/progestogen use is safe.

Researchers made two new compounds that could be used for medicine.

Women with PCOS have a higher risk of diabetes, heart problems, certain cancers, and mental health issues, but early treatment can help manage these risks.

Hair loss in women can be slowed with treatment, but more research needed for better solutions.

Dutasteride works better than finasteride for preventing and treating prostate cancer.

Healthcare claims databases can help monitor drug safety, but may report adverse events differently than direct surveillance.

Most HIV patients develop skin symptoms that can indicate the stage of their disease.

Human hair follicles contain a complex network of prostanoid receptors that may influence hair growth.

Understanding keratinization is crucial for treating skin conditions like ichthyoses and psoriasis.

Classical PCOS types A and B are most common and linked to higher health risks.

TS-SCLF from fermented Schisandra chinensis may promote hair growth and improve hair quality.

Defective mitochondrial DNA replication causes aging symptoms and increased oxidative damage in mice.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

Sex hormones affect reproduction, sexual development, and oral health, and it's important for dental practitioners to understand their effects and interactions.

The document concludes that sex hormones and related compounds have various effects on health, with both potential benefits and risks.

Parkinson's disease is linked to skin disorders and skin cells help in studying the disease.

Cronkhite-Canada syndrome is rare, has a poor prognosis, and requires early diagnosis and ongoing treatment.

The article concludes that better understanding gene regulation related to seasonal changes can offer insights into the mechanisms of seasonal timing in mammals.

The document summarizes medical findings on topics like heart rhythm treatment, sleep apnea therapy, and various health conditions and treatments.

Scientists made a carbon-14 labeled version of a drug with a 48% yield and over 99% purity.

Modern science supports the use of some Ayurvedic plants for health, as ancient practices suggested.

Epirubicin is as effective as doxorubicin for cancer treatment with less heart damage, but doesn't work on doxorubicin-resistant cancers.

Fluconazole is an effective antifungal medication with potential side effects and lacks official analytical methods for its determination.

Minoxidil helps prevent hair loss from chemotherapy in rats.

KY19382 helps regrow hair and create new hair follicles.