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Compartmentalized organization might be crucial for stem cells to effectively respond to growth or injury.

Hedgehog signaling helps keep hair follicle stem cells the same in both young and old human skin.

Male hair loss is caused by inactive hair follicle stem cells.

Removing the ATR gene in adult mice causes rapid aging and stem cell loss.

The document concludes that adult mammalian skin contains multiple stem cell populations with specific markers, important for understanding skin regeneration and related conditions.

Cannabinoid receptor-1 signaling is essential for the survival and growth of human hair follicle stem cells.

HPV16 oncogenes disrupt the normal activity of hair follicle stem cells.

Vav2 and Vav3 proteins help control skin stem cell numbers and activity in both healthy and cancerous cells.

Epidermal stem cells are diverse and vary in activity, playing key roles in skin maintenance and repair.

Stem cells help heal skin wounds by moving and changing roles, working with other cells, and needing more research on their activation and behavior.

Ca_v1.2 affects hair growth and could be a target for hair loss treatments.

Stem cell niches are crucial for regulating stem cell renewal and differentiation, and understanding them can help in developing regenerative therapies.

The conclusion is that the dermal papilla is crucial for hair follicle regrowth, and hair follicles undergo significant structural changes in addition to cell division during regeneration.

Skin and hair renewal is maintained by both fast and slow cycling stem cells, with hair regrowth primarily driven by specific stem cells in the hair follicle bulge. These cells can also help heal wounds and potentially treat hair loss.

Skin aging is due to impaired stem cell mobilization or fewer responsive stem cells.

GDNF helps grow hair and heal skin wounds by acting on hair stem cells.

Disrupting Smad4 in mouse skin causes early hair follicle stem cell activity that leads to their eventual depletion.

Different types of stem cells in the skin contribute to the variety of melanoma forms.

Scientists used a special imaging technique to observe that hair follicle regeneration involves cell division and structural changes, mostly in the lower part of the follicle, and that the dermal papilla at the base is crucial for regrowth.

Lower proximal cup cells, not bulge stem cells, regenerate hair follicles after chemotherapy.

Increased ODC activity leads to skin tumors by recruiting stem cells, not by toxic byproducts.

The marker 5-hmC changes in hair follicle stem cells when they start to grow.

Keratin 15 is not a reliable sole marker for identifying epidermal stem cells because it's found in various cell types.

Basal cell carcinoma mostly starts from cells in the upper skin layers, not hair follicle stem cells.

Removing Lrig1-positive stem cells in mice causes temporary loss of sebaceous glands.

Skin stem cells are crucial for maintaining and repairing the skin and hair, using a complex mix of signals to do so.

Hair grows when stem cell offspring in the follicle base proliferate, influenced by the dermal papilla.

Quercetin significantly helps hair growth by activating hair follicles and improving blood vessel formation around them.

Nerve signals are crucial for hair follicle stem cells to become skin stem cells and help in wound healing.

Damaged hair follicle stem cells can cause permanent hair loss, but understanding their role could lead to new treatments.