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Gene mutations can cause problems in male genital development.

Dutasteride effectively treats benign prostatic obstruction, improves urinary flow, reduces prostate size, and may prevent prostate cancer, but can cause sexual side effects.

Finasteride treats enlarged prostate and baldness, but may cause limited urinary improvement and sex-related side effects.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

New research is needed to create better drugs that block the enzyme responsible for conditions like male baldness and prostate enlargement.

Anti-androgens are effective for female acne but less so for male-pattern hair loss, with side effects similar to birth control pills.

RU 58841 may treat acne, hair loss, and excessive hair growth.

The new particle system could be a promising treatment for diseases related to the 5-α reductase enzyme.

Idiopathic hirsutism causes excessive hair growth in women, can be treated with medication and hair removal, but cannot be fully reversed.

PF-05314882 selectively activates androgen receptors without much effect on prostate and may help in prostate cancer treatment and hair loss prevention.

Lower adrenal hormone levels may cause hair loss in postmenopausal women, certain patterns help diagnose nail cancer, and a gene variant linked to higher skin cancer risk in kidney transplant patients suggests monitoring folate levels.

5α-reductase inhibitors help treat disorders caused by DHT and have potential for future therapies.

Steroid sex hormones activate matriptase in prostate cancer cells but not in breast cancer cells.

Low androgen levels might delay prostate cancer but could lead to more aggressive, therapy-resistant cancers.

Quercetin may help improve symptoms of polycystic ovary syndrome.

Researchers found four natural compounds that can change DHT levels in prostate cancer cells.

5-alpha reductase inhibitors, like finasteride and dutasteride, are used for prostate issues, hair loss, and excessive hair growth, may help with COVID-19, but can cause sexual and mental health side effects, and their use in preventing prostate cancer needs more examination.

Human skin acts like a hormone-producing organ, making and managing various hormones important for skin and hair health.

Sex steroids produced in the hippocampus are crucial for brain functions like memory and learning in rodents.

Athletes use steroids to enhance performance despite health risks and legal issues, and education on their dangers is needed.

Men are more likely to get infectious skin diseases, while women are more prone to autoimmune and pigment-related skin conditions, influenced by biological and environmental factors.

Muscles can make their own androgens, which may help muscle growth.

Finasteride shows promise for treating hair loss and excessive hair growth, but more research is needed to confirm its effectiveness and safety.

Baicalin may help reduce excessive male hormone levels in PCOS.

DHT affects bone growth by altering gene activity in osteoblasts, potentially complicating steroid use.

Guava leaf extract may help treat hair loss and protect cells by blocking certain genes and fighting damaging molecules.

Cinnamon may help manage obesity and improve conditions related to Polycystic Ovary Syndrome (PCOS).

Hormones like androgens, estrogen, thyroid hormones, and stress hormones can contribute to hair loss, and treatments target these hormonal imbalances.

Some medications might contribute to male infertility, with finasteride showing a high number of reports.

New liposome treatment successfully delivers CRISPR to deactivate a key enzyme in androgen-related disorders.