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PKC ε increases hair follicle stem cell turnover and may raise skin cancer risk.

Most hair follicle stem cells do not protect their DNA by dividing it unevenly.

The document concludes that adult mammalian skin contains multiple stem cell populations with specific markers, important for understanding skin regeneration and related conditions.

Disrupting Smad4 in mouse skin causes early hair follicle stem cell activity that leads to their eventual depletion.

Lgr5 is a marker for active, long-lasting stem cells in mouse hair follicles.

Vitamin D Receptor is needed for hair growth in mice but not for skin stem cell maintenance.

Bird foot scales develop differently and can repair but not fully regenerate due to the lack of specialized stem cell areas.

Certain transcription factors are key in controlling skin stem cell behavior and could impact future treatments for skin repair and hair loss.

KLF4 is important for maintaining skin stem cells and helps heal wounds.

Disrupted cholesterol production impairs hair follicle stem cells, leading to hair loss.

Stem cell niches are crucial for regulating stem cell renewal and differentiation, and understanding them can help in developing regenerative therapies.

Different types of stem cells with unique roles exist in blood, skin, and intestines, and this variety is important for tissue repair.

Hair can regrow after certain stem cells are lost because other stem cells can take over their role.

Epidermal stem cells have potential for personalized regenerative medicine but need careful handling to avoid cancer.

Skin can heal wounds without hair follicle stem cells, but it takes a bit longer.

A small group of slow-growing cells causes basal cell carcinoma to return after treatment.

Clim proteins are essential for maintaining healthy corneas and hair follicles.

Overexpression of sPLA2-IIA in mouse skin reduces hair stem cells and increases cell differentiation through JNK/c-Jun pathway activation.

Regulating keratinocyte growth in engineered skin can improve wound healing.

Mice lacking a key DNA methylation enzyme in skin cells have a lower chance of activating stem cells necessary for hair growth, leading to progressive hair loss.

Certain human skin cells marked by CD44 and ALDH are rich in stem cells capable of long-term skin renewal.

Aging reduces skin stem cell function, leading to changes like hair loss and slower wound healing.

The hair follicle bulge is an important area for adult stem cells involved in hair growth and repair, with potential for medical use needing more research.

New methods have greatly improved our understanding of stem cell behavior and roles in the body.

Some stem cells in the body rarely divide, which could help create better treatments for diseases and aging.

Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.

Stem cell niches are crucial for regulating stem cell behavior and tissue health, and their decline can impact aging and cancer.

Lgr5 is a marker for active, self-renewing stem cells in the intestine and skin, important for tissue maintenance.

Certain proteins, Lgr5 and Lgr6, are important markers of adult stem cells and are involved in tissue repair and cancer development.

Stem cell offspring help control their parent stem cells, affecting tissue health, healing, and cancer.