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Methotrexate treats various disorders by inhibiting DNA synthesis, but careful monitoring is needed to avoid toxicity and manage side effects.

Male and female skin differ due to hormones, affecting conditions like hair loss, acne, and skin cancer, and suggesting a need for gender-specific treatments.

Stem cell self-renewal is complex and needs more research for full understanding.

Researchers developed promising agents for prostate cancer imaging, with the best one showing high potential for clinical use.

The document concludes that accurate diagnosis of ichthyosis is crucial for treatment and genetic advice, and ongoing research is needed for better therapies.

Cancer cells often have more copies of TERT and TERC genes, which helps them grow and could affect patient outcomes.

Protoporphyrin IX is useful in cancer treatment but can cause health problems if not properly regulated.

PRP treatment improves hair growth, and the device used can affect results, with some being more effective.

The drug IPI-926 is safe at 160 mg daily and may help treat certain tumors, especially basal cell carcinoma.

Some vitamins and minerals like vitamin D and iron can help with certain types of hair loss, but more research is needed for others.

The document concludes that specific cells are essential for hair growth and more research is needed to understand how to maintain their hair-inducing properties.

Mouse hair follicle cells briefly grow during the early hair growth phase, showing that these cells are important for starting the hair cycle.

Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.

Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.

Hair follicles produce and respond to melatonin, affecting hair growth and sensitivity to estrogen.

Hibiscus plant extracts may have health benefits like lowering blood pressure and protecting the heart.

Modern lifestyles, including poor diet, stress, and long-term use of certain medications, hinder the body's ability to heal from inflammation, leading to chronic diseases.

Hair grows faster in the morning and is more vulnerable to damage from radiation due to the internal clock in hair follicle cells.

Scientists turned rat thymus cells into stem cells that can help repair skin and hair.

Wnt and Notch signaling help wound healing by promoting cell growth and regulating cell differentiation.

Skin's Regulatory T cells are crucial for maintaining skin health and could be targeted to treat immune-related skin diseases and cancer.

Minoxidil is the only FDA-approved topical drug for treating male or female pattern hair loss, and other medications like finasteride and dutasteride can also increase hair growth.

Melatonin helps regulate hair growth and protects the hair follicle from stress.

Formyl-peptide receptor agonists could be new anti-inflammatory drugs.

Recombinant cytokine therapy can cause skin reactions ranging from mild to severe.

Chemotherapy often causes temporary hair loss, which is distressing and needs better treatment and support.

A mother's PPARγ is crucial for preventing harmful milk that can cause inflammation and growth problems in babies.

5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.

The document concludes that certain genetic mutations and dietary factors are involved in acne development, and treatments like isotretinoin and diet changes can help manage it.

Oxidative stress affects hair loss in men with androgenetic alopecia.