Free Papers Medical and Surgical: Hair and Nails

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    Alopecia Areata →

    autoimmune disorder causing patchy hair loss

    Finasteride →

    Frontline, gold standard treatment for combatting androgenic alopecia

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    Studysummary This article discusses factors contributing to aseptic loosening of implants and explores the challenges of determining metal hypersensitivity testing in patients, but provides no new clinical results.
    Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer
    The document provides summaries of presentations from a dermatology conference, focusing on various conditions related to hair and nails, as well as treatment updates for alopecia areata and frontal fibrosing alopecia. Onychopapilloma, a benign neoplasm of the nailbed and matrix, is discussed with its typical presentation and treatment options. Late onset malalignment of the nails is also covered, highlighting its clinical signs and management. For alopecia areata, the consensus statement outlines a treatment algorithm, including indications for systemic treatment and potential systemic treatments like glucocorticosteroids, methotrexate, and JAK inhibitors. The efficacy and safety of JAK inhibitors for alopecia areata are also presented, with phase 2a trial data for two novel inhibitors. Frontal fibrosing alopecia's pathogenesis and treatment are updated, noting the difficulty in treatment and the lack of randomized controlled trials with objective endpoints. Controversies surrounding finasteride treatment for androgenetic alopecia are discussed, including its impact on family planning, cancer risks, and post-finasteride syndrome. The document does not provide specific numbers of people involved in the studies or trials mentioned.
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