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Methotrexate is a key, cost-effective drug for skin conditions, but requires careful monitoring for side effects.

The conclusion is that hair growth can be improved by activating hair cycles, changing the surrounding environment, healing wounds to create new hair follicles, and using stem cell technology.

Long-term testosterone therapy can cause hormone suppression, affect prostate and heart health, and alter physical characteristics, but does not increase prostate cancer risk and needs more research for full risk assessment.

Electrospun nanofibers show promise for enhancing blood vessel growth in tissue engineering but need further research to improve their effectiveness.

Hair follicle stem cells are controlled by their surrounding environment.

Wnt1a-conditioned medium from stem cells helps activate cells important for hair growth and can promote hair regrowth.

Certain signals and genes play a key role in hair growth and regeneration, and understanding these could lead to new treatments for skin regeneration.

Male pattern baldness is mostly inherited, involves many genes, and is linked to other traits like early puberty and strong bones.

Ablative fractional resurfacing could improve how well topical drugs penetrate the skin, but more research is needed to fine-tune the method.

Research on epidermal stem cells has advanced significantly, showing promise for improved clinical therapies.

Bariatric surgery can worsen nutritional deficiencies, requiring careful monitoring and supplementation.

Wnt10b helps blood stem cells grow after injury.

Noggin gene inactivation causes skeletal defects in mice, varying by genetic background.

Activin B improves wound healing and hair growth by helping stem cells move using certain cell signals.

Many patients find hair loss from chemotherapy very distressing, and while treatments like minoxidil and scalp cooling may help, there is no sure way to prevent it.

Damaging mitochondrial DNA in mice speeds up aging due to increased reactive oxygen species, not through the p53/p21 pathway.

RADA16 is a promising material for tissue repair and regenerative medicine but needs improvement in strength and cost.

Stem cell therapy may help treat tough hair loss cases.

Selective androgen receptor modulators (SARMs) are a promising type of drug for various health conditions due to their targeted actions.

Androgen is important in controlling stem cell differentiation, reducing fat development, and increasing lean mass.

Genetically-altered adult stem cells can help in wound healing and are becoming crucial in regenerative medicine and drug design.

The document concludes that inherited epidermolysis bullosa is a challenging genetic condition requiring multidisciplinary care and new treatments.

BMP2 needs periosteal tissue to help regenerate mouse middle finger bones within a specific time.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

Stem cells could improve plastic surgery but are not widely used due to cost and safety concerns.

Isoproterenol helps hair follicle stem cells turn into beating heart muscle cells.

HVDRR is caused by VDR gene mutations, leading to vitamin D resistance, treatable with high calcium doses, but alopecia remains permanent.

Tiny vesicles from stem cells could be a new treatment for healing wounds.

3D-printed mesoporous scaffolds show promise for personalized drug delivery with controlled release.

CXXC5 is a protein that controls cell growth and healing processes, and changes in its activity can lead to diseases like cancer and hair loss.