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Ishige sinicola extract helps bone-building cells grow and mature, which could aid in treating osteoporosis.

Mitochondrial Complex I reduces inflammation and increases bone breakdown by affecting certain immune cells.

RANK is a key target in breast cancer treatment due to its role in tumor growth and bone metastasis.

Dutasteride and finasteride do not significantly affect bone density, blood fats, or blood production, but slightly lower PSA levels and minimally impact sexual function in healthy young men.

Managing side effects of endocrine therapy is crucial to improve adherence and survival in breast cancer patients.

Glucocorticoids can cause various health issues, but some treatments may help reduce these effects.

Cepharanthine has many medicinal uses but needs improvement for better effectiveness.

Testosterone therapy increases bone density in older men with low testosterone levels.

People with hidradenitis suppurativa often have lower vitamin D levels, weaker hip bones, and altered bone metabolism markers.

Some natural compounds from Iris plants can block enzymes related to certain disorders, with a few affecting both targeted enzymes.

Long-term finasteride use doesn't change bone density or metabolism.

Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.

The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

The document discusses hair and nail conditions, updates on treatments for alopecia, and controversies around finasteride use.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

Cooling the scalp may prevent hair loss from chemotherapy, hair often grows back after treatment, and nail issues usually improve after stopping the drug.

Rapamycin treatment helps with mitochondrial disease by reducing PKC levels.

Rapamycin may help treat Leigh syndrome by targeting protein kinase C.

NF-κB signaling is crucial in many diseases and can be targeted for new treatments.

Vitamin D is important for bones, hair, blood pressure, and breast development.

Coumarin derivatives show promise as anti-estrogenic agents for treating breast cancer, with some in clinical trials.

Vitamin D receptor interacts with certain dietary components to help prevent diseases and regulate hair growth.

Costunolide may have multiple health benefits, including promoting hair growth and protecting against cancer and diabetes, but more research is needed.

The paper suggests that hair loss might be caused by skull growth, not just DHT's effect on hair follicles, and calls for more research.

The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

Some heart drugs show promise for other conditions, but more research is needed to confirm their effectiveness and safety.

Selective Androgen Receptor Modulators (SARMs) are drugs that can control the effects of androgens in different tissues, potentially having fewer side effects and promising for treating various conditions.

Testosterone is crucial for development, growth, and various body functions in mammals.